Neuron and Glial Cell Classification

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Questions and Answers

What is a distinctive feature of unipolar neurons?

  • They have one process that includes both the axon and dendrite. (correct)
  • They have two processes: an axon and a dendrite.
  • Their dendrite branches from the axon.
  • They have multiple dendrites and one axon.

Where are bipolar neurons mainly found?

  • In the peripheral nervous system ganglia.
  • In the retina of the eye and olfactory epithelium. (correct)
  • In the motor cortex of the brain.
  • In the spinal cord only.

What distinguishes multipolar neurons from unipolar and bipolar neurons?

  • They consist of multiple dendrites emerging from the cell body. (correct)
  • Multipolar neurons are exclusively sensory neurons.
  • They have only one process.
  • Multipolar neurons have no axon.

What type of neuron are motor neurons classified as?

<p>Multipolar neurons. (B)</p> Signup and view all the answers

What is the function of astrocytes in the CNS?

<p>They provide structural support to neurons. (B)</p> Signup and view all the answers

In unipolar neurons, where is the cell body located?

<p>On the side between the two ends. (D)</p> Signup and view all the answers

Which type of glial cell is known for its star-shaped appearance?

<p>Astrocytes. (B)</p> Signup and view all the answers

Which of the following statements is true regarding bipolar neurons?

<p>They consist of two processes that extend from opposite ends of the cell body. (D)</p> Signup and view all the answers

What is the main function associated with the primary visual cortex (Brodmann area 17)?

<p>Primary visual perception (A)</p> Signup and view all the answers

Where is the primary motor cortex located?

<p>Precentral gyrus of the frontal lobe (A)</p> Signup and view all the answers

Which area is associated with the production of language?

<p>Broca’s area (B)</p> Signup and view all the answers

Which of the following is a function of the temporal lobe?

<p>Creating long-term memories (B)</p> Signup and view all the answers

What type of information is processed by the postcentral gyrus?

<p>Somatosensory information (A)</p> Signup and view all the answers

What is the role of the premotor area?

<p>Storing motor memory algorithms (A)</p> Signup and view all the answers

Brodmann’s areas are classifications based on what?

<p>Microscopic structure of the cortex (C)</p> Signup and view all the answers

What distinguishes primary cortical areas from association areas?

<p>Primary areas process sensory information and commands, while association areas do not. (D)</p> Signup and view all the answers

Which of the following senses is NOT processed in the postcentral gyrus?

<p>Visual information (D)</p> Signup and view all the answers

What role does the prefrontal cortex serve?

<p>Cognitive functions and personality (C)</p> Signup and view all the answers

What is the primary function of Brodmann areas 41 and 42?

<p>Hearing and auditory sensation (D)</p> Signup and view all the answers

What is the role of the central sulcus in relation to the motor and sensory cortex?

<p>Divides the frontal lobe from the parietal lobe (B)</p> Signup and view all the answers

Which area is primarily responsible for proprioceptive feedback?

<p>Parietal lobe (postcentral gyrus) (B)</p> Signup and view all the answers

What is primarily assessed during the praxis subtest?

<p>Transformation of verbal commands into motor movements (D)</p> Signup and view all the answers

Which task requires a patient to identify objects solely through tactile exploration?

<p>Stereognosis (B)</p> Signup and view all the answers

Which of the following brain regions is primarily linked to judgment and abstract reasoning?

<p>Prefrontal cortex (A)</p> Signup and view all the answers

What does the inability to distinguish between common verbs and nouns suggest?

<p>Cortical language impairment (D)</p> Signup and view all the answers

What aspect of personality may be influenced by the prefrontal cortex?

<p>Emotional regulation (C)</p> Signup and view all the answers

What type of reasoning is assessed when interpreting proverbs during a mental status exam?

<p>Abstract reasoning (B)</p> Signup and view all the answers

Which neurological procedure was historically used to treat various disorders but often affected personality?

<p>Frontal lobotomy (B)</p> Signup and view all the answers

How does gnosis differ from praxis in sensory perception tests?

<p>Gnosis assesses object manipulation while praxis assesses verbal commands (A)</p> Signup and view all the answers

What type of feedback do patients utilize while performing praxis tasks?

<p>Both visual and proprioceptive feedback (A)</p> Signup and view all the answers

Which of the following best describes the role of the insula in relation to language?

<p>It is associated with V impairment (D)</p> Signup and view all the answers

What can be inferred about Phineas Gage's case regarding the prefrontal cortex?

<p>The injury led to noticeable changes in personality traits (B)</p> Signup and view all the answers

What is the significance of comparing pairs of words in the judgment and abstract reasoning subtest?

<p>It measures semantic knowledge (C)</p> Signup and view all the answers

Why is language function considered integral to praxis and gnosis?

<p>They require understanding of verbal commands and object identification (D)</p> Signup and view all the answers

Which part of the cerebral cortex is primarily responsible for processing sensory information?

<p>Primary cortical areas (B)</p> Signup and view all the answers

What type of memory is affected in a patient with anterograde amnesia?

<p>Episodic memory of new experiences (A)</p> Signup and view all the answers

Which region integrates sensory information between the somatosensory and visual cortices?

<p>Posterior parietal cortex (C)</p> Signup and view all the answers

Which cognitive ability is primarily assessed by asking a patient about the current date and their identity?

<p>Orientation (A)</p> Signup and view all the answers

What memory task assesses the ability to recall information after a short interval?

<p>Three-word recall test (B)</p> Signup and view all the answers

Where is long-term storage of episodic memory likely located within the brain?

<p>Hippocampus and medial temporal lobe (B)</p> Signup and view all the answers

Which cognitive function is tested by spelling common words backwards?

<p>Memory (B)</p> Signup and view all the answers

What kind of memory remains intact for patient HM after surgery?

<p>Short-term memory (B), Working memory (D)</p> Signup and view all the answers

What is the role of the primary cortical areas?

