Neuropathophysiology Etiology Quiz
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Questions and Answers

What type of neuron is typically responsible for detecting sensory stimuli in the periphery?

  • Unipolar neurons
  • Multipolar neurons
  • Bipolar neurons (correct)
  • Anaxonic neurons
  • Which part of the brain receives sensory information from second-order neurons?

  • Hippocampus
  • Thalamus (correct)
  • Cerebellum
  • Amygdala
  • What is released by first-order neurons to generate an action potential in the dorsal root ganglia?

  • Endorphins
  • Nitric oxide
  • Inhibitory neurotransmitter
  • Excitatory neurotransmitter (correct)
  • What type of synapse do first-order neurons make in the dorsal root ganglia?

    <p>Axodendritic synapse</p> Signup and view all the answers

    Which bundle also sends sensory information to the thalamus besides the spinothalamic bundle?

    <p>Paleospinothalamic bundle</p> Signup and view all the answers

    What is the term for the progressive loss of neuron structure or function, exemplified by Alzheimer’s disease?

    <p>Neurodegenerative disorders</p> Signup and view all the answers

    Which anatomical component of a neuron is responsible for transmitting information from the cell body to the presynaptic terminals?

    <p>Axons</p> Signup and view all the answers

    What is the term used to describe the functional component that transmits signals via neurotransmitters to adjacent neurons?

    <p>Presynaptic Terminals</p> Signup and view all the answers

    Which factor leads to reduced blood flow and oxygen, often occurring together as seen in conditions like stroke?

    <p>Ischemia + Hypoxia</p> Signup and view all the answers

    What is the name of the anatomical component of a neuron where most metabolic activity occurs and action potentials are generated?

    <p>Cell body</p> Signup and view all the answers

    What is the term for the continuous supply of glucose required by neurons to function properly?

    <p>&quot;Neurons' energy source&quot;</p> Signup and view all the answers

    What is the role of the Na+/K+ ATPase?

    <p>Brings in 3 Na+ and exports 2 K+</p> Signup and view all the answers

    What initiates the action potential in neurons?

    <p>Activation of Voltage-Gated Sodium Channels</p> Signup and view all the answers

    What happens during hyperpolarization of a neuron?

    <p>K+ channels close slowly, allowing positive K+ out</p> Signup and view all the answers

    How does a neuron reach the threshold for an action potential?

    <p>Depolarization of the membrane to -55 mV</p> Signup and view all the answers

    What effect does the influx of sodium have on a neuron?

    <p>Cell becomes more positive</p> Signup and view all the answers

    What function do Ion Channels serve in a neuron's response to stimuli?

    <p>Cause influx of sodium into the cell</p> Signup and view all the answers

    What is one effect of repeated application of identical nociceptive stimuli?

    <p>Increased neuron response</p> Signup and view all the answers

    In the context provided, what can lead to the development of chronic pain?

    <p>Micro-trauma and acute pain over time</p> Signup and view all the answers

    What is the role of local cytokines in the activation of immune cells?

    <p>Drive activation and polarization of immune cells</p> Signup and view all the answers

    Which type of cells secrete cytokines in response to allergies?

    <p>TH2 Cells</p> Signup and view all the answers

    What happens when neurons are stimulated by cytokines like IL-4 and IL-5?

    <p>Neurons activate RTKs</p> Signup and view all the answers

    How does the feedforward inflammatory loop involving TH2 cells contribute to allergies?

    <p>Secreting cytokines that exacerbate allergic responses</p> Signup and view all the answers

    What is the primary function of Trigeminal Ganglia?

    <p>Innervating the face, mouth, and eyes</p> Signup and view all the answers

    Which ion channel is activated by capsaicin found in hot peppers?

    <p>TRPV1</p> Signup and view all the answers

    Which ion channel is known for being activated by cold temperatures?

    <p>TRPM8</p> Signup and view all the answers

    Which ion channel is associated with detecting mechanical pressure?

    <p>Piezo</p> Signup and view all the answers

    What type of molecules activate TRPA1 ion channels?

    <p>Electrophilic ligands</p> Signup and view all the answers

    Which ion channel releases pro-inflammatory neurotransmitters when activated?

    <p>TRPV1</p> Signup and view all the answers

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