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Questions and Answers
What determines if a channel is open or not?
What determines if a channel is open or not?
Channel activation or gating mechanisms
Describe the different states of a sodium channel during an action potential.
Describe the different states of a sodium channel during an action potential.
Resting/deactivated, Activated, Inactivated
What ion movement underlies the membrane depolarization during an action potential?
What ion movement underlies the membrane depolarization during an action potential?
Entry of Na+ ions
What process leads to the repolarization of the cell membrane after depolarization?
What process leads to the repolarization of the cell membrane after depolarization?
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What is the significance of Na+ channels in the initiation of an action potential?
What is the significance of Na+ channels in the initiation of an action potential?
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Explain the concept of equilibrium potential in relation to Na+ ions during an action potential.
Explain the concept of equilibrium potential in relation to Na+ ions during an action potential.
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What is the basis of nerve conduction?
What is the basis of nerve conduction?
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Explain the ionic basis of action potential with reference to the ECG.
Explain the ionic basis of action potential with reference to the ECG.
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What role do ion channels play in excitability?
What role do ion channels play in excitability?
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Outline what makes a membrane excitable.
Outline what makes a membrane excitable.
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Explain the basis of the membrane potential.
Explain the basis of the membrane potential.
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How do ion channels contribute to membrane excitability?
How do ion channels contribute to membrane excitability?
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What is the resting membrane potential primarily determined by?
What is the resting membrane potential primarily determined by?
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During which phase of the myocyte action potential does activation of voltage-gated Na+ channels occur?
During which phase of the myocyte action potential does activation of voltage-gated Na+ channels occur?
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What is the 'plateau' phase of the myocyte action potential characterized by?
What is the 'plateau' phase of the myocyte action potential characterized by?
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What is the primary cause of early repolarization during the myocyte action potential?
What is the primary cause of early repolarization during the myocyte action potential?
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How is repolarization phase achieved in the myocyte action potential?
How is repolarization phase achieved in the myocyte action potential?
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Why might injection of a bolus of KCl lead to heart failure?
Why might injection of a bolus of KCl lead to heart failure?
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