Neuroscience Chapter on Muscle Force

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Questions and Answers

What does motor unit recruitment primarily depend on?

  • The intensity of a task (correct)
  • The speed of contraction
  • The type of exercise performed
  • The size of the muscle fibers

Which statement best describes the size principle?

  • Motor units are recruited from smallest to largest during tasks. (correct)
  • Larger motor units are always recruited first.
  • Smaller motor units are recruited at higher exercise intensities.
  • Motor units fire randomly regardless of size.

What characterizes the all or none principle in muscle contraction?

  • All motor units pause before contracting.
  • Once a motor unit fires, all its muscle fibers contract simultaneously. (correct)
  • The contraction strength can be varied across motor units.
  • Some muscle fibers contract while others do not.

Which of the following is NOT a mechanism of fatigue?

<p>Reflex fatigue (A)</p> Signup and view all the answers

What determines the gradation of force during muscle actions?

<p>Motor unit recruitment and rate code (D)</p> Signup and view all the answers

What effect does an increase in the rate of motor unit firing have on muscle force generation?

<p>It increases muscle force generation. (A)</p> Signup and view all the answers

What defines a muscle twitch?

<p>A single muscle contraction in response to one nerve impulse. (C)</p> Signup and view all the answers

What is the term for the phenomenon when a second action potential increases tension before the muscle has relaxed?

<p>Twitch summation. (B)</p> Signup and view all the answers

What does 'neural load' refer to during physical activity?

<p>The amount of energy expenditure required by the central nervous system. (B)</p> Signup and view all the answers

What type of fatigue occurs within the central nervous system?

<p>Central fatigue. (B)</p> Signup and view all the answers

What effect does prolonged exercise have on the central nervous system's (CNS) workload?

<p>The CNS must increase its effort to preserve motor output. (A)</p> Signup and view all the answers

Which statement best describes a low stimulus to fatigue ratio in training?

<p>It implies insufficient training stimulus relative to high fatigue. (D)</p> Signup and view all the answers

What role do muscle spindles play in the stretch reflex?

<p>They cause the stretched muscle to contract and the opposing muscle to relax. (A)</p> Signup and view all the answers

What type of receptor do muscles and tendons contain that generate reflex actions?

<p>Proprioceptors (B)</p> Signup and view all the answers

What is the process of reciprocal inhibition during muscle contractions?

<p>It allows the agonist muscle to relax while the antagonist contracts. (A)</p> Signup and view all the answers

What is the primary consequence of impaired calcium handling during peripheral fatigue?

<p>Reduced calcium release from the sarcoplasmic reticulum (D)</p> Signup and view all the answers

Which neurotransmitter's accumulation is most likely associated with feelings of sleepiness and lethargy during central fatigue?

<p>Serotonin (B)</p> Signup and view all the answers

What effect does afferent inhibitory feedback have on motor neuron excitability during fatigue?

<p>Decreases lower motor neuron excitability (A)</p> Signup and view all the answers

What primarily leads to the accumulation of hydrogen ions during prolonged exercise?

<p>Inability to remove lactate efficiently (B)</p> Signup and view all the answers

Which factor is NOT a contributing element to neural load during high-intensity exercise?

<p>Nutrition level (D)</p> Signup and view all the answers

What is a possible sign of central fatigue in an athlete?

<p>Decreased muscular strength (A)</p> Signup and view all the answers

How does training affect neural load in athletes?

<p>Decreases neural load as movements become more coordinated (C)</p> Signup and view all the answers

What role does the postsynaptic nicotinic receptor play during peripheral fatigue?

<p>Decreases sensitivity, impairing excitation (C)</p> Signup and view all the answers

What is the primary function of muscle spindles?

<p>Detect changes in muscle length (A)</p> Signup and view all the answers

Which statement about extrafusal and intrafusal fibers is correct?

<p>Intrafusal fibers are aligned parallel to extrafusal fibers. (B)</p> Signup and view all the answers

What happens during the coactivation of alpha and gamma motor neurons?

<p>Muscle spindles maintain their sensitivity. (B)</p> Signup and view all the answers

Golgi tendon organs (GTOs) primarily function to:

<p>Trigger muscle relaxation in response to excessive tension. (D)</p> Signup and view all the answers

In which scenario will Golgi tendon organs inhibit the motor neuron?

<p>When muscle tension is too high. (D)</p> Signup and view all the answers

Which statement about alpha motor neurons is true?