<p>Process modality-specific input (B)</p> Signup and view all the answers

The inability to form new memories after surgery in patient HM is an example of which type of amnesia?

<p>Anterograde amnesia (B)</p> Signup and view all the answers

Which lobe contains structures critical for working memory?

<p>Frontal lobe (C)</p> Signup and view all the answers

What type of processing areas are responsible for complex sensory integrations?

<p>Integration areas (B)</p> Signup and view all the answers

Which type of memory is most likely impacted by damage to the hippocampus?

<p>Episodic memory (A)</p> Signup and view all the answers

What type of memory enables the consolidation of short-term memories into long-term storage?

<p>Episodic memory (D)</p> Signup and view all the answers

What is the primary function of the basal nuclei?

<p>To influence the likelihood of movement (A)</p> Signup and view all the answers

Which of the following structures is NOT part of the basal nuclei?

<p>Cerebellum (B)</p> Signup and view all the answers

Which part of the basal nuclei is referred to as the striatum?

<p>Caudate and putamen (D)</p> Signup and view all the answers

What neurotransmitter is primarily associated with the direct pathway in the basal nuclei?

<p>Dopamine (D)</p> Signup and view all the answers

Which pathway is characterized by inhibiting the thalamus?

<p>Indirect pathway (D)</p> Signup and view all the answers

The globus pallidus has how many subdivisions?

<p>Two (C)</p> Signup and view all the answers

What is the effect of dopamine on the indirect pathway?

<p>Inhibits it (C)</p> Signup and view all the answers

Which structure serves as a relay point between the basal nuclei and the cortex?

<p>Thalamus (B)</p> Signup and view all the answers

During which state is the body less likely to initiate movement due to the activity of the substantia nigra pars compacta?

<p>Passive state (C)</p> Signup and view all the answers

What type of neurotransmitter is primarily released by the cortex as input to the basal nuclei?

<p>Glutamate (A)</p> Signup and view all the answers

Disinhibition of the thalamus in the direct pathway leads to what outcome?

<p>Increased likelihood of movement (B)</p> Signup and view all the answers

What structure fits just medial to the putamen in the basal nuclei?

<p>Globus pallidus (D)</p> Signup and view all the answers

What is the outcome of the indirect pathway on cortical excitation?

<p>It inhibits cortical excitation (B)</p> Signup and view all the answers

In terms of shape, how are the globus pallidus and putamen collectively described?

<p>Lenticular nuclei (A)</p> Signup and view all the answers

What is the primary function of myelin in relation to axons?

<p>To facilitate the transmission of electrical signals along the axon (C)</p> Signup and view all the answers

Which component of the brain is primarily responsible for higher neurological functions such as memory and emotion?

<p>Cerebrum (D)</p> Signup and view all the answers

What are gyri and sulci in the context of the cerebral cortex?

<p>The folded surface and the grooves between the folds (A)</p> Signup and view all the answers

How do Schwann cells differ from oligodendrocytes in their myelination of axons?

<p>Oligodendrocytes can myelinate multiple axon segments simultaneously (A)</p> Signup and view all the answers

What structure primarily connects the two hemispheres of the cerebrum?

<p>Corpus callosum (A)</p> Signup and view all the answers

What neurological phenomenon is often misinterpreted by the concept of right-brained and left-brained people?

<p>The independence of the cerebral hemispheres (A)</p> Signup and view all the answers

Why do the gyri and sulci of the cerebral cortex enhance brain functionality?

<p>They increase the surface area for more gray matter (A)</p> Signup and view all the answers

Which lobe of the brain is primarily responsible for visual processing?

<p>Occipital lobe (D)</p> Signup and view all the answers

What is the primary function attributed to damage in Broca’s and Wernicke’s areas?

<p>Language and speech (D)</p> Signup and view all the answers

Which cerebral structure is directly linked to changes in personality and mood when damaged?

<p>Prefrontal cortex (B)</p> Signup and view all the answers

What primarily governs homeostasis in the nervous system?

<p>Diencephalon (D)</p> Signup and view all the answers

In a person with a sectioned corpus callosum, which scenario is likely to occur when asked about contents in both pockets?

<p>They will only identify contents in the right pocket. (C)</p> Signup and view all the answers

What is the role of the basal nuclei within the cerebrum?

<p>Facilitating planning and movement (B)</p> Signup and view all the answers

What key function is associated with the medial temporal lobe structures, including the hippocampus?

<p>Long-term memory formation (B)</p> Signup and view all the answers

During axon development, how is the glial cell initially wrapped around the axon?

<p>Loosely or incompletely (D)</p> Signup and view all the answers

Which part of the central nervous system is a single structure?

<p>The spinal cord (D)</p> Signup and view all the answers

What is the impact of a bilateral temporal lobectomy based on the case of patient HM?

<p>Results in severe memory loss (B)</p> Signup and view all the answers

What is the primary neurotransmitter produced in the basal forebrain that modulates cortical activity?

<p>Acetylcholine (B)</p> Signup and view all the answers

What defines the boundaries between different lobes of the cerebral cortex?

<p>Locations of large gyri and sulci (B)</p> Signup and view all the answers

What is the primary function of astrocytes in the central nervous system?

<p>Supporting the neurons and maintaining chemical balance (B)</p> Signup and view all the answers

What condition is associated with a loss of neurons in the basal forebrain?

<p>Alzheimer’s disease (A)</p> Signup and view all the answers

How does myelin benefit unmyelinated axons compared to myelinated ones?

<p>Myelinated axons send signals faster (D)</p> Signup and view all the answers

What essential structure separates the two hemispheres of the cerebrum?

<p>Longitudinal fissure (A)</p> Signup and view all the answers

How do astrocytes help maintain the blood-brain barrier?

<p>By inducing tight junctions between blood vessel cells (B)</p> Signup and view all the answers

Which area of the brain is primarily responsible for motion control of limbs?

