8 Questions
What is the mechanism of sensitization to nickel?
Dendritic cells in the skin internalize and process epicutaneously applied hapten and migrate to the lymph nodes
What is the consequence of asbestos fibers diffusing into the pulmonary alveoli?
Release of ROS including OH. from H2O2 by Fenton Reaction
How do asbestos fibers damage DNA?
Through ROS reactions producing hydroxyl bases and causing mutations
What is the main effect of asbestos on mesothelium cell proliferation?
Disruption of MARK activity involved in regulation of cell proliferation
What is the result of asbestos inhalation on lung health?
Lung fibrosis, lung carcinoma, or mesothelioma
Which biotechnology-based medicine is associated with autoimmune aplasia?
Recombinant human erythropoietin
Which medicine is linked to autoimmune hepatitis?
Anti-TNF-α
Which autoimmune reaction is associated with Etanercept, infliximab, and adalimumab?
Lupus syndrome
Test your knowledge about the immunotoxic effects of nickel and how it causes contact dermatitis. Explore the process of sensitization and T cell activation upon re-exposure to the antigen.
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