18 Questions
What is the function of cocaine in relation to neurotransmitter reuptake?
Inactivate transporters responsible for reuptake
Which type of neurotransmitter has an inhibitory effect in the brain?
GABA
How are molecules of neurotransmitter removed from the synapse?
By reuptake into the presynaptic cell
Which category of drugs blocks reuptake of neurotransmitters?
Agonists
What is the primary role of serotonin transporters?
Reuptake serotonin into the presynaptic cell
What effect do indirect agonists have on neurotransmitters?
Act on alternative binding sites
What is the role of antagonists in synaptic transmission?
Inhibit postsynaptic effects
Which step involves the entry of calcium ions in synaptic activity?
Firing of axon leading to opening of voltage-dependent calcium channels
How do precursor drugs affect the neurotransmitter system?
Increase activity of the neurotransmitter system
Which drugs are considered antagonists?
Drugs that block neurotransmitter effects
What role do transporter molecules play in synaptic transmission?
Facilitate reuptake of neurotransmitters
How do drugs that deactivate enzymes impact synaptic transmission?
Prevent the production of neurotransmitters
Which type of drug binds with a particular site on vesicle transporters to block them and inactivate their function?
Direct antagonist
What is the main difference between vesicle transporters and terminal membrane transporters in neurotransmitter storage and release?
Vesicle transporters pump molecules into synaptic vesicles, while terminal membrane transporters move molecules from synapse to cytoplasm.
Which drug action involves binding to an alternative site and facilitating ion channel opening?
Indirect agonist
What does Botulinum toxin (Botox) primarily affect in terms of neurotransmitter function?
Prevents the release of acetylcholine
Which type of drug binds with a receptor but does not activate it, preventing the natural ligand from binding with the receptor?
Direct antagonist
How do vesicle transporters differ from terminal membrane transporters in synaptic transmission?
Vesicle transporters pump neurotransmitters into vesicles, while terminal membrane transporters move them into the cytoplasm.
Test your knowledge on the processes involved in removing neurotransmitters from the synapse and the effects of noncompetitive binding by indirect agonists and antagonists. Learn about reuptake and enzymatic deactivation of neurotransmitters.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