<p>Precentral gyrus (B)</p> Signup and view all the answers

Which concept is demonstrated by a patient being able to perform two tasks simultaneously after a corpus callosum section?

<p>Independence of hemispheres (A)</p> Signup and view all the answers

Which type of glial cell in the CNS is responsible for creating myelin sheaths?

<p>Oligodendrocytes (A)</p> Signup and view all the answers

What functions do multimodal integration areas of the cortex primarily involve?

<p>Sensory perception and language processing (C)</p> Signup and view all the answers

What distinguishes Schwann cells from oligodendrocytes?

<p>Schwann cells only wrap around one axon segment. (D)</p> Signup and view all the answers

What role do ependymal cells play in the central nervous system?

<p>They filter blood to make cerebrospinal fluid. (A)</p> Signup and view all the answers

Which of the following best describes the role of the prefrontal cortex?

<p>Regulating emotions and decision-making (A)</p> Signup and view all the answers

What type of behavior would result from damage to integration areas of the left hemisphere?

<p>Aphasia and communication difficulties (B)</p> Signup and view all the answers

What is one reason the blood-brain barrier is critically important?

<p>It prevents rapid changes in extracellular concentrations affecting neuron function. (B)</p> Signup and view all the answers

Which molecules can easily diffuse through the blood-brain barrier?

<p>Fat-soluble molecules like alcohol (D)</p> Signup and view all the answers

What is the likely outcome for sensory information from the left side of the body?

<p>It is processed solely in the right hemisphere. (C)</p> Signup and view all the answers

What characterizes microglia in the central nervous system?

<p>They are involved in immune responses and phagocytosis. (A)</p> Signup and view all the answers

What structure do ependymal cells form around blood vessels in the brain?

<p>Choroid plexuses (B)</p> Signup and view all the answers

Which glial cell type is primarily responsible for supporting neuronal cell bodies in the peripheral nervous system?

<p>Satellite cells (C)</p> Signup and view all the answers

Where are Schwann cells primarily located?

<p>Wrapped around axons in the PNS (D)</p> Signup and view all the answers

Which of the following correctly describes the origins and roles of microglia?

<p>They are derived from white blood cells and act as immune responders. (A)</p> Signup and view all the answers

Why might pharmaceutical companies face challenges when developing drugs for the nervous system?

<p>Drugs must bypass the blood-brain barrier to be effective. (B)</p> Signup and view all the answers

What is the minimum expectation for a patient to demonstrate normal cognitive function in the set generation subtest?

<p>To list at least 10 words in a minute (D)</p> Signup and view all the answers

In the scenario of the young man with Hodgkin's lymphoma, what aspect of memory was primarily affected according to the events described?

<p>Specific event memory (B)</p> Signup and view all the answers

Which of the following describes the role of language in the neurological exam?

<p>It is essential for patient instructions and communication. (A)</p> Signup and view all the answers

What type of aphasia is associated with Broca's area?

<p>Expressive aphasia (D)</p> Signup and view all the answers

What is the primary function of Wernicke's area in the context of language?

<p>To understand the content of language (B)</p> Signup and view all the answers

Conduction aphasia is characterized by difficulty in which area of language processing?

<p>Repetition of spoken language (B)</p> Signup and view all the answers

What is the role of the sensorium in relation to sensory stimuli?

<p>Interprets sensory information consciously and subconsciously. (D)</p> Signup and view all the answers

What cognitive function is evaluated when a patient is asked to follow complex instructions like touching various body parts?

<p>Language understanding (C)</p> Signup and view all the answers

The destruction of the white matter tracts connecting Broca's and Wernicke's areas may lead to which language condition?

<p>Conduction aphasia (B)</p> Signup and view all the answers

Which brain region is associated with maintaining balance by processing proprioceptive information?

<p>Cerebellum (C)</p> Signup and view all the answers

What does expressive aphasia primarily affect in a patient?

<p>Speech fluency and production (D)</p> Signup and view all the answers

What type of memory is generally compromised due to damage in specific brain regions related to the immune system, as seen in the young man's case?

<p>Episodic memory (C)</p> Signup and view all the answers

During the neurological exam, which subtest would directly assess a patient's ability to produce language?

<p>Word generation tasks (D)</p> Signup and view all the answers

Which statement regarding memory loss during the young man's hospital stay is accurate?

<p>The memory loss was temporary and selective to specific events. (C)</p> Signup and view all the answers

Which cranial nerve is primarily responsible for the sense of smell?

<p>Olfactory (B)</p> Signup and view all the answers

What is the main function of the trigeminal nerve?

<p>Motor and sensory functions of the face (A)</p> Signup and view all the answers

Which cranial nerve is responsible for controlling eye movements through the lateral rectus muscle?

<p>Abducens (C)</p> Signup and view all the answers

Which cranial nerve is associated with the motor control of throat muscles and taste sensation?

<p>Glossopharyngeal (B)</p> Signup and view all the answers

The oculomotor nerve has which primary function?

<p>Eye movements (D)</p> Signup and view all the answers

Which side of the brain is primarily associated with language function?

<p>Left side (D)</p> Signup and view all the answers

What condition results from damage to the right side of the brain, affecting the understanding of figurative language?

<p>Aprosodia (A)</p> Signup and view all the answers

What does the term 'diencephalon' mean?

<p>Through brain (A)</p> Signup and view all the answers

Which structure is NOT classified as part of the diencephalon?

<p>Cerebellum (D)</p> Signup and view all the answers

What type of information is primarily relayed through the thalamus?

<p>Sensory information (D)</p> Signup and view all the answers

Which structure is directly involved in regulating homeostasis and connecting with the endocrine system?

<p>Hypothalamus (D)</p> Signup and view all the answers

Which part of the brain is responsible for integrating sensory information from the visual and auditory domains?

