15 Questions
What is the first step of nociception?
Transduction
Where does transmission of neural activation begin in the nociception process?
Dorsal horn of the spinal cord
Which type of fibers are associated with the gray matter laminae in the dorsal horn of the spinal cord?
A beta fibers
What is the role of interneurons in the nociception process?
Modulating sensory input
Where do 2nd order neurons project their input in the nociception process?
Thalamus
What is the function of REXED LAMINAE in the nociception process?
Mediating synapses between 1st and 2nd order neurons
Which part of the nervous system is responsible for sensory modulation and descending inhibition in the nociception process?
Central Nervous System
Which lamina receives presynaptic terminals from A beta neurons?
Lamina 4
Where do second-order neurons associated with nociception direct information from first-order neurons?
Along the spinal cord as part of the spinothalamic tract
Which neurotransmitter is primarily released by first-order C fibers at the synapse junction?
Substance P
What is the primary function of lamina 2, also known as substantia gelatinosa?
Mediates sensory information on slow noxious stimuli
Which ascending pathway carries both noxious and non-noxious information from A beta, A delta, and C-Fibers from the periphery to the thalamus?
Neospinothalamic Tract
Which tract is considered the youngest in terms of biological evolution within the spinothalamic tracts?
Neospinothalamic Tract
What is the primary role of the spinoreticular and spinomesencephalic tracts?
Regulate autonomic responses to nociception
What is the umbrella architectural categorization of sensory pathways that ascend from the spinal cord to the brain?
Anterolateral System
Explore the 5 steps of nociception transmission, including transduction, conduction, transmission, modulation, and perception. Understand the neural activation process, impulse generation, and the role of synapses and neurons in carrying pain, temperature, and other sensory information to the brain.
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