Nosocomial Infections: S.aureus

infections that arent present upon hospital admission ut occur in patients during hospital stay. they are associated with medical devices,. surgical wounds, blood stream infections associated with ventilation and surgical site infections

skin and soft tissue infections, bone and joint infections, heart valve infections, medical implant infections and bacteria in the blood

produces a range of surface proteins, enzymes and secreted toxins. has several adhesins that aid in attachment to host cell surfaces and bind to host cell receptors. invasion: when there's a breach in the epithelial skin layer s.aureus is able to penetrate lower levels of tissue if immune response fails to kill the bacteria it can penetrate deeper and enter the bloodstream. biofilm formation: biofilms can form on tissue or surgical devices such as cathters and are not easily penetratable by antibiotics. intracellular survival, multiplication and lysis of host cells.

<p>modification of the drug target, enzymatic inactivation of the drug and active efflux of the drug</p> Signup and view all the answers

<p>methicillin-sensitive strains are treated with penicillin derivatives like oxacillin. methicillin-resistant strains are treated with vancomycin</p> Signup and view all the answers