Neurotransmitters & Mental Disorders
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Questions and Answers

What is the primary function of agonist drugs?

  • They have no effect on neurotransmission.
  • They increase the effects of specific neurotransmitters. (correct)
  • They decrease the levels of specific neurotransmitters.
  • They block neurotransmission entirely.
  • How do direct-acting drugs influence neurotransmission?

  • They directly interact with synaptic receptors.
  • They block the enzymes that break down neurotransmitters.
  • They mimic neurotransmitters due to similar chemical structures. (correct)
  • They inhibit the uptake of neurotransmitters.
  • Which of the following describes the action of cocaine?

  • It blocks the absorption of acetylcholine.
  • It is an indirect-acting drug influencing dopamine transmission. (correct)
  • It is a direct-acting agonist for serotonin.
  • It acts as a cholinesterase inhibitor.
  • What effect do selective serotonin reuptake inhibitors (SSRIs) have on serotonin levels?

    <p>They inhibit the absorption of serotonin by nerve cells.</p> Signup and view all the answers

    Which type of drugs block the effects of neurotransmission?

    <p>Antagonists</p> Signup and view all the answers

    What can happen if neurons do not manufacture enough of a particular neurotransmitter?

    <p>Loss of memory and learning ability</p> Signup and view all the answers

    Which neurotransmitter is associated with mood disorders such as depression?

    <p>Serotonin</p> Signup and view all the answers

    What condition may result from too much norepinephrine activity?

    <p>Mania</p> Signup and view all the answers

    Which neurotransmitter's deficiency is linked to Alzheimer's disease?

    <p>Acetylcholine</p> Signup and view all the answers

    How can drugs that affect neurotransmitters help patients?

    <p>They change the action of neurotransmitters to alleviate symptoms.</p> Signup and view all the answers

    What possible effect does an increase in glutamate activity have?

    <p>Seizures due to high-frequency firing of neurons</p> Signup and view all the answers

    Which neurotransmitter is linked with addiction and schizophrenia?

    <p>Dopamine</p> Signup and view all the answers

    What can rapid reabsorption of neurotransmitters potentially cause?

    <p>Decreased neuronal signaling</p> Signup and view all the answers

    Study Notes

    Neurotransmitters & Mental Disorders

    • Neurotransmitters can malfunction in various ways, such as insufficient production, rapid reabsorption, excessive enzyme deactivation, or over-release.
    • Imbalances in neurotransmitters contribute to various diseases like Alzheimer's, epilepsy, and Parkinson's.
    • Certain neurotransmitters, often called "feel-good" chemicals, influence mood, including dopamine, serotonin, oxytocin, norepinephrine, and endorphins.
    • Medications that alter neurotransmitter activity are often prescribed to treat psychiatric conditions.
    • Dopamine is linked to addiction and schizophrenia.
    • Serotonin is associated with mood disorders (e.g., depression, OCD).
    • Dopamine, GABA, serotonin, and norepinephrine are connected to anxiety disorders.
    • Insufficient acetylcholine is a factor in Alzheimer's disease memory loss.
    • Excessive serotonin may be related to autism spectrum disorder.
    • Increased glutamate activity or reduced GABA activity can cause seizures.
    • Excessive norepinephrine and dopamine activity, along with abnormal glutamate transmission, contribute to mania.

    Drugs Affecting Neurotransmitters

    • Agonists increase neurotransmitter effects.
    • Antagonists block neurotransmitter effects.
    • Direct-acting drugs mimic neurotransmitters in structure to bind to and stimulate receptors.
    • Indirect-acting drugs influence neurotransmitter activity by acting on synaptic receptors.
    • Medications for conditions like depression and anxiety (SSRIs, tricyclic antidepressants, benzodiazepines) influence neurotransmitters.
    • SSRIs (e.g., Prozac, Paxil) increase serotonin levels by blocking serotonin reuptake.
    • Cholinesterase inhibitors (e.g., Aricept) prevent the breakdown of acetylcholine, potentially improving cognitive function in Alzheimer's.
    • Illicit drugs like heroin, cocaine, and marijuana also impact neurotransmission. Heroin acts as a direct-acting agonist mimicking opioids, while cocaine influences dopamine transmission indirectly.

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    Description

    Explore the critical role of neurotransmitters in mental health through this quiz. Learn about their impact on conditions like depression, anxiety, and Alzheimer's disease, as well as the feel-good chemicals that influence mood. Dive into how imbalances can lead to mental disorders and the medications used to correct these issues.

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