Nucleophilic Acyl Substitution
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Nucleophilic Acyl Substitution

Learn about the mechanism of nucleophilic acyl substitution, a type of reaction involving the addition of a nucleophile to an acyl compound. Understand the reaction of acid chlorides with alcohols and the concept of ethanoylation.

Created by
@MercifulBoron

Questions and Answers

What is the common feature of all acid derivatives?

The presence of an alkyl or acyl group

What is the purpose of using sulphur dichloride oxide in the preparation of acid chlorides?

To drive off hydrogen chloride and sulphur dioxide as gases

What is the product of the reduction of carboxylic acids using lithium tetrahydridoaluminate(III) in dry ethoxyethane?

The corresponding alcohol

What is the catalyst used in the chlorination of ethanoic acid to form monochloroethanoic acid?

<p>All of the above</p> Signup and view all the answers

What is the reason why carboxylic acids cannot be reduced to the corresponding aldehyde directly?

<p>They are resistant to reduction by many common reducing agents</p> Signup and view all the answers

What is the characteristic of acid chlorides?

<p>They are colourless liquids with Pungent smells</p> Signup and view all the answers

What is the reaction involved in the preparation of acid chlorides?

<p>The reaction of the carboxylic acid and phosphorus(V) chloride or sulphur dichloride oxide</p> Signup and view all the answers

What is the intermediate formed in the reduction of carboxylic acids using lithium tetrahydridoaluminate(III) in dry ethoxyethane?

<p>Alkoxide</p> Signup and view all the answers

Why are nitriles considered as acid derivatives?

<p>Because they can be obtained from carboxylic acids</p> Signup and view all the answers

What is the purpose of using lithium tetrahydridoaluminate(III) in dry ethoxyethane in the reduction of carboxylic acids?

<p>To reduce the carboxylic acid to the corresponding alcohol</p> Signup and view all the answers

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