Nobel Prize Discoveries: Artemisia Annua

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Questions and Answers

What innovative treatment for malaria did Tu Youyou discover that led to her Nobel Prize?

  • Artemisinin (correct)
  • Dihydroartemisinin
  • Quinine
  • Avermectin

In what year did Tu Youyou receive the Nobel Prize in Physiology or Medicine?

  • 2015 (correct)
  • 1970
  • 2005
  • 1985

Which derivative of artemisinin is known for its increased potency in treating malaria?

  • Artesunate
  • Artemether
  • Dihydroartemisinin (correct)
  • Chloroquine

What method did Tu Youyou utilize to isolate artemisinin from herbs?

<p>Solvent extraction using water, ethanol, and ethyl ether (D)</p> Signup and view all the answers

Satoshi ÅŒmura's Nobel Prize-winning research focused on discovering which drug?

<p>Ivermectin (C)</p> Signup and view all the answers

Approximately how many people annually benefited from artemisinin-based treatments?

<p>198 Million (A)</p> Signup and view all the answers

Which ancient practice played a key role in Tu Youyou's discovery of artemisinin?

<p>Traditional Chinese herbal medicine (B)</p> Signup and view all the answers

What is the approximate age of the herbal recipes that provided a foundation for Tu Youyou's research?

<p>1600 years (A)</p> Signup and view all the answers

In addition to being the first Chinese woman to win the Nobel Prize in Medicine, what other distinction did Tu Youyou hold?

<p>First person from Mainland China to win the Nobel Prize in Medicine (B)</p> Signup and view all the answers

Flashcards

Artemisinin

A compound discovered by Tu Youyou, effective in treating malaria.

Tu Youyou

Chinese scientist who discovered artemisinin and won the 2015 Nobel Prize.

Nobel Prize in Medicine 2015

Awarded to Tu Youyou for discovery of artemisinin in malaria treatment.

Dihydroartemisinin

A more potent derivative of artemisinin used in malaria treatment.

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Malaria treatment impact

Artemisinin improved success rates in malaria treatments significantly.

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Traditional Chinese medicine

Herbal practices influencing Tu Youyou's artemisinin discovery.

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Combination therapy

Using artemisinin with other drugs for better malaria treatment outcomes.

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Satoshi Omura

Scientist who discovered ivermectin, granted Nobel Prize alongside Tu Youyou.

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Significance of Tu Youyou's work

Showcases how traditional medicine aids modern medical advancements.

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Study Notes

Nobel Prize for Artemisia Annua

  • Awarded to Tu Youyou in 2015
  • Recognized for discovering artemisinin, a life-saving antimalarial drug
  • Was 85 at the time of the award
  • Shared the prize with Satoshi Omura and William C. Campbell

Artemisia Annua Discovery

  • Tu Youyou researched traditional Chinese medicine
  • Investigated Ge Hong's 1600-year-old manuscript on medicinal plants
  • Developed a method of extracting artemisinin from the plant using low temperature ethanol and ethyl ether
  • Tested 240,000+ compounds worldwide prior to the discovery of artemisinin
  • Clinical trials in 1973 and the drug was licensed for use in 1986
  • Discovered a compound that was 10 times more potent than artemisinin

Impact of Discovery

  • 198 million people treated annually with artemisinin combination therapy
  • The combination therapy is used to treat malaria
  • Tu is the first Chinese woman and person to win the Nobel Prize in Medicine

Other Important Figures

  • Satoshi Omura: Japanese biochemist, who used natural substances to discover the drug ivermectin.
  • William C. Campbell: contributed to the development of antiparasitic medicines using natural sources.

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