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Questions and Answers
What is a primary indication for using a CT scan in neurosurgery?
What is a primary indication for using a CT scan in neurosurgery?
Which condition is best assessed using an MRI rather than a CT scan?
Which condition is best assessed using an MRI rather than a CT scan?
What is a contraindication for performing an MRI?
What is a contraindication for performing an MRI?
Which imaging technique is preferred for diagnosing bone-related pathologies?
Which imaging technique is preferred for diagnosing bone-related pathologies?
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What is a primary purpose of diagnostic techniques in neurosurgery?
What is a primary purpose of diagnostic techniques in neurosurgery?
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How soon can infarction be diagnosed using an MRI compared to a CT scan?
How soon can infarction be diagnosed using an MRI compared to a CT scan?
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Which of the following properties is essential for a diagnostic tool in neurosurgery?
Which of the following properties is essential for a diagnostic tool in neurosurgery?
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What is the primary purpose of a positron emission tomography (PET) scan?
What is the primary purpose of a positron emission tomography (PET) scan?
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Which condition is a contraindication for lumbar puncture?
Which condition is a contraindication for lumbar puncture?
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Which condition would be diagnosed using a CT scan rather than an MRI?
Which condition would be diagnosed using a CT scan rather than an MRI?
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What classification category does a magnetic resonance imaging (MRI) fall under?
What classification category does a magnetic resonance imaging (MRI) fall under?
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Which investigation is most likely to show evidence of metastatic tumors?
Which investigation is most likely to show evidence of metastatic tumors?
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What is a common disadvantage of using MRI compared to CT scans?
What is a common disadvantage of using MRI compared to CT scans?
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What is one indication for performing a lumbar puncture?
What is one indication for performing a lumbar puncture?
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Which of the following is NOT a major abnormality to look for on a plain skull X-ray?
Which of the following is NOT a major abnormality to look for on a plain skull X-ray?
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What is typically NOT evaluated during the assessment of a plain X-ray of the spine?
What is typically NOT evaluated during the assessment of a plain X-ray of the spine?
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Which of the following is a key feature to check when analyzing plain X-rays of the spine?
Which of the following is a key feature to check when analyzing plain X-rays of the spine?
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What is the purpose of a cerebrospinal fluid analysis within non-radiological investigations?
What is the purpose of a cerebrospinal fluid analysis within non-radiological investigations?
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What is a complication associated with lumbar puncture?
What is a complication associated with lumbar puncture?
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Which diagnostic tool is most suitable for a study of carotid blood flow?
Which diagnostic tool is most suitable for a study of carotid blood flow?
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What is the purpose of measuring intracranial pressure?
What is the purpose of measuring intracranial pressure?
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Which of the following is an advantage of ultrasound scanning?
Which of the following is an advantage of ultrasound scanning?
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Which tumor markers are typically associated with tumors in the pineal region?
Which tumor markers are typically associated with tumors in the pineal region?
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What risk is increased in patients with a bleeding tendency who undergo lumbar puncture?
What risk is increased in patients with a bleeding tendency who undergo lumbar puncture?
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Study Notes
Introduction
- Diagnostic techniques in neurosurgery have advanced with technological breakthroughs.
- These tests are used to screen, confirm diagnoses, and assist in treatment planning.
- Clinical acumen is still crucial.
Diagnosis
- A combination of history, examination, and investigation is necessary for diagnosis.
Properties of a Diagnostic Tool
- Easy to use
- Non-harmful, non-carcinogenic, and non-allergic.
- 100% sensitive and 100% specific.
- No ideal radiological tool exists.
Classification of Diagnostic Techniques
- Radiological: Plain X-ray, ultrasound scan, computed tomography (CT) scan, magnetic resonance imaging (MRI), positron emission tomography (PET), radionuclide study.
- Non-radiological: Cerebrospinal fluid analysis, hormonal assay, tumor markers, nerve conduction studies.
Plain X-Ray
- Common investigation.
- Useful for identifying fractures, dislocations, deformities, and infections.
- Skull and spine X-rays are frequently requested.
- Skull X-rays: AP and lateral views.
- Spine X-rays: Cervical, thoracic, and lumbosacral spines.
- Abnormalities to look for on skull X-ray include: linear or depressed fractures.
Computed Tomography (CT) Scan
- Indications:
- Diagnosis of acute neurosurgical lesions in the head and spine, including skull and spinal fractures.
- Intracranial hemorrhage (extradural hematoma, subdural hematoma, intracerebral hematoma).
- Brain edema (due to trauma or other causes).
- Mass lesions, such as tumors and brain abscesses.
- Hydrocephalus.
