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Questions and Answers
A drug that inhibits the storage of neurotransmitters within synaptic vesicles would directly affect which aspect of neurotransmitter function?
A drug that inhibits the storage of neurotransmitters within synaptic vesicles would directly affect which aspect of neurotransmitter function?
- Transmitter reuptake into the presynaptic neuron
- Transmitter clearance from the synaptic cleft
- Transmitter release into the synaptic cleft (correct)
- Transmitter synthesis within the neuron
How would a medication that blocks axonal transport most likely impact neurotransmission?
How would a medication that blocks axonal transport most likely impact neurotransmission?
- By reducing the supply of neurotransmitters to the presynaptic terminal. (correct)
- By preventing the degradation of neurotransmitters in the synapse.
- By preventing the synthesis of neurotransmitters.
- By directly interfering with the postsynaptic receptors.
Which mechanism of action would be most effective in prolonging the effect of a neurotransmitter in the synaptic cleft?
Which mechanism of action would be most effective in prolonging the effect of a neurotransmitter in the synaptic cleft?
- Enhancing the activity of enzymes that degrade the neurotransmitter.
- Blocking the reuptake transporters for the neurotransmitter. (correct)
- Increasing the rate of neurotransmitter synthesis.
- Enhancing the storage of neurotransmitters in vesicles.
If a toxin prevents synaptic transmission by interfering with calcium channel function at the presynaptic terminal, what specific process is being directly disrupted?
If a toxin prevents synaptic transmission by interfering with calcium channel function at the presynaptic terminal, what specific process is being directly disrupted?
A drug that enhances presynaptic activity leads to increased neurotransmitter release. Which downstream effect would NOT be expected as a direct result of this drug's mechanism?
A drug that enhances presynaptic activity leads to increased neurotransmitter release. Which downstream effect would NOT be expected as a direct result of this drug's mechanism?
Flashcards
Inhibition of transmitter synthesis
Inhibition of transmitter synthesis
Drugs can reduce neurotransmitter levels by stopping their creation.
Blockade of axonal transport
Blockade of axonal transport
Some drugs block the movement of neurotransmitters down the axon.
Interference With Transmitter Storage
Interference With Transmitter Storage
Drugs can interfere with how neurotransmitters are stored in vesicles.
Prevention of Synaptic Transmission
Prevention of Synaptic Transmission
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Inactivation of transmitter reuptake
Inactivation of transmitter reuptake
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Study Notes
Effects on transmitter production
- Transmitter production can be impacted through inhibition of transmitter synthesis.
- Transmitter production can be impaired by blockade of axonal transport.
- Transmitter production can be affected by interference with the storage of transmitters.
Effects on transmitter release
- Synaptic transmission can be prevented.
- Synaptic transmitter release can be altered through calcium channel blockade.
- Synaptic transmitter release can be altered through modulation of presynaptic activity.
- Synaptic transmitter release can be altered through other mechanisms.
Effects on transmitter clearance
- Transmitter clearance can be affected by Inactivation of transmitter reuptake.
- Transmitter clearance can be affected by Blockade of transmitter degradation.
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