Neuropathophysiology Etiology Quiz
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Questions and Answers

What type of neuron is typically responsible for detecting sensory stimuli in the periphery?

  • Unipolar neurons
  • Multipolar neurons
  • Bipolar neurons (correct)
  • Anaxonic neurons

Which part of the brain receives sensory information from second-order neurons?

  • Hippocampus
  • Thalamus (correct)
  • Cerebellum
  • Amygdala

What is released by first-order neurons to generate an action potential in the dorsal root ganglia?

  • Endorphins
  • Nitric oxide
  • Inhibitory neurotransmitter
  • Excitatory neurotransmitter (correct)

What type of synapse do first-order neurons make in the dorsal root ganglia?

<p>Axodendritic synapse (D)</p> Signup and view all the answers

Which bundle also sends sensory information to the thalamus besides the spinothalamic bundle?

<p>Paleospinothalamic bundle (A)</p> Signup and view all the answers

What is the term for the progressive loss of neuron structure or function, exemplified by Alzheimer’s disease?

<p>Neurodegenerative disorders (D)</p> Signup and view all the answers

Which anatomical component of a neuron is responsible for transmitting information from the cell body to the presynaptic terminals?

<p>Axons (D)</p> Signup and view all the answers

What is the term used to describe the functional component that transmits signals via neurotransmitters to adjacent neurons?

<p>Presynaptic Terminals (C)</p> Signup and view all the answers

Which factor leads to reduced blood flow and oxygen, often occurring together as seen in conditions like stroke?

<p>Ischemia + Hypoxia (C)</p> Signup and view all the answers

What is the name of the anatomical component of a neuron where most metabolic activity occurs and action potentials are generated?

<p>Cell body (A)</p> Signup and view all the answers

What is the term for the continuous supply of glucose required by neurons to function properly?

<p>&quot;Neurons' energy source&quot; (B)</p> Signup and view all the answers

What is the role of the Na+/K+ ATPase?

<p>Brings in 3 Na+ and exports 2 K+ (B)</p> Signup and view all the answers

What initiates the action potential in neurons?

<p>Activation of Voltage-Gated Sodium Channels (B)</p> Signup and view all the answers

What happens during hyperpolarization of a neuron?

<p>K+ channels close slowly, allowing positive K+ out (D)</p> Signup and view all the answers

How does a neuron reach the threshold for an action potential?

<p>Depolarization of the membrane to -55 mV (D)</p> Signup and view all the answers

What effect does the influx of sodium have on a neuron?

<p>Cell becomes more positive (A)</p> Signup and view all the answers

What function do Ion Channels serve in a neuron's response to stimuli?

<p>Cause influx of sodium into the cell (D)</p> Signup and view all the answers

What is one effect of repeated application of identical nociceptive stimuli?

<p>Increased neuron response (D)</p> Signup and view all the answers

In the context provided, what can lead to the development of chronic pain?

<p>Micro-trauma and acute pain over time (C)</p> Signup and view all the answers

What is the role of local cytokines in the activation of immune cells?

<p>Drive activation and polarization of immune cells (D)</p> Signup and view all the answers

Which type of cells secrete cytokines in response to allergies?

<p>TH2 Cells (C)</p> Signup and view all the answers

What happens when neurons are stimulated by cytokines like IL-4 and IL-5?

<p>Neurons activate RTKs (C)</p> Signup and view all the answers

How does the feedforward inflammatory loop involving TH2 cells contribute to allergies?

<p>Secreting cytokines that exacerbate allergic responses (B)</p> Signup and view all the answers

What is the primary function of Trigeminal Ganglia?

<p>Innervating the face, mouth, and eyes (A)</p> Signup and view all the answers

Which ion channel is activated by capsaicin found in hot peppers?

<p>TRPV1 (D)</p> Signup and view all the answers

Which ion channel is known for being activated by cold temperatures?

<p>TRPM8 (A)</p> Signup and view all the answers

Which ion channel is associated with detecting mechanical pressure?

<p>Piezo (A)</p> Signup and view all the answers

What type of molecules activate TRPA1 ion channels?

<p>Electrophilic ligands (D)</p> Signup and view all the answers

Which ion channel releases pro-inflammatory neurotransmitters when activated?

<p>TRPV1 (D)</p> Signup and view all the answers
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