Niosomes in Drug Delivery
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Questions and Answers

What is the advantage of localized drug action achieved through niosomal drug delivery?

  • It enhances the therapeutic index of the drug by increasing its solubility.
  • It allows the drug to penetrate epithelium and connective tissue easily.
  • It facilitates widespread distribution of the drug throughout the body.
  • It confines the drug to the site of administration due to the size and low penetrability of niosomes. (correct)

    • Which statement about the sustained release action of niosomes is true?

  • It is not suitable for drugs with low solubility in water.
  • It is only effective for drugs with a high therapeutic index.
  • It maintains drugs in circulation via niosomal encapsulation. (correct)
  • It can be applied to highly soluble drugs with a high therapeutic index.

    • Based on the information provided, what can be inferred about the toxicity of niosomes?

  • There is limited research on the toxicity of niosomes. (correct)
  • Ester type surfactants used in niosomes are more toxic than ether type surfactants.
  • Nasal applications of niosomes are always non-toxic.
  • The physical form of niosomes does not influence their toxicity.

    • Which characteristic of Spanlastics makes them suitable for transdermal drug delivery?

    <p>Their elastic and deformable nature, allowing skin penetration.</p> Signup and view all the answers

    What is the primary advantage of using niosomes as hemoglobin carriers?

    <p>They can encapsulate and protect hemoglobin from degradation.</p> Signup and view all the answers

    Which statement about proniosomes is true based on the given information?

    <p>Proniosomes are precursors used to prepare niosomal formulations.</p> Signup and view all the answers

    What is one potential application of niosomes as hemoglobin carriers?

    <p>Facilitating oxygen transport in the body</p> Signup and view all the answers

    What is the major advantage of using niosomes and proniosomes for transdermal drug delivery?

    <p>Increased penetration rate through the skin barrier</p> Signup and view all the answers

    Which property of niosomes contributes to their potential for sustained release and localized drug action?

    <p>Their capacity to encapsulate and slowly release drugs</p> Signup and view all the answers

    Which of the following statements about niosomes is true?

    <p>They have been shown to improve the anti-inflammatory activity of drugs like diclofenac sodium.</p> Signup and view all the answers

    What is one advantage of using niosomes for drug delivery compared to other delivery systems?

    <p>Improved stability of the incorporated drug</p> Signup and view all the answers

    Which of the following drugs has been studied for delivery using niosomes?

    <p>All of the above</p> Signup and view all the answers

    Which of the following statements about niosomes is true?

    <p>Niosomes are composed of non-ionic surfactants and cholesterol, forming a bilayer structure.</p> Signup and view all the answers

    What is a potential advantage of using niosomes for transdermal drug delivery?

    <p>Niosomes can enhance drug permeation through the stratum corneum.</p> Signup and view all the answers

    Which of the following statements is true regarding the sustained release of drugs using niosomes?

    <p>Niosomes can be used to achieve sustained drug release by entrapping drugs within their vesicles.</p> Signup and view all the answers

    Which property of niosomes contributes to their potential for localized drug action?

    <p>Niosomes can restrict the effects of drugs to target cells or tissues.</p> Signup and view all the answers

    Which statement is true regarding the handling and storage of niosomes?

    <p>Handling and storage of surfactants used in niosome preparation do not require special conditions.</p> Signup and view all the answers

    How can niosomes potentially improve the bioavailability of poorly absorbed drugs?

    <p>Niosomes can protect drugs from the biological environment, increasing their bioavailability.</p> Signup and view all the answers

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