Neuroscience and Neurology Quiz

Neuroscience and Neurology Quiz

Created by
@AppealingWoodland

Questions and Answers

Which subcortical nuclei includes the substantia nigra and supplies inhibitory signal to skeletal muscle?

Basal ganglia

Which lobe of the cerebrum is responsible for sensory functions?

Parietal lobe

Which part of the brain is associated with motor, behavior, emotions, and higher intellectual functions?

Frontal lobe

Which part of the brain is responsible for hearing and smelling?

<p>Temporal lobe</p> Signup and view all the answers

Which part of the brain includes the cerebrum, cerebellum, and brainstem?

<p>Cerebrum</p> Signup and view all the answers

Which cells are responsible for myelinating nerve fibers in the central nervous system?

<p>Oligodendroglia</p> Signup and view all the answers

What is the primary function of the meninges surrounding the brain?

<p>Protection and support</p> Signup and view all the answers

Which condition can lead to symptoms such as headache, vomiting, and potential brain herniation?

<p>Increased intracranial pressure</p> Signup and view all the answers

What is the role of cerebrospinal fluid in the central nervous system?

<p>Serving as a cushion and for material exchange</p> Signup and view all the answers

Which part of the central nervous system is responsible for sensory integration?

<p>Thalamus</p> Signup and view all the answers

Which neurological disorder is caused by sphingomyelinase deficiency leading to sphingomyelin accumulation in neurons?

<p>Niemann-Pick disease</p> Signup and view all the answers

Which vitamin deficiency can cause CNS lesions?

<p>Vitamin B12</p> Signup and view all the answers

What is the most common cause of dementia in the elderly?

<p>Alzheimer’s disease</p> Signup and view all the answers

Which neurodegenerative disease is characterized by decreased dopaminergic neurons in the substantia nigra and TRAP symptoms?

<p>Parkinson’s disease</p> Signup and view all the answers

What are gliomas?

<p>Tumors arising from glial cells</p> Signup and view all the answers

Which of the following is a cause of ischemic cerebrovascular disease?

<p>Thromboembolic occlusion of cerebral arteries</p> Signup and view all the answers

What is the primary characteristic of dysraphic developmental disorders?

<p>Incomplete closure of the neural tube</p> Signup and view all the answers

Which condition can result from global ischemia?

<p>Multiinfarct dementia</p> Signup and view all the answers

What is a characteristic feature of hemorrhagic stroke?

<p>Rupture of blood vessels</p> Signup and view all the answers

What can cause increased intracranial pressure?

<p>Trauma</p> Signup and view all the answers

Which of the following is a characteristic of multiple sclerosis?

<p>It involves white matter demyelination</p> Signup and view all the answers

What is the primary cause of CNS trauma in the cervical spinal cord?

<p>Ligament rupture</p> Signup and view all the answers

How can CNS infections be acquired?

<p>Through vascular spread, direct extension, or ascending neural route</p> Signup and view all the answers

What is the primary impact of HIV on the CNS?

<p>Leads to AIDS-related encephalopathy</p> Signup and view all the answers

Which disease primarily affects infants under 6 months of age due to a specific enzyme deficiency?

<p>$Tay-Sachs$ disease</p> Signup and view all the answers

Is epidural hematoma classified as arterial hemorrhage?

<p>True</p> Signup and view all the answers

Subdural hematoma is caused by arterial hemorrhage.

<p>False</p> Signup and view all the answers

Subarachnoid hemorrhage is usually due to trauma or rupture of aneurysms.

<p>True</p> Signup and view all the answers

Intracerebral hemorrhage can be caused by stroke or tumor.

<p>True</p> Signup and view all the answers

Ischemic stroke accounts for 85% of all strokes.

<p>True</p> Signup and view all the answers

The acronym F.A.S.T. stands for Face, Arms, Speech, and Time.

<p>False</p> Signup and view all the answers

Ischemic cerebrovascular disease is categorized as hemorrhagic in 85% of cases.

<p>False</p> Signup and view all the answers

Cerebrovascular disease is the primary cause of CNS trauma.

<p>False</p> Signup and view all the answers

Cerebrovascular disease is also known as a 'brain attack.'

<p>True</p> Signup and view all the answers

Hemorrhagic stroke is caused by arterial hemorrhage.

<p>True</p> Signup and view all the answers

Sudden slurred speech is a sign of ischemic stroke

<p>True</p> Signup and view all the answers

Global ischemia can result in multiple small foci of ischemic necrosis

<p>True</p> Signup and view all the answers

Hypovolemic shock can lead to multiple small foci of ischemic necrosis in the brain

<p>True</p> Signup and view all the answers

Focal ischemia is always of thromboembolic origin

<p>False</p> Signup and view all the answers

Hemorrhagic stroke results from blood vessel rupture without occlusion

<p>True</p> Signup and view all the answers

Chronic severe systemic hypertension is a common cause of hemorrhagic stroke

<p>True</p> Signup and view all the answers

Cerebral amyloid angiopathy can cause hemorrhagic stroke

<p>True</p> Signup and view all the answers

Intracranial aneurysm can cause hemorrhagic stroke

<p>True</p> Signup and view all the answers

Ischemic necrosis may result in profound neurologic deficits depending on the site of occlusion

<p>True</p> Signup and view all the answers

Physical and occupational therapy are important for long-term rehabilitation after ischemic stroke

<p>True</p> Signup and view all the answers

Ischemic stroke is characterized by rupture of blood vessels without occlusion.