<p>They innervate force-generating extrafusal fibers. (A)</p> Signup and view all the answers

What occurs if the stretch is held for approximately 30-60 seconds?

<p>Autogenic inhibition will trigger muscle relaxation. (B)</p> Signup and view all the answers

Which type of muscle would likely contain more muscle spindles per gram?

<p>Muscles involved in fine motor skills. (D)</p> Signup and view all the answers

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Study Notes

Neural Drive

  • Neural drive is the magnitude of motor output that dictates muscle force and movement.

Gradation of Force

  • How muscles produce different amounts of force for various tasks.
  • Dictated by:
    • Motor unit recruitment
    • Rate code

Motor Unit Recruitment

  • The number of motor units activated during muscle action.
  • Higher intensity tasks recruit more motor units.
  • Dependent on task intensity, force, and speed.

Size Principle

  • Motor units are recruited from smallest to largest.
  • Smaller motor neurons (type I fibers) have lower thresholds and are recruited first.
  • Larger motor neurons (type IIa and IIx fibers) have higher thresholds and require greater neural drive.

The All or None Principle

  • When a motor unit fires, all muscle fibers within that unit contract simultaneously.
  • Either a stimulus elicits an action potential or it does not.

Rate Code

  • The frequency of motor unit firing.
  • Higher frequency leads to greater force generation.
  • Muscle twitch is the smallest unit of muscle contraction.
  • Twitch summation occurs when motor units fire before relaxation, leading to greater tension.
  • Tetanus is a sustained muscle contraction from maximal motor unit firing.

Neural Load and Fatigue

  • Neural load is the stress on the nervous system during activity.
  • It relates to the amount of neural activity and energy required for muscle coordination.
  • Fatigue is a reduction in force production due to:
    • Central fatigue (processes within the CNS reducing neural drive)
    • Peripheral fatigue (processes at or distal to the neuromuscular junction)

Mechanisms of Fatigue

  • Central fatigue mechanisms:
    • Decreased motor cortex activity
    • Neurotransmitter imbalance
  • Peripheral fatigue mechanisms:
    • Substrate depletion (muscle glycogen, phosphocreatine)
    • Metabolite accumulation (lactate, H+)
    • Calcium handling (reduced release and uptake)
    • Impaired excitation (receptor sensitivity, ion disruption)
  • Motor unit recruitment, afferent inhibitory feedback, and duration/intensity of feedback all contribute to muscle fatigue.

Stimulus to Fatigue Ratio

  • A high stimulus to fatigue ratio indicates effective training programs that promote adaptation.
  • Low stimulus to fatigue ratios suggest inadequate training or disproportionate fatigue.

Reflexes

  • Involuntary, near-instantaneous actions in response to stimuli.
  • Occur via a reflex arc (sensory neuron, interneuron, motor neuron).

Proprioceptors

  • Specialized receptors within muscles and tendons that detect movement and position:
    • Muscle spindles
    • Golgi tendon organs

Muscle Spindles

  • Detect muscle stretch, specifically rate of lengthening.
  • Cause the stretched muscle to contract and the opposing muscle to relax.
  • Initiate the stretch reflex and reciprocal inhibition.

Stretch Reflex

  • Regulates muscle length by increasing contractility in response to stretching.
  • Example: knee jerk reflex.

Reciprocal Inhibition

  • Relaxation of antagonist muscles to accommodate agonist muscle contraction.

Muscle Spindle Structure

  • Intrafusal fibers: within the spindle, they do not generate force
  • Extrafusal fibers: outside the spindle, they generate force
  • More muscle spindles per gram of muscle are present in muscles involved in fine motor skills.

Alpha and Gamma Motor Neurons

  • Alpha motor neurons innervate extrafusal fibers.
  • Gamma motor neurons innervate intrafusal fibers and control their length.

Alpha-Gamma Coactivation

  • Simultaneous activation of alpha and gamma motor neurons maintains sensitivity during contraction.

Golgi Tendon Organs

  • Located at the myotendinous junction.
  • Detect muscle tension/force.
  • Trigger a relaxation response when tension is too high.

Autogenic Inhibition

  • A protective mechanism that prevents excess force generation.
  • Inhibits the motor neuron when excessive tension is detected.
  • Can occur during prolonged stretching, leading to muscle relaxation.

Length-Tension Relationship

  • The amount of force a muscle can produce varies with its length.
  • Optimal length allows for maximum cross-bridge formation and force generation.

Force-Velocity Relationship

  • As muscle contraction velocity increases, force production decreases.
  • A slower contraction allows for greater force generation.

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