Normal Haemostasis Quiz

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Questions and Answers

What allows rapid formation of solid blood clots to seal rupture or injury to blood vessels?

  • Functions of coagulation system
  • Adequacy and function of platelets (correct)
  • Integrity of the vessel wall
  • Vasoconstriction due to neurogenic mechanisms

What is the primary function of endothelial injury in haemostasis?

  • Activation of coagulation pathway
  • Release of secretory granules
  • Synthesis of tissue factor
  • Exposing thrombogenic subendothelial extracellular matrix (correct)

What is the role of thrombin in secondary haemostasis?

  • Synthesis of tissue factor
  • Conversion of fibrinogen into fibrin (correct)
  • Activation of coagulation pathway
  • Formation of haemostatic plug

What initiates the coagulation pathway in secondary haemostasis?

<p>Synthesis of tissue factor by endothelium (A)</p> Signup and view all the answers

What causes the brief period of vasoconstriction at the site of injury?

<p>Reflux neurogenic mechanisms (B)</p> Signup and view all the answers

What is the primary function of haemostatic mechanisms?

<p>To allow rapid formation of solid blood clots to seal rupture or injury to blood vessels (C)</p> Signup and view all the answers

What is the primary role of the endothelial injury in primary haemostasis?

<p>To expose highly thrombogenic subendothelial extracellular matrix, allowing platelet adhesion and activation (D)</p> Signup and view all the answers

What is the function of thrombin in secondary haemostasis?

<p>Converts fibrinogen into fibrin to form a stable blood clot (C)</p> Signup and view all the answers

What initiates the coagulation pathway in secondary haemostasis?

<p>Synthesis of tissue factor by endothelium (C)</p> Signup and view all the answers

What is the brief period of vasoconstriction at the site of injury due to?

<p>Reflux neurogenic mechanisms (endothelin release) (A)</p> Signup and view all the answers

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