Neuroscience: Action Potentials and Ion Channels

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Questions and Answers

What occurs during the hyperpolarization phase of a neuron?

  • Membrane potential rises above resting state
  • Membrane potential drops below resting state (correct)
  • Membrane potential stabilizes at resting state
  • Sodium channels open completely

What characterizes the absolute refractory period?

  • Sodium channels are inactivated (correct)
  • Partial recovery of membrane potential occurs
  • New action potentials are possible with a weaker stimulus
  • Action potential can be generated with any stimulus

What is the role of the myelin sheath in neuron function?

  • Prevents the formation of nodes of Ranvier
  • Inhibits signal transmission speed
  • Speeds up signal transmission (correct)
  • Facilitates backward signal transmission

During which phase is a stronger stimulus required to initiate an action potential?

<p>Relative refractory period (D)</p>
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What are the gaps created by the myelin sheath called?

<p>Nodes of Ranvier (A)</p>
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What is the typical resting membrane potential of neurons?

<p>-70 mV (C)</p>
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Which ion is found in higher concentration outside the neuron at resting membrane potential?

<p>Sodium (Na+) (D)</p>
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What triggers the all-or-nothing response in action potentials?

<p>Reaching the threshold of -55 mV (B)</p>
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During the depolarization phase of an action potential, which of the following occurs?

<p>Sodium ions rush into the cell (A)</p>
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What role do sodium-potassium pumps play in neurons?

<p>Maintain resting membrane potential (D)</p>
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What occurs during the repolarization phase of an action potential?

<p>Potassium ions flow out of the cell (A)</p>
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Which type of ion channel is always open and allows for passive transport of ions?

<p>Leak channels (B)</p>
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What primarily initiates the action potential in a neuron?

<p>The rapid influx of sodium ions (A)</p>
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Flashcards

Hyperpolarization

A brief period after an action potential where the membrane potential dips below the resting state.

Absolute Refractory Period

The period after an action potential where a new one cannot be triggered.

Relative Refractory Period

The period after an action potential where a stronger stimulus is needed to trigger a new one.

Myelin Sheath

A fatty insulating material around axons that speeds up signal conduction.

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Nodes of Ranvier

Gaps in the myelin sheath that allow for faster signal transmission.

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Neurons

Specialized cells that transmit information throughout the body, acting as the body's electrical communication system.

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Resting Membrane Potential

The default state of neurons when not transmitting signals. It is characterized by a negative charge inside the cell, typically around -70 millivolts.

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Ion Channels

Proteins embedded in the cell membrane that control the movement of ions across the membrane. They are responsible for generating action potentials.

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Action Potential Initiation

A change in the membrane potential that occurs when a neuron receives a stimulus that is strong enough to reach the threshold.

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Depolarization Phase

The phase of an action potential where the membrane potential rapidly becomes more positive due to the influx of sodium ions into the cell.

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Repolarization Phase

The phase of an action potential where the membrane potential returns to its resting state as potassium ions flow out of the cell, restoring the negative charge inside.

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Refractory Period

A period after an action potential where the neuron is less responsive to stimulation. It acts as a safety mechanism to prevent continuous firing.

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Action Potential Propagation

The transmission of an action potential down the axon of a neuron. It is a rapid, all-or-nothing event.

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Study Notes

Action Potentials: Neural Signal Transmission

  • Neurons are specialized cells transmitting information throughout the body
  • Key components of a neuron include the cell body, dendrites, axon, and axon terminals
  • Neurons function as the body's electrical communication system
  • They are essential for thoughts, movements, sensations, and bodily functions

Resting Membrane Potential

  • The default state of neurons when not transmitting signals
  • Typically around -70 millivolts (mV)
  • Maintained by sodium-potassium pumps
  • More sodium (Na+) outside the cell
  • More potassium (K+) inside the cell
  • Creates an electrical gradient across the membrane

Ion Channels

  • Specialized proteins in cell membranes
  • Types include:
    • Voltage-gated channels: Open and close based on membrane potentials
    • Ligand-gated channels: Open and close based on specific chemicals (neurotransmitters)
    • Leak channels: Always open, allowing ions to move across the membrane via passive transport
  • Crucial for action potential generation, controlling ion movement

Action Potential Initiation

  • A stimulus causes sodium channels to open
  • Sodium ions rush into the cell
  • Membrane potential becomes more positive
  • Threshold potential reached at -55 mV
  • Triggers an all-or-nothing response

Depolarization Phase

  • Rapid influx of sodium ions
  • Membrane potential becomes positive, peaking at approximately +30 mV
  • Sodium channels begin to close
  • Potassium channels open

Repolarization Phase

  • Potassium ions flow out of the cell
  • Membrane potential returns towards the resting state
  • Sodium channels remain inactive
  • Active transport of ions begins

Hyperpolarization

  • Brief period where membrane potential drops below resting state
  • Also called the refractory period
  • Prevents backwards signal transmission
  • Ensures one-way signal propagation

Refractory Periods

  • Absolute refractory period: No new action potential possible; sodium channels inactive
  • Relative refractory period: Stronger stimulus needed for a new action potential; partial recovery phase

Myelin Sheath

  • Insulating material around axons
  • Produced by glial cells called Schwann cells
  • Speeds up signal transmission
  • Creates gaps called nodes of Ranvier
  • Enables saltatory conduction

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