NPNs and Kidney Function Test
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Questions and Answers

What is the major excretory product of protein metabolism?

  • Blood urea nitrogen (correct)
  • Ammonium ion
  • Glutamate
  • Oxoglutarate

Which method is commonly used for the analytical determination of Urea?

  • Glutamate dehydrogenase method (correct)
  • NADH method
  • Oxoglutarate method
  • pH method

What is the role of Non-Protein Nitrogens in assessing the status of the kidney?

  • To excrete waste products
  • To assess kidney function (correct)
  • To promote kidney function
  • To regulate pH balance

What happens to some of the filtered Urea in the renal tubules?

<p>It is reabsorbed by passive diffusion (D)</p> Signup and view all the answers

What determines the concentration of Urea in the blood?

<p>Renal function, perfusion, diet protein content, and rate of protein catabolism (D)</p> Signup and view all the answers

What is the initial step in the coupled enzymatic method for Urea determination?

<p>Conversion of Urea to Ammonium ion by enzyme Urease (C)</p> Signup and view all the answers

What is the main method used for the detection of blood urea nitrogen (BUN)?

<p>Chemical method (Diacetylmonoxime method) (B)</p> Signup and view all the answers

Which specimen can be used for the analysis of blood urea nitrogen (BUN)?

<p>Plasma, Serum, or Urine (B)</p> Signup and view all the answers

What should be avoided in samples for the analysis of blood urea nitrogen (BUN) due to their inhibitory effects on Urease?

<p>Sodium citrate and fluoride (D)</p> Signup and view all the answers

What is the clinical application of the analysis of blood urea nitrogen (BUN)?

<p>To evaluate renal function and verify adequacy of dialysis (D)</p> Signup and view all the answers

What does elevated concentration of NPNs in the body refer to as per the text?

<p>Azotemia (C)</p> Signup and view all the answers

Which type of azotemia is caused by problems of the kidney itself?

<p>Renal azotemia (D)</p> Signup and view all the answers

What is the main source of blood uric acid production?

<p>&quot;Product of Purine Catabolism (Adenosine and Guanine) in the liver&quot; (A)</p> Signup and view all the answers

What does a concentration of >6.8 mg/dl of uric acid in the blood indicate?

<p>&quot;Concentrations of &gt; 6.8 mg/dl, crystals may form in the tissues.&quot; (A)</p> Signup and view all the answers

Which method lacks specificity in the analysis of uric acid?

<p>&quot;Caraway Method&quot; (B)</p> Signup and view all the answers

What can the analysis of blood uric acid be used for?

<p>&quot;To detect kidney dysfunction and diagnosis and treatment of gout&quot; (D)</p> Signup and view all the answers

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