<p>False</p> Signup and view all the answers

Global ischemia can result in multiple small foci of ischemic necrosis.

<p>True</p> Signup and view all the answers

Hypertension is the most common cause of hemorrhagic stroke.

<p>True</p> Signup and view all the answers

Focal ischemia is always of thromboembolic origin.

<p>False</p> Signup and view all the answers

Intracranial aneurysm can cause hemorrhagic stroke.

<p>True</p> Signup and view all the answers

Cerebral amyloid angiopathy is a potential cause of hemorrhagic stroke.

<p>True</p> Signup and view all the answers

Hypovolemic shock can lead to multiple small foci of ischemic necrosis in the brain.

<p>False</p> Signup and view all the answers

Physical and occupational therapy are important for long-term rehabilitation after ischemic stroke.

<p>True</p> Signup and view all the answers

Cerebral arteriovenous malformation is a cause of hemorrhagic stroke.

<p>True</p> Signup and view all the answers

Subarachnoid hemorrhage is usually due to trauma or rupture of aneurysms.

<p>False</p> Signup and view all the answers

Is intracranial hemorrhage always immediately apparent after trauma?

<p>False</p> Signup and view all the answers

Subdural hematoma is caused by venous hemorrhage.

<p>True</p> Signup and view all the answers

Intracerebral hemorrhage can be caused by stroke or tumor.

<p>True</p> Signup and view all the answers

Is cerebral vascular disease primarily caused by trauma to the CNS?

<p>False</p> Signup and view all the answers

Is F.A.S.T. an acronym used to identify symptoms of stroke?

<p>True</p> Signup and view all the answers

Is ischemic stroke categorized as 85% of all strokes?

<p>True</p> Signup and view all the answers

Is subarachnoid hemorrhage usually due to rupture of aneurysms?

<p>True</p> Signup and view all the answers

Is intracerebral hemorrhage caused by hemorrhage into substance of the brain from intracerebral vessels?

<p>True</p> Signup and view all the answers

Is hemorrhagic stroke primarily caused by arterial hemorrhage?

<p>True</p> Signup and view all the answers

Is intracranial hemorrhage classified into 4 groups based on location?

<p>True</p> Signup and view all the answers

Study Notes

Neurological Disorders Overview

  • Niemann-Pick disease is caused by sphingomyelinase deficiency leading to sphingomyelin accumulation in neurons, resulting in toxicity.
  • Deficiencies of certain vitamins cause CNS lesions, including thiamine (vitamin B1), vitamin B12, and nicotinic acid (vitamin B3).
  • Alcohol has profound effects on the brain, causing nutritional and metabolic disturbances, repeated head trauma, and direct atrophy.
  • Neurodegenerative diseases, such as Alzheimer’s, Huntington’s, Parkinson’s, and ALS, affect specific parts of the brain and have unknown etiologies.
  • Alzheimer’s disease is the most common cause of dementia in the elderly, leading to progressive impairment of cognitive and motor functions.
  • Parkinson’s disease is a subcortical neurodegenerative disease characterized by decreased dopaminergic neurons in the substantia nigra and TRAP symptoms.
  • Huntington disease is an autosomal dominant neurodegenerative disease caused by a mutation in the huntingtin (HTT) gene, leading to involuntary movements and progressive dementia.
  • ALS, also known as Lou Gehrig’s disease, is a progressive and fatal motor neuron disease characterized by motor weakness and muscle wasting, leading to paralysis of respiratory muscles.
  • The objectives of the text include describing the structure and function of the central nervous system, causes and symptoms of increased intracranial pressure, and classification of CNS trauma.
  • Approximately 50% of CNS neoplasms are primary, with gliomas and meningiomas being common types.
  • Gliomas are tumors arising from glial cells and can have different prognoses, with glioblastoma being highly aggressive and having a poor prognosis.
  • Meningiomas are neoplasms arising from meninges, usually benign but potentially fatal if located in vital areas.

Central Nervous System (CNS) Trauma, Infections, and Diseases Overview

  • The cervical spinal cord is the most vulnerable to injury due to its high mobility.
  • CNS trauma can result in ligament rupture, spinal nerve compression, and spinal cord transection.
  • CNS infections can be acquired through vascular spread, direct extension, or ascending neural route.
  • Meningitis can be acute pyogenic (bacterial), aseptic (viral), or chronic (tuberculosis, fungal infections).
  • Viruses such as HIV can cause encephalitis and impact the CNS, leading to AIDS-related encephalopathy.
  • Prions are infectious protein particles that selectively infect the nervous system, causing diseases like Creutzfeldt-Jakob disease.
  • Multiple sclerosis is an autoimmune demyelinating disease with a chronic relapsing and remitting course.
  • Its pathology involves white matter demyelination, leading to sensory and motor symptoms.
  • CNS metabolic diseases include inborn errors of metabolism like Tay-Sachs and Niemann-Pick disease.
  • Tay-Sachs disease results from Hexosaminidase A deficiency and primarily affects infants under 6 months of age.
  • CNS trauma, infections, and diseases are important to understand for their impact on the structure and function of the central nervous system.
  • Understanding the causes, symptoms, and clinical presentations of these conditions is essential for effective diagnosis and treatment.

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