Nucleotides and Nucleic Acids Quiz

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Questions and Answers

Match the following components with their respective nucleic acids:

Deoxyribose = DNA Ribose = RNA Thymine = DNA Uracil = RNA

Match the following processes with their descriptions:

DNA replication = Semi-conservative replication ensuring genetic continuity Hydrolysis of ATP = Release of energy to form ADP Condensation of ADP = Production of ATP during respiration Phosphorylation = Making compounds more reactive

Match the following nitrogenous bases with their corresponding nucleic acids:

Adenine = Both DNA and RNA Cytosine = Both DNA and RNA Guanine = Both DNA and RNA Thymine = DNA only

Match the following terms with their definitions:

<p>Polynucleotide = A long chain of nucleotides Phosphodiester bond = Link between nucleotide monomers Condensation reaction = Process that forms bonds by releasing water Hydrogen bond = Non-covalent interaction between bases</p> Signup and view all the answers

Match the following roles to nucleic acids:

<p>DNA = Holds genetic information RNA = Transfers genetic information ATP = Energy carrier ADP = Formed from ATP hydrolysis</p> Signup and view all the answers

Match the following enzymes with their functions:

<p>ATP hydrolase = Catalyses the hydrolysis of ATP ATP synthase = Catalyses condensation of ADP DNA polymerase = Synthesizes new DNA strands Ligase = Joins DNA fragments together</p> Signup and view all the answers

Match the following features to DNA or RNA:

<p>Double helix = DNA Single polynucleotide chain = RNA Contains thymine = DNA Contains uracil = RNA</p> Signup and view all the answers

Match the following types of sugars with their corresponding nucleotides:

<p>Ribose = RNA nucleotide Deoxyribose = DNA nucleotide Glucose = Not a nucleotide component Mannose = Not a nucleotide component</p> Signup and view all the answers

Match the following genetic conditions with their descriptions:

<p>Cystic fibrosis = Caused by a mutation leading to sticky mucus Sickle cell anaemia = Mutation causing distorted red blood cells Hemophilia = A genetic disorder affecting blood clotting Duchenne muscular dystrophy = A condition causing muscle degeneration</p> Signup and view all the answers

Match the stages of protein synthesis with their respective definitions:

<p>Transcription = Process of synthesizing mRNA from DNA Translation = Assembly of amino acids into a polypeptide chain Replication = Copying of DNA to produce identical strands Post-translational modification = Changes made to proteins after synthesis</p> Signup and view all the answers

Match the components of transcription with their roles:

<p>RNA polymerase = Enzyme that synthesizes mRNA DNA template = Strand used to create mRNA Free nucleotides = Building blocks of the mRNA strand mRNA = Final product of transcription</p> Signup and view all the answers

Match the following processes with their descriptions during DNA replication:

<p>Unwinding = Separation of DNA strands by breaking hydrogen bonds Base pairing = Joining of free nucleotides to template strands Phosphodiester bond formation = Joining of adjacent nucleotides through condensation reactions Template strands = Strands used to guide the formation of new DNA strands</p> Signup and view all the answers

Match the following types of RNA with their functions:

<p>mRNA = Transports code from DNA to ribosomes tRNA = Transfers specific amino acids during translation rRNA = Constitutes the structure of ribosomes snRNA = Involved in RNA splicing</p> Signup and view all the answers

Match the following features of the genetic code:

<p>Non-overlapping = Each triplet is read only once Degenerate = Multiple triplets can code for the same amino acid Phenotypic effect of mutations = Reduced by the degeneracy of the genetic code Codon = Specific sequence that designates an amino acid</p> Signup and view all the answers

Match the following terms with their roles in protein synthesis:

<p>Peptide bonds = Connections between amino acids in a polypeptide chain Genetic code = Sequence of bases coding for amino acids Polypeptide chain = Resulting structure from the joining of amino acids Mutations = Changes in base sequences that can affect proteins</p> Signup and view all the answers

Match the following codons with their roles:

<p>Start codon = Initiates protein synthesis Stop codon = Terminates protein synthesis Codon = Triplet of bases coding for an amino acid Anticodon = Triplet of bases on tRNA complementary to mRNA</p> Signup and view all the answers

Match the following enzymes with their functions in DNA replication:

<p>DNA polymerase = Enzyme that joins adjacent nucleotides DNA helicase = Enzyme that separates DNA strands Ligase = Enzyme that joins broken strands together Primase = Enzyme that synthesizes RNA primers for initiation</p> Signup and view all the answers

Match the types of mutations with their descriptions:

<p>Point mutation = Change in a single nucleotide Insertion = Addition of one or more nucleotides Deletion = Removal of one or more nucleotides Frameshift mutation = Shift in reading frame due to insertion or deletion</p> Signup and view all the answers

Match the following types of mutations with their descriptions:

<p>Base deletion = Removal of a base from the DNA sequence Base insertion = Addition of an extra base into the DNA sequence Base substitution = Replacement of one base with another base Silent mutation = Change that does not affect the amino acid sequence</p> Signup and view all the answers

Match the following statements with the correct concepts in DNA structure:

<p>Hydrogen bonds = Hold the two strands of DNA together Complementary base pairing = A pairs with T and C pairs with G Condensation reactions = Forms phosphodiester bonds between nucleotides Strands of DNA = Run in opposite directions and are antiparallel</p> Signup and view all the answers

Match the following components of the genetic code with their characteristics:

<p>Amino acids = Building blocks of proteins Genes = Sequences of bases coding for polypeptides Codons = Three-base combinations specifying amino acids Ribosomes = Sites of protein synthesis within the cell</p> Signup and view all the answers

Flashcards

DNA

A type of nucleic acid that carries genetic information from one generation to the next.

