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WK 4: MRI Basics

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30 Questions

What is the primary reason why MRI does not require labelled probe molecules?

Most elements have at least one NMR sensitive isotope

What is the property of atomic nuclei that NMR and MRI take advantage of?

Magnetic properties

What is the fundamental reason behind the unique sources of contrast in an MRI?

Different spin alignment of atomic nuclei

Why does MRI not require high energy radiation?

Because it uses magnetic fields instead of radiation

What is the significance of spin in NMR and MRI?

It is an intrinsic property of atomic nuclei

What is the main advantage of NMR and MRI over other imaging techniques?

They provide information otherwise unobtainable

Which type of contrast does MRI excel at?

Soft tissue contrast

What is the primary limitation of performing MRI with isotopes other than 1H?

Insufficient signal strength

What happens to the spin alignment when a magnetic field is applied?

The spins align with the magnetic field

Which of the following is NOT a factor affecting the overall sensitivity of a nucleus in MRI?

Patient's body temperature

Why is 1H the isotope of choice for clinical MRI?

It has the highest natural abundance

What is necessary to perform MRI with isotopes of low abundance, such as 13C?

Isotopically labelled samples

What is the typical resolution of high-resolution MRI, also known as 'NMR Microscopy'?

10 μm

What is the main reason to combine MRI with NMR sources of contrast?

To discriminate between different regions of tissue

What is the effect of motion during an MRI imaging sequence?

It causes artifacts in the image

What is the purpose of a Diffusion-MRI pulse sequence?

To measure the diffusion of nuclei

What is the source of contrast in an MRI image?

Any NMR observable with a spatial dependence

What is the effect of chemical shift on the NMR signal?

It causes a small change in resonance frequency

Why are superconducting magnets used in MRI machines?

Because they can be kept at extremely low temperatures

What is the purpose of an oxygen sensor in an MRI facility?

To prevent asphyxiation in case of a magnet quench

What is the effect of increasing B0 on the acquired signal?

The signal becomes stronger

What is the advantage of using an RF coil that is just big enough?

It increases the signal-to-noise ratio

Why are strong magnets required in MRI machines?

To increase the signal-to-noise ratio

What happens to an MRI magnet when it is not in use?

It remains on, even when the machine is turned off

What is the effect of a local distortion of the magnetic field on the MRI image?

It causes some parts of the sample to appear in the wrong place.

What is the purpose of introducing a contrast agent in MRI?

To change the relaxation properties of a specific tissue.

What type of image is obtained when the relaxation properties of the tissue are weighted?

T1-weighted image.

What is the term for the movement of nuclei in a magnetic field?

Precession.

What is the cause of the artifact in the MRI image if the acquisition parameters are improperly set?

Incorrect setting of the imaging pulse sequence.

What is the term for the probability of finding a nucleus in a particular position?

Q-space probability.

Test your knowledge of Nuclear Magnetic Resonance Spectroscopy, a medical imaging technique that utilizes molecular motion. Learn about its advantages, natural abundance, and sensitivity of nuclei.

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