Neurophysiology and Brain Metabolism

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What percentage of total body oxygen consumption is the adult brain responsible for?

10%

20% (correct)

30%

40%

What is the normal cerebral blood flow (CBF) in mL/100 g/min?

50 (correct)

30

40

60

How long of global ischemia can potentially cause irreversible injury to the brain?

6-7 minutes

4-5 minutes (correct)

8-10 minutes

2-3 minutes

What does CPP stand for in the context of neurophysiology?

Cerebral Perfusion Pressure Signup and view all the answers

What is the difference between mean arterial pressure (MAP) and either intracranial pressure (ICP) or central venous pressure (CVP) called?

Cerebrovascular Resistance (CVR) Signup and view all the answers

How does the brain regulate blood flow in response to moderate changes in mean arterial pressure (MAP) or cerebral perfusion pressure (CPP)?

It increases blood flow to maintain a consistent CBF Signup and view all the answers

What is the approximate range for the lower limit of autoregulation (LLA) of cerebral blood flow (CBF)?

60 to 100 mmHg Signup and view all the answers

Which phase of autoregulation responds to changes in systolic systemic blood pressure?

Rapid phase (dynamic autoregulation) Signup and view all the answers

What happens to cerebral blood flow (CBF) above the upper limit of autoregulation?

Becomes pressure-dependent Signup and view all the answers

What are the two types of autoregulation identified in the text?

Dynamic autoregulation and static autoregulation Signup and view all the answers

What physiological parameter besides mean arterial pressure (MAP) plays an important role in regulating cerebral blood flow (CBF)?

Arterial oxygen tension (PaO2) Signup and view all the answers

What effect does hypercapnia (elevated PaCO2) have on cerebral blood flow (CBF)?

Increases CBF Signup and view all the answers

How is regional cerebral blood flow (CBF) governed?

By a combination of humoral and neurogenic factors Signup and view all the answers

What effect do potent volatile anesthetics have on cerebral blood flow (CBF)?

Increase CBF Signup and view all the answers

What effect does nitrous oxide have on cerebral blood flow (CBF)?

Increase CBF Signup and view all the answers

Neurophysiology and Brain Metabolism

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Questions and Answers

What percentage of total body oxygen consumption is the adult brain responsible for?

What is the normal cerebral blood flow (CBF) in mL/100 g/min?

How long of global ischemia can potentially cause irreversible injury to the brain?

What does CPP stand for in the context of neurophysiology?

What is the difference between mean arterial pressure (MAP) and either intracranial pressure (ICP) or central venous pressure (CVP) called?

How does the brain regulate blood flow in response to moderate changes in mean arterial pressure (MAP) or cerebral perfusion pressure (CPP)?

What is the approximate range for the lower limit of autoregulation (LLA) of cerebral blood flow (CBF)?

Which phase of autoregulation responds to changes in systolic systemic blood pressure?

What happens to cerebral blood flow (CBF) above the upper limit of autoregulation?

What are the two types of autoregulation identified in the text?

What physiological parameter besides mean arterial pressure (MAP) plays an important role in regulating cerebral blood flow (CBF)?

What effect does hypercapnia (elevated PaCO2) have on cerebral blood flow (CBF)?

How is regional cerebral blood flow (CBF) governed?

What effect do potent volatile anesthetics have on cerebral blood flow (CBF)?

What effect does nitrous oxide have on cerebral blood flow (CBF)?

What happens to spinal cord perfusion pressure (SCPP) when spinal subarachnoid space pressure (SSSP) increases?

Which of the following substances has a cerebral vasoconstrictive effect?

What effect do opioids have on cerebral blood flow (CBF)?

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