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Lec 21/22 - MCQ - Neurons and Glia
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Lec 21/22 - MCQ - Neurons and Glia

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Questions and Answers

Which cells are necessary for synapse formation in the central nervous system?

  • Neurons
  • Schwann cells
  • Astrocytes (correct)
  • Hippocampal stem cells

    • What role do astrocytes play in synaptogenesis?

  • Regulate synapse number
  • Regulate synapse stability
  • Regulate synapse function
  • All of the above (correct)

    • Which cells are necessary for synapse maintenance?

  • Schwann cells
  • Hippocampal stem cells
  • Neurons
  • Astrocytes (correct)

    • What triggers synapse formation in the central nervous system?

    <p>Extracellular protein signals from astrocytes</p> Signup and view all the answers

    Do adult hippocampal stem cells display a similar dependence on astrocytes for synapse formation?

    <p>Yes</p> Signup and view all the answers

    Which cells trigger neuromuscular junction formation in the periphery?

    <p>Schwann cells</p> Signup and view all the answers

    What do glia in culture sense in response to synaptic activity?

    <p>Calcium transient currents</p> Signup and view all the answers

    What do glia release in response to neuronal activity?

    <p>Gliotransmitters</p> Signup and view all the answers

    What is the role of astrocytes and other macroglia in synaptogenesis?

    <p>All of the above</p> Signup and view all the answers

    What triggers synapse formation in the central nervous system?

    <p>Extracellular protein signals from astrocytes</p> Signup and view all the answers

    Which of the following is responsible for the movement of ions across the cell membrane?

    <p>Diffusion through ion channels</p> Signup and view all the answers

    Which ions have an unequal distribution across the cell membrane at rest?

    <p>Na+ and K+</p> Signup and view all the answers

    Which ion has greater permeability across the cell membrane at rest?

    <p>K+</p> Signup and view all the answers

    What is the range of the resting membrane potential in most cells?

    <p>-60 to -80 mV</p> Signup and view all the answers

    What is the role of the Na+/K+ electrogenic pump?

    <p>It pumps 3 K+ ions out and 2 Na+ ions in, making the inside of the cell negative relative to the outside.</p> Signup and view all the answers

    What is the voltage difference across a cell membrane called?

    <p>Resting membrane potential</p> Signup and view all the answers

    What is the main factor contributing to the resting membrane potential?

    <p>Unequal distribution of ions</p> Signup and view all the answers

    What is the main function of neurons?

    <p>Generating electrical current</p> Signup and view all the answers

    What is the primary mechanism by which ions move across the cell membrane?

    <p>Diffusion through ion channels</p> Signup and view all the answers

    What is the role of glia in neurophysiology?

    <p>Supporting and protecting neurons</p> Signup and view all the answers

    Which equation can be used to predict the equilibrium potential for potassium (EK+)?

    <p>Nernst equation</p> Signup and view all the answers

    What is the resting membrane potential generally between?

    <p>-60 to -80 mV</p> Signup and view all the answers

    What is the function of the Na+/K+ electrogenic pump?

    <p>To maintain a negative charge inside the cell</p> Signup and view all the answers

    Which type of ion channels are composed of protein subunits and respond to changes in voltage?

    <p>Voltage-gated channels</p> Signup and view all the answers

    What is the threshold for the activation of voltage-gated Na+ channels during an action potential?

    <p>+15 mV</p> Signup and view all the answers

    What is the function of the inactivation gate during an action potential?

    <p>To facilitate AP propagation in one direction only</p> Signup and view all the answers

    What is the distance between nodes of Ranvier in an unmyelinated axon?

    <p>1-3 mm</p> Signup and view all the answers

    Which type of glial cells are responsible for myelination in the central nervous system (CNS)?

    <p>Oligodendrocytes</p> Signup and view all the answers

    What is the role of astrocytes in the brain?

    <p>Control of extracellular environment around neurons</p> Signup and view all the answers

    What is the function of metabotropic receptors?

    <p>Slow activation and long duration of action</p> Signup and view all the answers

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