- Stroke.
- Advantages:
- Better than MRI for diagnosing bone-related pathologies like fractures and bone tumors.
- Better for acute hemorrhagic lesions.
- Faster than MRI (few minutes), making it suitable for critically ill patients.
- Disadvantages:
- Uses ionizing radiation.
Magnetic Resonance Imaging (MRI)
- Indications:
- Intracranial tumors.
- Cerebral abscess.
- Arteriovenous malformations.
- Venous sinus thrombosis.
- Craniospinal abnormalities, such as the Chiari malformation.
- Syringomyelia.
- Spinal tumors.
- Disc prolapse (cervical, lumbar, and dorsal).
- Spinal canal stenosis (lumbar or cervical stenosis) and cervical myelopathy.
- Advantages:
- Superior to CT for sellar pathology (pituitary), posterior fossa tumors (cerebellar and brainstem tumors), and spinal cord pathology.
- Non-invasive myelography capability.
- Can diagnose infarction within a few hours.
- No ionizing radiation, allowing for safe repetition.
- Disadvantages:
- Metallic foreign bodies in the body (plating and screwing, shells, cardiac pacemakers, intracranial clips) can interfere with MRI.
- Claustrophobia.
- Gross obesity.
- Uncontrolled movement disorders (Parkinson's disease).
- Respiratory disease requiring assisted ventilation or carrying risk of apnea.
Positron Emission Tomography (PET) Scan
- Used to map tissue biochemistry and physiology (functional test).
- Commonly used PET tracer is labeled glucose (Fludeoxyglucose (18F) (FDG).
- Useful in differentiating ischemic from neoplastic areas.
Cranial and Spinal Angiography
- Provides images of blood vessels.
- Used to diagnose:
- Arteriovenous malformations.
- Intracranial aneurysms.
Ultrasound Scan (USS)
- Transfontanelle USS:
- Detects hydrocephalus and intracranial bleeds.
- Doppler Scan:
- Used for carotid studies.
- Advantages:
- Simple, fast, and non-radiation based.
- Disadvantages:
- Observer-dependent.
Non-Radiological Techniques
Cerebrospinal Fluid (CSF) Investigation
- CSF can be obtained through spinal or cranial punctures.
- Spinal puncture (lumbar puncture): Most safely accessed in the lumbar cistern, where the spinal cord ends in the cauda equina (between the first and second lumbar vertebrae).
- Indications:
- Suspected meningitis.
- Subarachnoid hemorrhage (SAH).
- Cytology in neoplastic diseases.
- Measurement of intracranial pressure (ICP).
- Therapeutic CSF aspiration (pseudotumor cerebri).
- Conventional myelography via contrast injection.
- Spinal anesthesia.
Lumbar Puncture
- Indications:
- Suspected meningitis.
- Subarachnoid hemorrhage (SAH).
- Cytology in neoplastic diseases.
- Measurement of intracranial pressure (ICP).
- Therapeutic CSF aspiration (pseudotumor cerebri).
- Conventional myelography via contrast injection.
- Spinal anesthesia.
- Contraindications:
- Raised intracranial pressure (except pseudotumor cerebri).
- Features suggestive of raised ICP, including focal neurological deficit, recent seizure, papilloedema.
- Sepsis at the site of the LP.
- Bleeding tendency (coagulopathy and thrombocytopenia).
- Abnormal respiration.
- Vertebral deformities (kyphosis and scoliosis).
- Total spinal block.
- Obstructive hydrocephalus.
- Complications:
- Post-spinal headache.
- Cerebellar tonsillar herniation (if there is raised ICP).
- Injury to neural structures.
- Back pain.
- Infection and meningitis.
- Implantation of cutaneous tissue, leading to an epidermoid cyst.
- Bleeding.
- Measurement of intracranial pressure.
Hormonal Studies
- Used to investigate sellar and parasellar pathologies (pituitary tumors, craniopharyngioma, tuberculum sellar meningioma).
- Hormones measured:
- Prolactin.
- ACTH.
- Cortisol.
- TSH, T3, T4.
- GH.
Tumor Markers
- Used in pineal region tumors.
- Markers measured:
- Beta-HCG.
- Alpha fetoprotein.
- Placental alkaline phosphatase.
Conclusion
- Diagnostic tests are essential for managing patients in neurosurgery.
- A combination of history, examination, and investigation is crucial for reaching a diagnosis.
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Description
Explore the advancements and classifications of diagnostic techniques in neurosurgery. This quiz covers various diagnostic tools, including radiological and non-radiological methods, their properties, and the importance of clinical acumen in diagnosis and treatment planning.