Neurotransmitters and Schizophrenia

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Which program targets individuals experiencing their first episode of psychosis and includes family education, individual resiliency training, supported employment and education, and individualized medication treatment?

NAVIGATE

What is the diagnosis that requires concurrent symptoms of schizophrenia and a major depressive or manic episode, with the presence of delusions or hallucinations for two or more weeks without mood symptoms?

Schizoaffective Disorder

What is the diagnosis that requires the person to have one or more delusions for a duration of at least one month, with overall functioning not markedly impaired except for any direct effects of the delusion?

Delusional Disorder

Which neurotransmitters have been linked to schizophrenia?

Dopamine, glutamate, and serotonin

What is the revised version of the dopamine hypothesis of schizophrenia?

Positive symptoms are due to dopamine hyperactivity in subcortical regions, while negative symptoms are due to dopamine hypoactivity in cortical regions

What brain abnormalities are associated with schizophrenia?

Enlarged ventricles and hypofrontality

According to the DSM-5-TR, what percentage of individuals with schizophrenia are tobacco users?

70 to 85%

At what age do the psychotic symptoms of schizophrenia usually first appear?

Late teens to early 30s

Which factor is associated with a better prognosis for schizophrenia?

Lack of comorbid mood symptoms

Which antipsychotic drug has been found to be the most effective for treatment-resistant schizophrenia?

Clozapine

Which neurotransmitters have been linked to schizophrenia?

Dopamine, glutamate, and serotonin

What is the revised version of the dopamine hypothesis of schizophrenia?

The positive symptoms of schizophrenia are due to dopamine hyperactivity in subcortical regions of the brain, while the negative symptoms are due to dopamine hypoactivity in cortical regions

What brain abnormalities are associated with schizophrenia?

Enlarged ventricles and hypofrontality

Which program provides individualized resiliency training based on CBTp to help patients manage their illness?

NAVIGATE

What is the diagnosis that requires concurrent symptoms of schizophrenia and a major depressive or manic episode, with the presence of delusions or hallucinations for two or more weeks without mood symptoms?

Schizoaffective Disorder

What is the diagnosis that requires the person to have one or more delusions for a duration of at least one month, with overall functioning not markedly impaired except for any direct effects of the delusion?

Delusional Disorder

Which age group has the highest peak age of onset for psychotic symptoms of schizophrenia?

Early- to mid-20s for males and late-20s for females

Which country group is more likely to experience an acute onset of symptoms, a shorter course, and a higher rate of remission in schizophrenia?

Non-Western developing countries

What is anosognosia associated with in patients with schizophrenia?

Non-adherence to treatment and risk for relapse

What is the "immigrant paradox" in relation to schizophrenia?

Acculturated immigrants have better health outcomes than newly arrived immigrants

Which neurotransmitter is believed to contribute to the positive symptoms of schizophrenia?

Dopamine

What is hypofrontality in relation to schizophrenia?

Lower-than-normal activity in the prefrontal cortex

Which brain regions are implicated in the dysfunction associated with the negative symptoms of schizophrenia?

Cortical regions

Which program provides individualized resiliency training based on CBTp to help patients manage their illness?

NAVIGATE

What is the diagnosis that requires concurrent symptoms of schizophrenia and a major depressive or manic episode, with the presence of delusions or hallucinations for two or more weeks without mood symptoms?

Schizoaffective Disorder

What is the diagnosis that requires the person to have one or more delusions for a duration of at least one month, with overall functioning not markedly impaired except for any direct effects of the delusion?

Delusional Disorder

Which gender has a better prognosis for schizophrenia?

Females

What is expressed emotion in the context of schizophrenia?

A family member's emotional response to a patient with schizophrenia

Which antipsychotic drug is considered the most effective for treatment-resistant schizophrenia?

Clozapine

What is the "immigrant paradox" in relation to schizophrenia?

Newly arrived immigrants have better health outcomes than acculturated immigrants

Test your knowledge on neurotransmitters linked to schizophrenia and the original dopamine hypothesis. Learn about the role of dopamine, glutamate, and serotonin, and the evidence supporting the hypothesis. Explore the effects of amphetamines and other drugs on dopamine activity and symptoms associated with schizophrenia.

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