NPR3 Enzyme and ANP Effects Quiz

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6 Questions

What is the function of NPR3?

Implicated in the metabolic clearance of natriuretic peptides

What is the acute effect of ANP infusion in patients with congestive heart failure?

Reduction of systemic vascular resistance

What is the endogenous ligand of NPR3 that is secreted by bone and muscle cells?

Osteocrin

What is the major role of endogenous natriuretic peptides in blood pressure regulation?

Play major roles in blood pressure regulation

In genetically engineered mice, which specific knockout resulted in hypertension?

Endothelial cell-specific GC-A knockout (EC-GC-A-KO)

According to studies, which system is of greater importance in long-term blood pressure regulation?

Endothelial ANP/BNP–GC-A system

Test your knowledge on the NPR3 enzyme, its role in cyclic GMP conversion, and the effects of ANP on vascular resistance. Learn about NPR3 also known as NPR-C and its involvement in natriuretic peptides metabolism.

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