PSYC 21 | Drugs Multiple Choice

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Questions and Answers

What is the function of cocaine in relation to neurotransmitter reuptake?

  • Promote neurotransmitter synthesis
  • Increase neurotransmitter destruction
  • Stimulate neurotransmitter release
  • Inactivate transporters responsible for reuptake (correct)

Which type of neurotransmitter has an inhibitory effect in the brain?

  • Glutamate
  • GABA (correct)
  • Serotonin
  • Histamine

How are molecules of neurotransmitter removed from the synapse?

  • By enzymatic deactivation
  • By reuptake into the presynaptic cell (correct)
  • By breakdown in the postsynaptic cell
  • By diffusion into the bloodstream

Which category of drugs blocks reuptake of neurotransmitters?

<p>Agonists (B)</p> Signup and view all the answers

What is the primary role of serotonin transporters?

<p>Reuptake serotonin into the presynaptic cell (B)</p> Signup and view all the answers

What effect do indirect agonists have on neurotransmitters?

<p>Act on alternative binding sites (C)</p> Signup and view all the answers

What is the role of antagonists in synaptic transmission?

<p>Inhibit postsynaptic effects (B)</p> Signup and view all the answers

Which step involves the entry of calcium ions in synaptic activity?

<p>Firing of axon leading to opening of voltage-dependent calcium channels (A)</p> Signup and view all the answers

How do precursor drugs affect the neurotransmitter system?

<p>Increase activity of the neurotransmitter system (D)</p> Signup and view all the answers

Which drugs are considered antagonists?

<p>Drugs that block neurotransmitter effects (D)</p> Signup and view all the answers

What role do transporter molecules play in synaptic transmission?

<p>Facilitate reuptake of neurotransmitters (B)</p> Signup and view all the answers

How do drugs that deactivate enzymes impact synaptic transmission?

<p>Prevent the production of neurotransmitters (B)</p> Signup and view all the answers

Which type of drug binds with a particular site on vesicle transporters to block them and inactivate their function?

<p>Direct antagonist (C)</p> Signup and view all the answers

What is the main difference between vesicle transporters and terminal membrane transporters in neurotransmitter storage and release?

<p>Vesicle transporters pump molecules into synaptic vesicles, while terminal membrane transporters move molecules from synapse to cytoplasm. (A)</p> Signup and view all the answers

Which drug action involves binding to an alternative site and facilitating ion channel opening?

<p>Indirect agonist (B)</p> Signup and view all the answers

What does Botulinum toxin (Botox) primarily affect in terms of neurotransmitter function?

<p>Prevents the release of acetylcholine (D)</p> Signup and view all the answers

Which type of drug binds with a receptor but does not activate it, preventing the natural ligand from binding with the receptor?

<p>Direct antagonist (D)</p> Signup and view all the answers

How do vesicle transporters differ from terminal membrane transporters in synaptic transmission?

<p>Vesicle transporters pump neurotransmitters into vesicles, while terminal membrane transporters move them into the cytoplasm. (A)</p> Signup and view all the answers

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