<p>Midbrain (D)</p> Signup and view all the answers

What is the primary output structure of the basal nuclei that relays motor commands?

<p>Thalamus (C)</p> Signup and view all the answers

What phenomenon is implied when speech becomes flat or lacks emotional expression due to brain damage?

<p>Aprosodia (A)</p> Signup and view all the answers

How does information travel from the cerebrum to the rest of the nervous system?

<p>Additionally through the thalamus (D)</p> Signup and view all the answers

Which side of the brain predominantly affects the ability to produce verbal responses based on sensory information?

<p>Left side (C)</p> Signup and view all the answers

Which major gland is attached to the hypothalamus and influenced by it?

<p>Pituitary gland (A)</p> Signup and view all the answers

What is the main function of the thalamus in the sensory pathway?

<p>To filter and process sensory information (B)</p> Signup and view all the answers

Which structure serves as the main connection to the cerebellum?

<p>Pons (B)</p> Signup and view all the answers

What is the role of the trigeminal nerve?

<p>Provides cutaneous sensations of the face (C)</p> Signup and view all the answers

Which cranial nerve is involved in lifting the upper eyelid?

<p>Oculomotor Nerve (C)</p> Signup and view all the answers

Which of the following cranial nerves is purely sensory?

<p>Vestibulocochlear Nerve (D)</p> Signup and view all the answers

The vagus nerve contributes to homeostatic control of which area?

<p>Thoracic and upper abdominal cavities (D)</p> Signup and view all the answers

Which cranial nerve has fibers that initiate salivation?

<p>Facial Nerve (D)</p> Signup and view all the answers

What mnemonic sentence corresponds to the basic functions of the cranial nerves?

<p>Some Say Marry Money But My Brother Says Brains Beauty Matter More (D)</p> Signup and view all the answers

Which cranial nerves contain autonomic fibers?

<p>Oculomotor, Facial, Glossopharyngeal (D)</p> Signup and view all the answers

Which of the following cranial nerves controls the muscles in the oral cavity and upper throat?

<p>Glossopharyngeal Nerve (A)</p> Signup and view all the answers

What is the primary function of the hypoglossal nerve?

<p>Control of tongue movements (A)</p> Signup and view all the answers

Which of the following functions is primarily regulated by the pons and medulla?

<p>Cardiovascular and respiratory functions (D)</p> Signup and view all the answers

What is the structural role of the pons in relation to the cerebellum?

<p>It serves as the main connection between the cerebellum and the brain stem. (A)</p> Signup and view all the answers

Which cranial nerve function is associated with the superior colliculus?

<p>Visual tracking and eye movement (C)</p> Signup and view all the answers

What anatomical structure is known for housing the auditory pathways in the midbrain?

<p>Colliculus (B)</p> Signup and view all the answers

Which brain structure is referred to as the 'little brain'?

<p>Cerebellum (D)</p> Signup and view all the answers

Which statement accurately describes the location of the cerebellum?

<p>It is located on the posterior surface of the brain stem. (A)</p> Signup and view all the answers

How does the cerebellum compare incoming information from different sources?

<p>By coordinating input from both the cerebrum and periphery. (C)</p> Signup and view all the answers

What purpose does the reticular formation serve in the brain stem?

<p>Involvement in sleep and wakefulness (D)</p> Signup and view all the answers

What connects the major ascending and descending pathways between the spinal cord and cerebrum?

<p>Brain stem (B)</p> Signup and view all the answers

Where is the inferior olive located in relation to the cerebellum?

<p>It is a nucleus in the medulla sending information to the cerebellum. (A)</p> Signup and view all the answers

Which part of the midbrain is involved in managing visual and auditory space?

<p>Tectum (A)</p> Signup and view all the answers

What is the primary structural composition of the medulla?

<p>Significant amounts of both gray and white matter (A)</p> Signup and view all the answers

What anatomical divisions is the midbrain separated into?

<p>Tectum and tegmentum (B)</p> Signup and view all the answers

Which function is primarily NOT associated with the brain stem?

<p>Processing visual information (B)</p> Signup and view all the answers

What anatomical feature marks the anterior midline of the spinal cord?

<p>Anterior median fissure (B)</p> Signup and view all the answers

Which plate of the neural tube develops into neurons responsible for sensory input?

<p>Alar plate (C)</p> Signup and view all the answers

What is the role of the posterior horn in the spinal cord?

<p>Sensory processing (D)</p> Signup and view all the answers

Which structure is NOT associated with the motor functions of the spinal cord?

<p>Dorsal nerve root (C)</p> Signup and view all the answers

What is the cauda equina and how is it formed?

<p>Spinal nerves that resemble a tail formed from the growth of the vertebral column (B)</p> Signup and view all the answers

The lateral horn of the spinal cord is primarily involved in which of the following?

<p>Sympathetic functions of the autonomic nervous system (D)</p> Signup and view all the answers

What distinguishes the spinal cord regions from the vertebral column?

<p>The spinal cord is shorter than the vertebral column after early childhood (D)</p> Signup and view all the answers

Which of the following structures primarily transmits sensory information to the spinal cord?

<p>Dorsal nerve root (C)</p> Signup and view all the answers

In a cross-section of the spinal cord, what arrangement does the gray matter resemble?

<p>Capital 'H' (D)</p> Signup and view all the answers

What do the white matter columns of the spinal cord carry?

<p>Motor commands and sensory information (D)</p> Signup and view all the answers

What is the function of the anterior horn in the spinal cord?

<p>Sending out motor signals to skeletal muscles (B)</p> Signup and view all the answers

What is the primary distinction between the ascending and descending tracts of white matter?

<p>Ascending tracts transmit sensory information to the brain and descending tracts carry motor commands from the brain (B)</p> Signup and view all the answers

How many spinal nerves emerge from the spinal cord and what are they named for?

<p>31, named for their location along the vertebral column (B)</p> Signup and view all the answers

Which cervical nerve emerges between the first and second cervical vertebrae?

