Nicoderm CQ Review Questions

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What is the primary mechanism of drug release in the PROCARDIA XL Extended Release Tablet?

Osmotic pressure-controlled release (correct)
pH-dependent release
Swelling-controlled release
Diffusion-controlled release

What is the function of the 'push' layer in the PROCARDIA XL tablet?

To create an osmotic gradient that drives drug release (correct)
To control the pH-dependent solubility of the drug
To provide an immediate release of the drug
To prevent degradation of the drug in the gastrointestinal tract

How does the NicoDerm CQ patch help prevent the urge to smoke?

It contains a slow-release formulation of nicotine
It releases nicotine based on the user's smoking patterns
It uses a unique technology to control nicotine delivery (correct)
It provides a constant level of nicotine to the body

What is the purpose of the laser-drilled orifice in the PROCARDIA XL tablet?

To control the rate of drug release from the tablet (C) Signup and view all the answers

What is the primary purpose of the flavored and sweetened base in lozenges?

To mask the bitter taste of the active ingredient (D) Signup and view all the answers

What is the purpose of the biologically inert components in the PROCARDIA XL tablet?

To maintain the structural integrity of the tablet during gastrointestinal transit (A) Signup and view all the answers

What is the primary mechanism of action for hydrophilic spherical vesicles with a phospholipid bilayer?

Unmodified liposomes gather in specific tissue reticulo-endothelial system (B) Signup and view all the answers

What is the key feature of the PROCARDIA XL® Extended Release Tablet?

It is similar in appearance to a conventional tablet (C) Signup and view all the answers

Which of the following is NOT an inert ingredient in the PROCARDIA capsule formulation?

Nifedipine (A) Signup and view all the answers

What is the key difference between a prodrug and an active drug?

Prodrugs are usually inactive compared to the release drugs (A) Signup and view all the answers

What is the primary mechanism of action for the NicoDerm CQ with SmartControl® Technology?

It is not provided in the information given (A) Signup and view all the answers

What is the primary purpose of using lozenges as a solid oral dosage form?

To allow for slow dissolution and local drug delivery in the mouth (C) Signup and view all the answers

Which of the following is a characteristic of osmotic pump drug delivery systems?

The drug is released by diffusion through a semipermeable membrane (A) Signup and view all the answers

What is the primary advantage of the NicoDerm CQ patch with SmartControl® Technology?

It has a unique delivery system that adjusts the nicotine release rate based on cravings (D) Signup and view all the answers

Which of the following is a characteristic of lozenges as a solid oral dosage form?

They are intended to dissolve or disintegrate slowly in the mouth (B) Signup and view all the answers

What is the primary advantage of the extended-release tablet formulation of Procardia XL?

It allows for once-daily dosing, improving patient compliance (B) Signup and view all the answers

Which of the following is a characteristic of liposomes as a drug delivery system?

They are composed of a lipid bilayer surrounding an aqueous core (D) Signup and view all the answers

Which of the following statements about amorphous drug delivery systems is true?

They can improve the dissolution rate and bioavailability of poorly soluble drugs (B) Signup and view all the answers