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Non-Protein Nitrogen Compounds in Plasma
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Non-Protein Nitrogen Compounds in Plasma

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Questions and Answers

What is the main reason the term Non-Protein Nitrogen was coined in clinical chemistry?

  • To measure the concentration of ammonia in blood
  • To quantify nitrogen-containing compounds in protein-free filtrates (correct)
  • To analyze urea and creatinine levels in plasma
  • To identify protein degradation by-products
  • Which nitrogen-containing compound is an end-product of nucleic acid catabolism?

  • Creatinine
  • Urea
  • Uric acid (correct)
  • Ammonia
  • What is the primary function of the urea cycle in the liver?

  • To convert urea into ammonia for excretion
  • To produce ammonia from endogenous amino acids
  • To keep ammonia concentrations low by converting it into urea (correct)
  • To facilitate the breakdown of creatinine in plasma
  • Which nitrogen-containing compound has the highest concentration in blood?

    <p>Urea</p> Signup and view all the answers

    How are large amounts of ammonia produced for urea synthesis?

    <p>Through intermediary metabolism of amino acids</p> Signup and view all the answers

    What is the primary reason that Non-Protein Nitrogen (NPN) compounds were quantified spectrophotometrically in clinical chemistry?

    <p>To measure the concentration of nitrogen-containing compounds in a protein-free filtrate</p> Signup and view all the answers

    Which of the following statements about urea is correct?

    <p>Urea is formed in the liver through the urea cycle</p> Signup and view all the answers

    What role does uric acid play in the body?

    <p>Uric acid is involved in nucleic acid catabolism</p> Signup and view all the answers

    How are large amounts of ammonia converted into urea?

    <p>Conversion via a sequence of 5 chemical reactions in the liver</p> Signup and view all the answers

    Which nitrogen-containing compound is considered a protein degradation by-product?

    <p>Creatinine</p> Signup and view all the answers

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