RNA

A type of nucleic acid involved in protein synthesis. It carries genetic information from DNA to ribosomes.

Nucleotide

A monomer that makes up nucleic acids; consisting of a phosphate group, a pentose sugar, and a nitrogenous base.

Deoxyribose

The sugar found in DNA. It has one less oxygen atom than ribose.

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Ribose

The sugar found in RNA. It is a 5-carbon sugar.

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Adenine (A)

One of the four nitrogenous bases found in DNA. It pairs with thymine.

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DNA Replication

The process by which a DNA molecule is copied into two identical DNA molecules. The original DNA strands separate and act as templates for the synthesis of new complementary strands.

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ATP

A molecule that provides energy for cellular processes. It is a nucleotide derivative consisting of adenine, ribose, and three phosphate groups.

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Semi-conservative replication

The process of creating two identical DNA molecules from one original DNA molecule. The original DNA strands separate and act as templates for the synthesis of new complementary strands.

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DNA helicase

An enzyme that unwinds the double helix of DNA by breaking the hydrogen bonds between the complementary bases.

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DNA polymerase

A type of enzyme that joins adjacent nucleotides together in a DNA strand by forming phosphodiester bonds.

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Codon

The triplet of bases on a DNA molecule that codes for a specific amino acid.

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Introns

The non-coding sections of DNA that are typically removed before protein synthesis.

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Exons

The coding regions of DNA that contain the instructions for making proteins.

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Mutation

A mistake in the base sequence of DNA that can alter the amino acid sequence and the protein.

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Cystic fibrosis mutation

A mutation in a gene that causes the production of sticky mucus, leading to difficulty breathing and other complications.

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Sickle cell anaemia mutation

A mutation in the gene responsible for haemoglobin production, causing red blood cells to become sickle-shaped, leading to reduced oxygen transport.

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Start codon

A three-nucleotide sequence within mRNA that signals the start of protein synthesis.

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Stop codon

A three-nucleotide sequence within mRNA that signals the end of protein synthesis.

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Transcription

The process of copying genetic information from DNA into mRNA.

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Translation

The process of using mRNA to create a polypeptide chain.

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Study Notes

Nucleotides and Nucleic Acids

  • DNA and RNA carry genetic information
  • DNA holds genetic information, RNA transfers this information
  • DNA and RNA are polymers of nucleotides
  • Nucleotides consist of a pentose sugar, a nitrogenous base, and a phosphate group
  • DNA nucleotides: deoxyribose, phosphate, adenine, cytosine, guanine, or thymine
  • RNA nucleotides: ribose, phosphate, adenine, cytosine, guanine, or uracil
  • Nucleotides join together by phosphodiester bonds in condensation reactions
  • DNA is a double helix with two polynucleotides joined by hydrogen bonds between complementary bases
  • RNA is a single polynucleotide chain

ATP

  • Adenosine triphosphate (ATP) is a nucleotide derivative
  • ATP consists of ribose, adenine, and three phosphate groups
  • Energy released when ATP is hydrolysed to ADP and a phosphate molecule
  • This process is catalysed by ATP hydrolase
  • Inorganic phosphate can phosphorylate other compounds, making them more reactive
  • ATP synthase produces ATP during photosynthesis and respiration

DNA Replication

  • Semi-conservative replication ensures genetic continuity between generations
  • Steps of DNA replication:
    • Double helix unwinds (DNA helicase)
    • Hydrogen bonds between complementary bases break, separating strands
    • Each strand acts as a template
    • Complementary base pairing occurs
    • Adjacent nucleotides join by phosphodiester bonds using DNA polymerase
    • Two identical DNA molecules are formed

Genetic Code

  • Genetic code is the order of bases on DNA
  • Each triplet of bases (codon) codes for a particular amino acid
  • Amino acids are joined by peptide bonds to form a polypeptide chain
  • A gene is a sequence of bases coding for a sequence of amino acids in a polypeptide chain
  • Features of genetic code: non-overlapping, degenerate (more than one codon for some amino acids)

Protein Synthesis

  • Two stages: transcription and translation
  • Transcription:
    • DNA is transcribed into mRNA in the nucleus
    • Hydrogen bonds break, DNA strands separate, one strand acts as a template
    • RNA polymerase creates mRNA molecule using complementary base pairing
    • mRNA leaves the nucleus
  • Translation:
    • mRNA attaches to a ribosome
    • tRNA carries amino acids to the ribosome
    • tRNA anticodon pairs with mRNA codon
    • Amino acids join by peptide bonds, forming a polypeptide chain
    • Process continues until a stop codon is reached

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