Nucleic Acids Overview

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Questions and Answers

What are the two types of nucleic acids?

  • RNA and Protein
  • Polynucleotide and Mononucleotide
  • Adenine and Guanine
  • Deoxyribonucleic acid (DNA) and Ribonucleic acid (RNA) (correct)

Which structure is formed when nucleotides bond together?

  • Glycosidic bond
  • Hydrophobic interaction
  • Peptide bond
  • Phosphodiester linkage (correct)

Which nitrogenous bases are found in DNA?

  • Adenine, Uracil, Cytosine, Guanine
  • Guanine, Cytosine, Uracil, Thymine
  • Adenine, Thymine, Uracil, Cysteine
  • Adenine, Thymine, Cytosine, Guanine (correct)

What type of reaction leads to the formation of nucleic acid chains?

<p>Condensation reaction (C)</p> Signup and view all the answers

What type of sugar is found in RNA?

<p>Ribose (D)</p> Signup and view all the answers

How are the two strands of DNA held together?

<p>Hydrogen bonds (C)</p> Signup and view all the answers

Which of the following correctly describes the structure of DNA?

<p>Double helix with deoxyribose sugar (C)</p> Signup and view all the answers

What is the process called when RNA is synthesized from DNA?

<p>Transcription (D)</p> Signup and view all the answers

Flashcards

What are nucleic acids?

Nucleic acids are complex biopolymers that play crucial roles in storing, transmitting, and expressing genetic information within organisms.

What is DNA?

DNA is the blueprint for life, storing genetic instructions that determine an organism's traits. It's a double-stranded helix, with each strand composed of nucleotides.

What is RNA?

RNA plays a crucial role in protein synthesis, relaying genetic instructions from DNA to ribosomes. It's a single-stranded molecule.

What is a nucleotide?

A nucleotide is a building block of nucleic acids. It consists of a sugar molecule, a phosphate group, and a nitrogenous base.

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What are purines?

Adenine (A) and Guanine (G) belong to the purine family, both having two fused rings. They pair with thymine (T) and cytosine (C) respectively.

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What are pyrimidines?

Cytosine (C) and Thymine (T) belong to the pyrimidine family, both having a single ring. Uracil replaces Thymine in RNA.

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How do the two strands of DNA attach?

The two strands of DNA are held together by hydrogen bonds forming between complementary base pairs. A pairs with T, and G pairs with C.

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How does the sugar-phosphate backbone form?

The sugar-phosphate backbone of nucleic acids is formed by phosphodiester linkages. This linkage forms between the phosphate group of one nucleotide and the sugar of the next.

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Study Notes

Nucleic Acids

  • Nucleic acids are informational polymers
  • They store hereditary information
  • They are the only molecules capable of self-replication
  • Two types: DNA and RNA
  • Other functions include storing chemical energy (ATP), acting as enzymes, and as signal molecules

Types of Nucleic Acids

  • Deoxyribonucleic acid (DNA)
  • Ribonucleic acid (RNA)

DNA Structure

  • DNA encodes the information directing cellular activity
  • DNA blueprints RNA synthesis for protein synthesis

Nucleotide Structure

  • Nucleotides are monomers, building blocks of nucleic acids
  • Polynucleotides (DNA and RNA) are polymers
  • Nucleotides form polynucleotides through condensation reactions
  • A nucleotide consists of:
    • Nucleoside (sugar + base)
    • Phosphate group

Pentose Sugar

  • Five-carbon ring sugar
  • Two types: Ribose (RNA) and Deoxyribose (DNA)
  • Phosphate group attaches to the 5' carbon of the sugar

Nitrogenous Bases

  • Two families: Purines and pyrimidines
    • Purines (two rings): Adenine and Guanine
    • Pyrimidines (one ring): Cytosine, Thymine (DNA), and Uracil (RNA)

Phosphodiester Linkage

  • Nucleotides bond through phosphodiester linkages, forming a sugar-phosphate-sugar-phosphate backbone
  • The sugars in the backbone vary depending on the attached nitrogenous base (glycosyl bond)

DNA Structure (Double Helix)

  • DNA is a double helix
  • Strands held together by hydrogen bonds between complementary base pairs
  • Antiparallel structure (strands run in opposite directions)
  • Complementary base pairing (purine + pyrimidine):
    • A – T (2 hydrogen bonds)
    • G – C (3 hydrogen bonds)

RNA Structure (Single Strand)

  • RNA is single-stranded
  • RNA sugar is ribose

DNA vs RNA

Feature DNA RNA
Sugar Deoxyribose Ribose
Bases A, T, C, G A, U, C, G
Structure Double helix Single strand
Function Stores genetic information; directs RNA and protein synthesis Involved in protein synthesis; carries genetic message; etc

Practice Questions Answers

  1. d. Polynucleotide
  2. c. Amine
  3. d. Hydrogen bond

Linkages Table

Biomolecule Linkage
Protein Peptide Bond
Carbohydrate Glycosidic Linkage
Nucleic Acid Phosphodiester Linkage
Lipid Ester Linkage

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