<p>C2 (A)</p> Signup and view all the answers

What is the primary function of the cervical plexus?

<p>To connect to the diaphragm (C)</p> Signup and view all the answers

Which spinal nerve plexus is responsible for nerves that enervate the anterior leg?

<p>Lumbar plexus (D)</p> Signup and view all the answers

What nerve arises from the brachial plexus and continues down the arm?

<p>Radial nerve (D)</p> Signup and view all the answers

Which spinal nerves are classified as intercostal nerves?

<p>T2 through T11 (B)</p> Signup and view all the answers

What best describes a nerve plexus?

<p>A network of nerve fibers (D)</p> Signup and view all the answers

Which nerve from the sacral plexus is primarily associated with sciatica?

<p>Sciatic nerve (A)</p> Signup and view all the answers

How many cranial nerves are classified as purely sensory?

<p>3 (D)</p> Signup and view all the answers

Which cranial nerve is primarily responsible for motor control in the neck?

<p>CNXI (B)</p> Signup and view all the answers

Which structure emerges from the dorsal nerve root of a spinal nerve?

<p>Sensory fibers (C)</p> Signup and view all the answers

What is the function of the phrenic nerve?

<p>Innervation of the diaphragm (C)</p> Signup and view all the answers

Which cranial nerve is responsible for taste sensation?

<p>CNVII (B)</p> Signup and view all the answers

What classification accurately describes the role of mixed cranial nerves?

<p>Both sensory and motor (B)</p> Signup and view all the answers

From which spinal nerves does the lumbar plexus arise?

<p>T12 to L4 (C)</p> Signup and view all the answers

Flashcards

Unipolar Neuron

A neuron with a single process that combines the dendrite and axon.

Bipolar Neuron

A neuron with two processes: one axon and one dendrite extending from opposite sides of the cell body.

Multipolar Neuron

A neuron with one axon and multiple dendrites extending from the cell body.

Astrocyte

A glial cell in the CNS that provides support to neurons; star-shaped.

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Glial Cells (CNS)

Cells supporting neurons in the central nervous system (CNS).

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Glial Cells (PNS)

Cells supporting neurons in the peripheral nervous system.

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Sensory Neuron

A neuron that transmits sensory information from the body to the central nervous system.

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Motor Neuron

A neuron that transmits signals from the central nervous system to muscles or glands.

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Blood-Brain Barrier (BBB)

A protective barrier that prevents many substances in the blood from entering the CNS.

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Astrocyte role in BBB

Astrocytes induce tight junctions between blood vessel cells, making the BBB more restrictive.

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Transcellular processes

The way nutrients (glucose, amino acids) pass through blood vessel cells of the BBB.

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Oligodendrocytes

Glial cells in CNS that insulate axons with myelin.

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Myelin

Fatty insulation around axons that speeds up nerve impulses.

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Microglia

Immune cells in the CNS that remove damaged cells and pathogens.

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Cerebrospinal fluid (CSF)

Fluid that circulates in the CNS, providing nutrients, removing waste and maintaining a stable environment.

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Ependymal cells

Glial cells that filter blood to create CSF.

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Schwann cells

Glial cells in the PNS that insulate axons with myelin.

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Satellite cells

Glial cells in the PNS that support neuron cell bodies.

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CNS Supporting cells

astrocytes, oligodendrocytes, microglia, ependymal cells

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PNS Supporting cells

satellite cells and schwann cells

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Myelin Sheath

A lipid-rich layer surrounding an axon, facilitating faster signal transmission.

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Myelinated Axon

An axon covered by a myelin sheath, which transmits signals faster than an unmyelinated axon.

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Glial Cell

A support cell in the nervous system that produces myelin.

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Cerebrum

A major part of the brain responsible for higher-level functions.

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Cerebral Cortex

The wrinkled outer layer of the cerebrum.

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Longitudinal Fissure

The deep groove separating the two cerebral hemispheres.

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Corpus Callosum

A large bundle of nerve fibers connecting the two cerebral hemispheres.

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Basal Nuclei

Deep brain structures involved in planning and controlling movements

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Gyrus

A ridge on the cerebral cortex.

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Sulcus

A groove between gyri on the cerebral cortex.

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Parietal Lobe

A lobe of the brain involved in processing sensory information.

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Frontal Lobe

A lobe of the brain involved in higher cognitive functions.

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Temporal Lobe

A lobe of the brain involved in processing auditory information.

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Brodmann's Areas

A system of classifying regions of the cerebral cortex based on microscopic anatomy (cytoarchitecture).

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Primary Visual Cortex

Area 17 in the occipital lobe, responsible for initial visual processing.

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Primary Auditory Cortex

Area 22 in the temporal lobe, responsible for initial auditory processing.

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Primary Motor Cortex

Area 4 in the precentral gyrus, responsible for sending signals to move muscles.

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Premotor Cortex

Area 6, responsible for storing learned movement algorithms, instructions for complex movements.

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Localization of Function

Specific brain regions associated with particular functions.

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Occipital Lobe

Brain lobe primarily responsible for visual processing.

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Primary Somatosensory Cortex

The postcentral gyrus (areas 1, 2, and 3) responsible for touch and body senses.

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Primary Motor Cortex

The precentral gyrus, sending signals to move muscles.

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Broca's Area

Brain region primarily responsible for speech production.

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Language Regions

Specific areas of the brain responsible for different aspects of language function, such as comprehension, production, and articulation.

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Primary Cortical Areas

Regions in the cerebral cortex where sensory information is initially processed or where motor commands originate.

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Association Areas

Areas adjacent to primary areas that further process sensory information.

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Multimodal Integration Areas

Regions where different sensory inputs are integrated or processed based on similar functions.

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Integrative Areas

Regions beyond primary and association areas involved in complex tasks.

