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Non-Protein Nitrogen Compounds in Plasma

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Non-Protein Nitrogen Compounds in Plasma

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Questions and Answers

What is the main reason the term Non-Protein Nitrogen was coined in clinical chemistry?

To measure the concentration of ammonia in blood
To quantify nitrogen-containing compounds in protein-free filtrates (correct)
To analyze urea and creatinine levels in plasma
To identify protein degradation by-products

Which nitrogen-containing compound is an end-product of nucleic acid catabolism?

Creatinine
Urea
Uric acid (correct)
Ammonia

What is the primary function of the urea cycle in the liver?

To convert urea into ammonia for excretion
To produce ammonia from endogenous amino acids
To keep ammonia concentrations low by converting it into urea (correct)
To facilitate the breakdown of creatinine in plasma

Which nitrogen-containing compound has the highest concentration in blood?

Urea (A) Signup and view all the answers

How are large amounts of ammonia produced for urea synthesis?

Through intermediary metabolism of amino acids (B) Signup and view all the answers

What is the primary reason that Non-Protein Nitrogen (NPN) compounds were quantified spectrophotometrically in clinical chemistry?

To measure the concentration of nitrogen-containing compounds in a protein-free filtrate (C) Signup and view all the answers

Which of the following statements about urea is correct?

Urea is formed in the liver through the urea cycle (A) Signup and view all the answers

What role does uric acid play in the body?

Uric acid is involved in nucleic acid catabolism (A) Signup and view all the answers

How are large amounts of ammonia converted into urea?

Conversion via a sequence of 5 chemical reactions in the liver (D) Signup and view all the answers

Which nitrogen-containing compound is considered a protein degradation by-product?

Creatinine (A) Signup and view all the answers