Niosomes in Drug Delivery
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Questions and Answers

What is the advantage of localized drug action achieved through niosomal drug delivery?

  • It enhances the therapeutic index of the drug by increasing its solubility.
  • It allows the drug to penetrate epithelium and connective tissue easily.
  • It facilitates widespread distribution of the drug throughout the body.
  • It confines the drug to the site of administration due to the size and low penetrability of niosomes. (correct)

Which statement about the sustained release action of niosomes is true?

  • It is not suitable for drugs with low solubility in water.
  • It is only effective for drugs with a high therapeutic index.
  • It maintains drugs in circulation via niosomal encapsulation. (correct)
  • It can be applied to highly soluble drugs with a high therapeutic index.

Based on the information provided, what can be inferred about the toxicity of niosomes?

  • There is limited research on the toxicity of niosomes. (correct)
  • Ester type surfactants used in niosomes are more toxic than ether type surfactants.
  • Nasal applications of niosomes are always non-toxic.
  • The physical form of niosomes does not influence their toxicity.

Which characteristic of Spanlastics makes them suitable for transdermal drug delivery?

<p>Their elastic and deformable nature, allowing skin penetration. (D)</p> Signup and view all the answers

What is the primary advantage of using niosomes as hemoglobin carriers?

<p>They can encapsulate and protect hemoglobin from degradation. (A)</p> Signup and view all the answers

Which statement about proniosomes is true based on the given information?

<p>Proniosomes are precursors used to prepare niosomal formulations. (C)</p> Signup and view all the answers

What is one potential application of niosomes as hemoglobin carriers?

<p>Facilitating oxygen transport in the body (A)</p> Signup and view all the answers

What is the major advantage of using niosomes and proniosomes for transdermal drug delivery?

<p>Increased penetration rate through the skin barrier (D)</p> Signup and view all the answers

Which property of niosomes contributes to their potential for sustained release and localized drug action?

<p>Their capacity to encapsulate and slowly release drugs (A)</p> Signup and view all the answers

Which of the following statements about niosomes is true?

<p>They have been shown to improve the anti-inflammatory activity of drugs like diclofenac sodium. (C)</p> Signup and view all the answers

What is one advantage of using niosomes for drug delivery compared to other delivery systems?

<p>Improved stability of the incorporated drug (C)</p> Signup and view all the answers

Which of the following drugs has been studied for delivery using niosomes?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following statements about niosomes is true?

<p>Niosomes are composed of non-ionic surfactants and cholesterol, forming a bilayer structure. (B)</p> Signup and view all the answers

What is a potential advantage of using niosomes for transdermal drug delivery?

<p>Niosomes can enhance drug permeation through the stratum corneum. (C)</p> Signup and view all the answers

Which of the following statements is true regarding the sustained release of drugs using niosomes?

<p>Niosomes can be used to achieve sustained drug release by entrapping drugs within their vesicles. (B)</p> Signup and view all the answers

Which property of niosomes contributes to their potential for localized drug action?

<p>Niosomes can restrict the effects of drugs to target cells or tissues. (A)</p> Signup and view all the answers

Which statement is true regarding the handling and storage of niosomes?

<p>Handling and storage of surfactants used in niosome preparation do not require special conditions. (A)</p> Signup and view all the answers

How can niosomes potentially improve the bioavailability of poorly absorbed drugs?

<p>Niosomes can protect drugs from the biological environment, increasing their bioavailability. (A)</p> Signup and view all the answers
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