PSYC 21 | Drugs Multiple Choice

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What is the function of cocaine in relation to neurotransmitter reuptake?

Promote neurotransmitter synthesis

Increase neurotransmitter destruction

Stimulate neurotransmitter release

Inactivate transporters responsible for reuptake (correct)

Which type of neurotransmitter has an inhibitory effect in the brain?

Glutamate

GABA (correct)

Serotonin

Histamine

How are molecules of neurotransmitter removed from the synapse?

By enzymatic deactivation

By reuptake into the presynaptic cell (correct)

By breakdown in the postsynaptic cell

By diffusion into the bloodstream

Which category of drugs blocks reuptake of neurotransmitters?

Agonists Signup and view all the answers

What is the primary role of serotonin transporters?

Reuptake serotonin into the presynaptic cell Signup and view all the answers

What effect do indirect agonists have on neurotransmitters?

Act on alternative binding sites Signup and view all the answers

What is the role of antagonists in synaptic transmission?

Inhibit postsynaptic effects Signup and view all the answers

Which step involves the entry of calcium ions in synaptic activity?

Firing of axon leading to opening of voltage-dependent calcium channels Signup and view all the answers

How do precursor drugs affect the neurotransmitter system?

Increase activity of the neurotransmitter system Signup and view all the answers

Which drugs are considered antagonists?

Drugs that block neurotransmitter effects Signup and view all the answers

What role do transporter molecules play in synaptic transmission?

Facilitate reuptake of neurotransmitters Signup and view all the answers

How do drugs that deactivate enzymes impact synaptic transmission?

Prevent the production of neurotransmitters Signup and view all the answers

Which type of drug binds with a particular site on vesicle transporters to block them and inactivate their function?

Direct antagonist Signup and view all the answers

What is the main difference between vesicle transporters and terminal membrane transporters in neurotransmitter storage and release?

Vesicle transporters pump molecules into synaptic vesicles, while terminal membrane transporters move molecules from synapse to cytoplasm. Signup and view all the answers

Which drug action involves binding to an alternative site and facilitating ion channel opening?

Indirect agonist Signup and view all the answers

What does Botulinum toxin (Botox) primarily affect in terms of neurotransmitter function?

Prevents the release of acetylcholine Signup and view all the answers

Which type of drug binds with a receptor but does not activate it, preventing the natural ligand from binding with the receptor?

Direct antagonist Signup and view all the answers

How do vesicle transporters differ from terminal membrane transporters in synaptic transmission?

Vesicle transporters pump neurotransmitters into vesicles, while terminal membrane transporters move them into the cytoplasm. Signup and view all the answers