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Questions and Answers
What primarily differentiates functional magnetic resonance imaging (fMRI) from traditional MRI?
What primarily differentiates functional magnetic resonance imaging (fMRI) from traditional MRI?
- fMRI is used exclusively for spinal cord analysis.
- fMRI measures brain structure.
- fMRI provides a static image of the brain.
- fMRI detects changes associated with blood flow. (correct)
Which structure is responsible for serving as a link between the brain and the rest of the body?
Which structure is responsible for serving as a link between the brain and the rest of the body?
- Peripheral nerves
- Cerebellum
- Spinal cord (correct)
- Cerebrum
Which components of the spinal cord carry signals from the brain to the spinal nerves?
Which components of the spinal cord carry signals from the brain to the spinal nerves?
- Ascending tracts
- Descending tracts (correct)
- Cervical nerves
- Efferent fibers
What is the primary function of afferent fibers in the spinal cord?
What is the primary function of afferent fibers in the spinal cord?
Which statement about nerves and neurons is accurate?
Which statement about nerves and neurons is accurate?
What structure is mainly responsible for the formation of the blood-brain barrier (BBB)?
What structure is mainly responsible for the formation of the blood-brain barrier (BBB)?
Where is the gray matter located in the spinal cord?
Where is the gray matter located in the spinal cord?
What is the role of cerebrospinal fluid (CSF)?
What is the role of cerebrospinal fluid (CSF)?
Which type of neuron has a single axon and is often fused with its dendrite?
Which type of neuron has a single axon and is often fused with its dendrite?
Which area of the brain is primarily involved in language comprehension?
Which area of the brain is primarily involved in language comprehension?
Which of the following components are part of the protective structures of the central nervous system?
Which of the following components are part of the protective structures of the central nervous system?
What type of fluid is found in the brain's ventricles and protects the brain during sudden movements?
What type of fluid is found in the brain's ventricles and protects the brain during sudden movements?
What term describes the uneven distribution of sensory and motor cortex areas depicted in the homunculus?
What term describes the uneven distribution of sensory and motor cortex areas depicted in the homunculus?
Which type of glial cell is primarily involved in the maintenance and repair of neural tissue?
Which type of glial cell is primarily involved in the maintenance and repair of neural tissue?
Which division of the peripheral nervous system is responsible for voluntary actions?
Which division of the peripheral nervous system is responsible for voluntary actions?
What is the main function of the cerebellum?
What is the main function of the cerebellum?
What is the primary role of oligodendrocytes in the nervous system?
What is the primary role of oligodendrocytes in the nervous system?
What is a major characteristic of the cerebral cortex?
What is a major characteristic of the cerebral cortex?
What is temporal summation primarily characterized by?
What is temporal summation primarily characterized by?
Which process involves multiple presynaptic inputs influencing a single postsynaptic neuron?
Which process involves multiple presynaptic inputs influencing a single postsynaptic neuron?
What is the outcome of long-term potentiation (LTP)?
What is the outcome of long-term potentiation (LTP)?
In which scenario would a decrease in neurotransmitter release likely occur?
In which scenario would a decrease in neurotransmitter release likely occur?
Which type of memory lasts the longest?
Which type of memory lasts the longest?
What role does the process of consolidation play in memory?
What role does the process of consolidation play in memory?
What characterizes the divergent pathway in neuronal processing?
What characterizes the divergent pathway in neuronal processing?
What structural change can occur during memory formation?
What structural change can occur during memory formation?
What initiates the action potential in a neuron?
What initiates the action potential in a neuron?
What is primarily affected in multiple sclerosis?
What is primarily affected in multiple sclerosis?
Which change occurs at an excitatory synapse?
Which change occurs at an excitatory synapse?
What happens to Na+ ions during saltatory conduction?
What happens to Na+ ions during saltatory conduction?
What type of membrane potential change occurs during an inhibitory synapse?
What type of membrane potential change occurs during an inhibitory synapse?
How does cocaine affect neurotransmitter transmission?
How does cocaine affect neurotransmitter transmission?
What is the primary function of the axon in a neuron?
What is the primary function of the axon in a neuron?
Which type of ion channels are always open and allow potassium ions to move freely across the membrane?
Which type of ion channels are always open and allow potassium ions to move freely across the membrane?
What is the primary event that triggers the generation of an action potential in a neuron?
What is the primary event that triggers the generation of an action potential in a neuron?
Which mechanism terminates synaptic transmission?
Which mechanism terminates synaptic transmission?
What is a key characteristic of graded potentials?
What is a key characteristic of graded potentials?
Which ion primarily causes the depolarization phase of an action potential?
Which ion primarily causes the depolarization phase of an action potential?