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Posterior Parietal Cortex

A region between the somatosensory and visual cortex involved in coordinating movement.

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Orientation

A patient's awareness of their surroundings, including time, place, and identity.

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Memory

The ability to store and retrieve information.

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Three-Word Recall Test

A task that assesses short-term memory by having a patient recall three given words after a short interval.

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Remote Memory

Remembering events or information from the distant past.

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Medial Temporal Lobe

A brain region crucial for memory formation and storage, including the hippocampus and amygdala.

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Anterograde Amnesia

The inability to form new memories after an injury or event.

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Retrograde Amnesia

Loss of memories from before an injury or event.

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Episodic Memory

Memory of specific events or personal experiences.

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Procedural Memory

Memory of how to perform skills or actions.

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Short-Term Memory

Memory that holds information briefly in the present.

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Long-Term Memory

Memory that stores information for extended periods.

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Prefrontal Cortex

A brain region involved in planning, decision-making, and working memory.

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Set Generation Test

A mental status exam subtest where patients list words starting with a specific letter, excluding proper nouns, aiming for at least 10 words within 1 minute.

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Hodgkin's Lymphoma

A type of cancer affecting the immune system, potentially leading to antibodies attacking the nervous system.

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Wernicke's Area

A brain region located near the auditory cortex, crucial for language comprehension.

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Aphasia

A condition affecting speech and language abilities due to brain damage.

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Receptive Aphasia

A type of aphasia where speech production is intact, but understanding of language is compromised.

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Expressive Aphasia

A type of aphasia where understanding is intact, but speech production is impaired.

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Conduction Aphasia

A rare type of aphasia affecting the connection between language understanding and production.

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Sensorium

Brain regions involved in receiving and interpreting sensory stimuli.

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Subconscious Sensory Processing

When sensory information is processed by deeper brain regions, not consciously perceived.

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Lateral Sulcus

A deep groove separating the temporal lobe from the parietal and frontal lobes of the brain.

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Praxis

A subtest of sensory perception where patients perform tasks based solely on verbal instructions without demonstration.

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Stereognosis

A task within the gnosis subtest where patients identify objects solely based on touch while blindfolded.

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Graphesthesia

A task within the gnosis subtest where patients identify numbers or letters written on their hand with a dull pointer.

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Gnosis

A subtest of sensory perception that involves two tasks: stereognosis and graphesthesia.

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Judgment

The ability to evaluate situations and make informed decisions.

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Abstract Reasoning

The ability to think conceptually and make connections between ideas.

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Precentral Gyrus

The primary motor cortex, located in the most posterior part of the frontal lobe.

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Phineas Gage

A railroad worker who suffered a severe prefrontal cortex injury, leading to personality changes.

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Prefrontal Lobotomy

A surgical procedure that severs connections to the prefrontal cortex, once used to treat certain psychiatric disorders.

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V Impairment

A language deficit characterized by difficulty using verbs.

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N Impairment

A language deficit characterized by difficulty using nouns.

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Insula

A brain region deep within the cerebral cortex, associated with V impairment.

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Middle and Inferior Temporal Lobe

Brain regions associated with N impairment.

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Active Language

Language that describes actions and processes.

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Split Brain

A condition where the corpus callosum is surgically severed, resulting in two hemispheres that operate independently.

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Left Hemisphere Dominance

The left hemisphere of the brain controls language functions in most individuals.

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Right-Handedness and Left Dominance

Despite left hemisphere language dominance, most people are right-handed.

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Lobotomy Effect

Severe changes in personality and mood can result from damage to the prefrontal cortex.

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Mental Status Exam

A series of tests assessing cognitive functions related to the cerebrum, notably the cerebral cortex.

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Hippocampus

A structure in the temporal lobe vital for forming new memories.

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Amygdala

A structure in the temporal lobe associated with emotional responses.

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Caudate Nucleus

A C-shaped structure in the basal nuclei that runs along the cerebrum, involved in planning and initiating movement.

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Putamen

A structure in the basal nuclei located mainly in the frontal and parietal lobes, working with the caudate to control movement.

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Globus Pallidus

A layered structure in the basal nuclei that lies medial to the putamen, involved in regulating movement.

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Striatum

A collective term for the caudate and putamen, the main input region of the basal nuclei.

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Direct Pathway

A pathway within the basal nuclei that promotes movement by disinhibiting the thalamus.

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Indirect Pathway

A pathway within the basal nuclei that inhibits movement by reinforcing the normal inhibition of the thalamus.

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Substantia Nigra

A brain structure that releases dopamine, influencing the activity of the basal nuclei and thus movement.

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Disinhibition

The removal of an inhibitor, leading to increased activity of the target neuron, as in the direct pathway of the basal nuclei.

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Thalamus

A relay center in the brain that receives information from the basal nuclei and sends it to the cortex, playing a role in movement control.

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What is the role of dopamine in movement?

Dopamine, released by the substantia nigra, modulates the activity of the basal nuclei, influencing the balance between the direct and indirect pathways and ultimately, the likelihood of movement occurring. This is how the basal nuclei help initiate and control movements.

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How do the direct and indirect pathways differ?

The direct pathway, through a shorter route, promotes movement by disinhibiting the thalamus, while the indirect pathway, through a longer route, inhibits movement by reinforcing the normal inhibition of the thalamus.

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What are the major structures of the basal nuclei?

The major structures of the basal nuclei are the caudate, putamen, and globus pallidus. Together, the caudate and putamen form the striatum, which receives input from the cortex. The globus pallidus has two segments, internal (GPi) and external (GPe), which are involved in regulating movement.

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Brain Stem Function

The brain stem controls vital functions like breathing, heart rate, and blood pressure.

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Cranial Nerves: What They Do

Cranial nerves connect the brain stem to the head and neck, carrying sensory information and motor commands.

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Midbrain: Tectum and Tegmentum

The midbrain has two parts: the tectum (roof) and the tegmentum (floor), each with different roles.

