Questions and Answers
What is an FDA-approved indication for the use of normal saline infusion?
Extracellular fluid replacement
What is normal saline commonly used as in addition to its infusion?
A diluent for the infusion of compatible drug additives
What is a non-FDA-approved indication for the use of normal saline infusion?
Replacement fluid in hyperkalemia
In what condition is normal saline preferred for diluting packed red blood cells prior to transfusion?
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What is a condition in which normal saline is used due to severe hypovolemia and low serum sodium levels?
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Study Notes
Normal Saline (0.9% Sodium Chloride) Indications
- FDA-approved indications for normal saline infusion:
- Extracellular fluid replacement (e.g., dehydration, hypovolemia, hemorrhage, sepsis)
- Treatment of metabolic alkalosis with fluid loss
- Mild sodium depletion
- Additional uses:
- Diluent for compatible drug additives
- Other indications:
- Traumatic brain injury or brain edema
- Replacement fluid in hyperkalemia
- Preferred solution for diluting packed red blood cells prior to transfusion
- DKA treatment with severe hypovolemia and serum sodium < 140meq/L
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