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16 Questions

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NPNs and Kidney Function Test

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Questions and Answers

What is the major excretory product of protein metabolism?

Blood urea nitrogen (correct)

Ammonium ion

Glutamate

Oxoglutarate

Which method is commonly used for the analytical determination of Urea?

Glutamate dehydrogenase method (correct)

NADH method

Oxoglutarate method

pH method

What is the role of Non-Protein Nitrogens in assessing the status of the kidney?

To excrete waste products

To assess kidney function (correct)

To promote kidney function

To regulate pH balance

What happens to some of the filtered Urea in the renal tubules?

It is reabsorbed by passive diffusion Signup and view all the answers

What determines the concentration of Urea in the blood?

Renal function, perfusion, diet protein content, and rate of protein catabolism Signup and view all the answers

What is the initial step in the coupled enzymatic method for Urea determination?

Conversion of Urea to Ammonium ion by enzyme Urease Signup and view all the answers

What is the main method used for the detection of blood urea nitrogen (BUN)?

Chemical method (Diacetylmonoxime method) Signup and view all the answers

Which specimen can be used for the analysis of blood urea nitrogen (BUN)?

Plasma, Serum, or Urine Signup and view all the answers

What should be avoided in samples for the analysis of blood urea nitrogen (BUN) due to their inhibitory effects on Urease?

Sodium citrate and fluoride Signup and view all the answers

What is the clinical application of the analysis of blood urea nitrogen (BUN)?

To evaluate renal function and verify adequacy of dialysis Signup and view all the answers

What does elevated concentration of NPNs in the body refer to as per the text?

Azotemia Signup and view all the answers

Which type of azotemia is caused by problems of the kidney itself?

Renal azotemia Signup and view all the answers

What is the main source of blood uric acid production?

"Product of Purine Catabolism (Adenosine and Guanine) in the liver" Signup and view all the answers

What does a concentration of >6.8 mg/dl of uric acid in the blood indicate?

"Concentrations of > 6.8 mg/dl, crystals may form in the tissues." Signup and view all the answers

Which method lacks specificity in the analysis of uric acid?

"Caraway Method" Signup and view all the answers

What can the analysis of blood uric acid be used for?

"To detect kidney dysfunction and diagnosis and treatment of gout" Signup and view all the answers