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Inferior Colliculus - What Does It Do?

The inferior colliculus, part of the tectum, processes auditory information sent to the brain.

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Superior Colliculus - What Does It Do?

The superior colliculus, part of the tectum, integrates sensory information from sight, sound, and touch.

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Tegmentum - Role in Brain Stem

The tegmentum, found throughout the brain stem, controls functions like heart rate and breathing.

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Pons: The Bridge

The pons, meaning 'bridge' in Latin, connects the cerebellum to the brain stem.

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Medulla: Function

The medulla, a key part of the brain stem, regulates important functions including breathing and heart rate.

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Reticular Formation: Role

The reticular formation, found throughout the brain stem, influences sleep, wakefulness, and alertness.

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Cerebellum: The Little Brain

The cerebellum, meaning 'little brain', coordinates movements and balance.

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Cerebellum: How It Works

The cerebellum compares motor commands from the brain with sensory feedback to keep movements smooth.

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Cerebellum Input and Output

The cerebellum receives information from the brain and periphery, and sends output to the brain stem to refine movements.

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Spinal Cord: Function

The spinal cord acts as a highway carrying messages between the brain and the rest of the body.

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Ascending Pathways

Ascending pathways in the brain stem carry sensory information from the body to the brain.

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Descending Pathways

Descending pathways in the brain stem carry motor commands from the brain to the body.

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Left Brain/Right Brain Myth

The idea that people are either 'left-brained' or 'right-brained' is an oversimplification. While there is some specialization, many functions are distributed across the brain.

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Lateralization of Function

The concept that certain brain functions are primarily associated with one side of the brain, like language on the left and spatial reasoning on the right.

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Split Brain Patients

Individuals who have had their corpus callosum surgically severed to treat severe epilepsy. This disconnects communication between the brain hemispheres.

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Right-Side Brain Damage and Language

Damage to the right side of the brain can affect the use of language, particularly figurative aspects like humor, irony, and metaphors.

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Aprosodia

A condition where a person struggles to understand or express the emotional content of speech due to right-side brain damage.

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Diencephalon

The region of the brain located between the cerebrum and the rest of the nervous system; it acts as a relay station for information.

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Hypothalamus

A region in the diencephalon that regulates essential bodily functions like homeostasis, the autonomic nervous system, and the endocrine system.

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Brain Stem

The central stalk connecting the brain to the spinal cord, composed of the midbrain, pons, and medulla.

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Midbrain

Part of the brain stem that coordinates sensory information from the visual, auditory, and somatosensory systems.

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Pons

A part of the brain stem that serves as the main connection between the cerebellum and other brain regions.

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Medulla

The lowermost part of the brain stem, controlling vital functions such as breathing, heart rate, and blood pressure.

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Autonomic Nervous System Regulation

The hypothalamus regulates the autonomic nervous system, which controls involuntary functions like heart rate, digestion, and breathing.

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Spinal Cord's Structure

The spinal cord retains the tube-like structure of the neural tube during development, whereas the brain expands and forms vesicles.

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Anterior Median Fissure

The anterior midline groove on the surface of the spinal cord.

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Posterior Median Sulcus

The posterior midline groove on the surface of the spinal cord.

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Dorsal Nerve Root

Axons enter the spinal cord through this root, located on the posterior side.

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Ventral Nerve Root

Axons exit the spinal cord through this root, located on the anterior side.

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Sensory vs. Motor Functions

Posterior regions of the spinal cord handle sensory information, anterior regions handle motor commands.

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Basal Plate

The ventral region of the developing neural tube, which forms the anterior part of the spinal cord and gives rise to motor neurons.

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Alar Plate

The dorsal region of the developing neural tube, which forms the posterior part of the spinal cord and gives rise to sensory neurons.

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Spinal Cord Regions

The spinal cord is divided into cervical, thoracic, lumbar, and sacral regions, each corresponding to the vertebrae at that level.

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Cauda Equina

A bundle of spinal nerves that extends below the end of the spinal cord, resembling a horse's tail.

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Gray Matter Horns

The gray matter of the spinal cord is shaped like an 'H' in cross-section, with distinct horns: posterior, anterior, and lateral.

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Posterior Horn Function

The posterior horn of the spinal cord is responsible for processing sensory information.

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Anterior Horn Function

The anterior horn of the spinal cord sends out motor signals to skeletal muscles.

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Lateral Horn Function

The lateral horn, only found in certain regions, is involved in the sympathetic nervous system, controlling things like 'fight or flight' responses.

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Motor Neuron Size

Motor neurons, especially those controlling large muscles, can be very large, with long axons reaching to the target muscle.

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Spinal Nerves

Nerves that emerge from the spinal cord and extend outward to the body, responsible for sensory and motor functions.

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Intervertebral Foramen

The opening between adjacent vertebrae through which spinal nerves exit the vertebral column.

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Nerve Plexus

A complex network of nerve fibers where axons from different spinal nerves reorganize to form systemic nerves.

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Cervical Plexus

A plexus formed by axons from C1-C5 spinal nerves, supplying nerves to the posterior neck, head, and diaphragm.

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Brachial Plexus

A plexus formed by axons from C4-T1 spinal nerves, giving rise to nerves of the arms.

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Lumbar Plexus

A plexus formed by axons from T12-L4 spinal nerves, supplying nerves to the pelvic region and anterior leg.

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Sacral Plexus

A plexus formed by axons from L4, L5, and S1-S4 spinal nerves, supplying nerves to the posterior leg.

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Sciatic Nerve

A major nerve from the sacral plexus formed by the tibial and fibular nerves, extending across the hip joint.

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Cranial Nerves

Nerves directly connected to the brain, primarily responsible for sensory and motor functions of the head and neck.

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Sensory Nerves

Nerves carrying sensory information from the body to the brain.