During which phase of an action potential does potassium ion efflux primarily occur?
During which phase of an action potential does potassium ion efflux primarily occur?
What distinct feature does a synapse have?
What distinct feature does a synapse have?
What is the state called when a neuron cannot generate another action potential immediately after one has occurred?
What is the state called when a neuron cannot generate another action potential immediately after one has occurred?
What characterizes a graded potential compared to an action potential?
What characterizes a graded potential compared to an action potential?
Which of the following neurotoxins blocks voltage-gated sodium channels?
Which of the following neurotoxins blocks voltage-gated sodium channels?
Which structure in the neuron contributes to the formation of synapses?
Which structure in the neuron contributes to the formation of synapses?
What is the primary role of myelin in neurons?
What is the primary role of myelin in neurons?
During the hyperpolarization phase of an action potential, which ion channel closes slowly?
During the hyperpolarization phase of an action potential, which ion channel closes slowly?
What effect does tetrodotoxin (TTX) have on neuronal function?
What effect does tetrodotoxin (TTX) have on neuronal function?
What change occurs in the membrane potential during depolarization?
What change occurs in the membrane potential during depolarization?
Which ion movement is responsible for the repolarization phase of the action potential?
Which ion movement is responsible for the repolarization phase of the action potential?
In which type of conduction does the action potential jump from node to node?
In which type of conduction does the action potential jump from node to node?
Flashcards
Central Nervous System (CNS)
Central Nervous System (CNS)
The brain and spinal cord; the control center of the body.
Peripheral Nervous System (PNS)
Peripheral Nervous System (PNS)
Nerves outside the CNS; connects the CNS to the rest of the body.
Astrocytes
Astrocytes
Star-shaped glial cells that support neurons structurally and metabolically. Form the Blood-Brain Barrier.
Blood-Brain Barrier (BBB)
Blood-Brain Barrier (BBB)
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Grey matter
Grey matter
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White matter
White matter
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Cerebrospinal Fluid (CSF)
Cerebrospinal Fluid (CSF)
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Meninges
Meninges
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Cerebral Cortex
Cerebral Cortex
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Cerebellum
Cerebellum
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Hypothalamus
Hypothalamus
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Neuron
Neuron
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Oligodendrocytes
Oligodendrocytes
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Broca's area
Broca's area
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Wernicke's area
Wernicke's area
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Spinal Cord Function
Spinal Cord Function
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Spinal Nerve Types
Spinal Nerve Types
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Ascending/Descending Tracts
Ascending/Descending Tracts
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Afferent vs Efferent Fibers
Afferent vs Efferent Fibers
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Nerve vs Neuron
Nerve vs Neuron
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Membrane Potential
Membrane Potential
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Resting Membrane Potential
Resting Membrane Potential
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What maintains the resting membrane potential?
What maintains the resting membrane potential?
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Depolarization
Depolarization
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Hyperpolarization
Hyperpolarization
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Graded Potential
Graded Potential
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Action Potential
Action Potential
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Threshold Potential
Threshold Potential
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How is an action potential generated?
How is an action potential generated?
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Repolarization
Repolarization
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Refractory Period
Refractory Period
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Contiguous Conduction
Contiguous Conduction
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Saltatory Conduction
Saltatory Conduction
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Tetrodotoxin (TTX)
Tetrodotoxin (TTX)
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How does myelination increase conduction speed?
How does myelination increase conduction speed?
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Nodes of Ranvier
Nodes of Ranvier
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Action Potential (AP)
Action Potential (AP)
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Graded potential (GP)
Graded potential (GP)
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Multiple sclerosis (MS)
Multiple sclerosis (MS)
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Axon
Axon
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Dendrite
Dendrite
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Synapse
Synapse
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Neurotransmitter
Neurotransmitter
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Synaptic transmission
Synaptic transmission
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Temporal Summation
Temporal Summation
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Spatial Summation
Spatial Summation
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IPSP - EPSP Cancellation
IPSP - EPSP Cancellation
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Divergent Pathway
Divergent Pathway
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Convergent Pathway
Convergent Pathway
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Frequency of Action Potential
Frequency of Action Potential
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Consolidation
Consolidation
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Long-Term Potentiation (LTP)
Long-Term Potentiation (LTP)
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Study Notes
Human Physiology BIOL3205 - Nervous System I - Structure
- Â The nervous system comprises three components: central, peripheral, and enteric.
- Â The central nervous system (CNS) consists of the brain and spinal cord.
- Â The peripheral nervous system (PNS) encompasses both afferent and efferent divisions.
- Â The somatic nervous system controls voluntary actions.
- Â The autonomic nervous system regulates involuntary actions, which are further divided into sympathetic and parasympathetic systems.