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Motor Nerves

Nerves carrying motor commands from the brain to muscles.

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Mixed Nerves

Nerves containing both sensory and motor fibers, performing both functions.

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Mnemonic Device

A memory aid or technique used to remember information, often using rhymes or acronyms.

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On Old Olympus' Towering Tops...

A traditional mnemonic rhyme for remembering the names of cranial nerves.

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Sensory Ganglia

Clusters of sensory neuron cell bodies located outside the brain and spinal cord.

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Olfactory Nerve (I)

The first cranial nerve responsible for smell, transmitting sensory information from the nose to the brain.

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Optic Nerve (II)

The second cranial nerve responsible for vision, transmitting sensory information from the eyes to the brain.

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Oculomotor Nerve (III)

The third cranial nerve responsible for controlling eye movements and pupil size.

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Trochlear Nerve (IV)

The fourth cranial nerve responsible for controlling the superior oblique muscle, which rotates the eye.

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Olfactory nerve

The first cranial nerve (CN I), responsible for the sense of smell.

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Optic nerve

The second cranial nerve (CN II), responsible for vision.

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Oculomotor nerve

The third cranial nerve (CN III), responsible for eye movements, pupil constriction, and lifting the upper eyelid.

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Trochlear nerve

The fourth cranial nerve (CN IV), responsible for eye movement, specifically downward and inward rotation.

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Abducens nerve

The sixth cranial nerve (CN VI), responsible for eye movement, specifically outward rotation.

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Trigeminal nerve

The fifth cranial nerve (CN V), responsible for facial sensations and controlling the muscles of chewing.

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Facial nerve

The seventh cranial nerve (CN VII), responsible for facial expressions, taste sensation, and saliva production.

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Vestibulocochlear nerve

The eighth cranial nerve (CN VIII), responsible for hearing and balance.

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Mnemonic for cranial nerve functions

The mnemonic "Some Say Marry Money But My Brother Says Brains Beauty Matter More" helps remember the functions of each cranial nerve.

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Study Notes

Neuron Classification

  • Neurons come in various shapes, crucial for their function
  • Unipolar neurons: Single process merging dendrites and axons forming a T-shape; exclusively sensory neurons; dendrites in periphery, cell bodies in ganglia
  • Bipolar neurons: Two processes (axon and dendrite) extending from opposite sides of the cell body; rare; found in olfactory epithelium and retina
  • Multipolar neurons: Multiple dendrites and one axon extending from the cell body; most common neuron type; include motor neurons and many CNS neurons

Glial Cells of the CNS

  • Astrocytes: Star-shaped; support neurons by maintaining chemical concentrations, removing signaling molecules, responding to damage, and forming the blood-brain barrier (BBB)
  • Oligodendrocytes: "Few branches"; insulate CNS axons with myelin; single oligodendrocyte can myelinate multiple axon segments
  • Microglia: Smaller glial cells; originate as macrophages, part of the CNS's immune response, removing diseased or damaged cells from the CNS
  • Ependymal cells: Filter blood to produce cerebrospinal fluid (CSF); line brain ventricles; move CSF through cilia

Glial Cells of the PNS

  • Satellite cells: Surround neuron cell bodies; support neurons similar to astrocytes in the CNS, but don't form the BBB.
  • Schwann cells: Insulate PNS axons with myelin; a single Schwann cell myelinates only one axon segment, unlike oligodendrocytes which myelinate multiple axons.

Myelin

  • Myelin is a lipid-rich sheath surrounding axons
  • Increases speed of signal transmission along axons; myelinated axons transmit signals faster than unmyelinated axons
  • Formed by glial cells (oligodendrocytes in CNS, Schwann cells in PNS); structure resembles several layers of glial cell membranes wrapped around the axon, reducing cytoplasm between layers.

Spinal Nerves

  • Spinal cord: Part of the CNS; main organ of the nervous system
  • Spinal nerves: 31 pairs; combined sensory and motor axons; emerge from the spinal cord via dorsal and ventral roots
  • Cervical, thoracic, lumbar, sacral: Spinal nerves named according to their vertebral level of emergence
  • Cauda equina: Bundle of spinal nerves resembling a horse's tail; extends below spinal cord.
  • Gray horns: Sensory (posterior), motor (anterior), and autonomic (lateral - thoracic)
  • White columns: Ascending (sensory) and descending (motor) tracts

Cranial Nerves

  • Cranial nerves: 12 pairs (CNI-CNXII); sensory, motor, or mixed; originate from sensory ganglia or motor nuclei in the brainstem.
  • Functions vary, connecting to the head and neck (or in the case of the vagus nerve, organs in the thoracic & abdominal cavities).
  • Mnemonic devices available to aid in remembering them.

Brain Regions

  • Cerebrum: Largest part of the human brain; includes cerebral cortex, corpus callosum
  • Diencephalon: Deep beneath the cerebrum; Thalamus & Hypothalamus. Relays and processes sensory information except for smell. Hypothalamus regulates homeostasis
  • Brain Stem: (midbrain, pons, medulla): Coordinates sensory input, vital functions.
  • Cerebellum: "Little brain"; coordinates movements, compares intended movements to actual movements to make adjustments, 10% of brain mass
  • Subcortical nuclei: (basal nuclei) Influence cortical processes, movement. Direct and indirect pathways process input from cortex, influence movements. Dopamine released by substantia nigra regulates activity in pathways.
  • Frontal, Parietal, Temporal, Occipital Lobes: Specific brain functions reside in different areas
  • Brodmann areas: Microscopic anatomical subdivisions in the cortex that correlate with functional regions
  • Wernicke's and Broca's areas: Language centres
  • Lateralization: Specific functions predominantly located in one cerebral hemisphere (left hemisphere dominant in language)
  • Mental status exam: Assesses cognitive abilities including orientation, memory, language, sensorium, and judgment/reasoning. Specific subtests aid in eliciting neurological behavior

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