- Â The enteric nervous system manages digestion and is part of the autonomic system.
Nervous System Structure I - Cells
- Glial cells account for 90% of brain volume, supporting neurons structurally and metabolically.
- Astrocytes, star-shaped cells, maintain the spatial relationships within the CNS.
- Astrocytes create the blood-brain barrier (BBB), transferring nutrients from the blood to neurons and clearing toxic byproducts.
- Oligodendrocytes produce the myelin sheath, crucial for nerve impulse transmission.
- Microglia are inactive cells that remove foreign invaders or tissue debris, playing roles in neurodegenerative diseases.
- Ependymal cells form the lining of the ventricles and create cerebrospinal fluid (CSF).
Nervous System Structure I - Gray and White Matter
- Grey matter contains densely packed cell bodies (non-myelinated).
- White matter comprises myelinated axons.
- The brain's superior region contains grey matter, while the interior has white matter.
- The spinal cord has superior white matter and interior grey matter.
- Impulse transmission speed varies based on myelination.
Nervous System Structure I - Protection
- The CNS is protected by the cranium (skull) and vertebral column.
- Protective membranes called meninges (dura mater, arachnoid mater, pia mater) surround the brain and spinal cord.
- Cerebrospinal fluid (CSF) cushions the CNS and maintains a consistent environment.
- The blood-brain barrier (BBB) selectively regulates the substances entering the brain.
Nervous System Structure I - Brain
- The brain begins as a hollow tube during embryonic development, retaining this structure throughout formation.
- The brain contains four interconnected ventricles (two lateral ventricles, third ventricle, and fourth ventricle).
- The fourth ventricle extends into the spinal cord as a central canal, containing cerebrospinal fluid.
Nervous System Structure I - Cerebral Spinal Fluid (CSF)
- CSF volume is approximately 150 ml.
- CSF has a similar density to the brain, enabling it to float or suspend brain tissues.
- CSF is manufactured by choroid plexuses, specialized structures in the brain's ventricles.
- CSF flows through the ventricles and into the spinal cord's central canal.
- CSF is reabsorbed into the subarachnoid space.
- CSF safeguards the brain from impact damage.
Nervous System Structure I - Brain Injury
- Â Coup injuries occur when the brain strikes the skull on the same side of impact.
- Â Contrecoup injuries occur when the brain strikes the opposite side of the skull from impact.
- Â Shaken baby syndrome can cause neurological damage.
Nervous System Structure I - Cerebral Spinal Fluid Composition
- Cerebrospinal fluid (CSF) contains substances like Na+, K+, Ca2+, Cl-, HCO3−, PCO2, differing from blood composition.
- Â Lower K+ levels exist in CSF in comparison to blood.
- CSF contains smaller amounts of protein.
- CSF facilitates ion transport, crucial for neural impulses.
Nervous System Structure I - Brain Organization
- Brainstem is responsible for vegetative functions.
- Cerebellum manages subconscious coordination of motor activity.
- Forebrain components include the diencephalon (hypothalamus for homeostasis, thalamus for sensory processing) and the cerebrum (basal nuclei for coordinating movement and cerebral cortex for decision-making).
Nervous System Structure I - Functional Areas of the Cortex
- Divided into distinctive areas like frontal lobe, parietal lobe, occipital lobe, and temporal lobe.
- Subdivided further by specific functions, such as primary motor cortex, somatosensory cortex.
Nervous System Structure I - Homunculus
- Depicts the location and relative amount of cortical area dedicated to sensory input and motor output.
- Distribution within the brain is uneven.
- Sensitivity and movement precision are unevenly distributed.
- The homunculus varies among individuals, adaptable (plasticity).
Nervous System Structure I - Neuron vs. Nerve
- Nerves are bundles of peripheral neuronal axons encased by connective tissue.
- Nerves have a similar pathway.
- Nerves do not contain complete neurons.
- Fibers within a nerve don't influence each other.
- Nerves in the CNS are called tracts, lacking the same structure as peripheral nerves.
Nervous System Structure I - Renewal of Neurons
- Most neurons are generated during embryonic development and remain throughout life.
- Ependymal cells are neural stem cells.
- New neurons are produced in the hippocampus.
- Neurogenesis occurs in the hippocampus, new neurons actively formed, die and are replaced, part of the neurogenesis process.
Nervous System Structure I - Lecture Summary
- The aim of the lecture series is to elucidate the structure and functions of the central and peripheral nervous systems, encompassing the cellular mechanisms, protective mechanisms (like the blood-brain barrier), and functions of brain regions. This includes neuron vs. nerve, regeneration, and methods for identifying active brain regions in terms of correlation and fMRI or MRI.
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