13 Questions
Which drug is a competitive nicotinic ganglion blocker with a duration of up to 10 hours?
Mecamylamine
What is the primary mechanism of action of non-depolarizing neuromuscular blockers?
Inhibiting acetylcholine binding
Which type of neuromuscular blocking drug competes with acetylcholine for receptors?
Non-depolarizing blockers
What is the main therapeutic use of Curare (d-Tubocurarine)?
Producing muscle relaxation during surgery
Which neuromuscular blocker blocks sodium ion channels of the end-plate at high doses?
Curare
What is the pharmacokinetic route of administration for Succinylcholine?
Intravenous (IV)
Which drug directly inhibits the release of calcium ions from the sarcoplasmic reticulum?
Dantrolene
Which of the following statements about ganglionic blockers is FALSE?
Can be effectively used as a neuromuscular antagonist
What is the primary neurochemical effect of nicotine on ganglia and striated muscle?
Depolarizes ganglia inducing muscular paralysis
Which of the following drugs is a short-acting competitive nicotinic ganglion blocker used for emergency lowering of blood pressure?
Trimethaphan
In comparison to ganglionic blockers, how do cholinergic antagonists primarily act on the nervous system?
By blocking acetylcholine receptors in autonomic ganglia
Which of the following is a FALSE statement about muscle paralysis induced by non-depolarizing blockers?
They lead to depolarization of the muscle membrane
Which drug is a non-selective nicotinic antagonist that acts on autonomic ganglia and was historically used as an antihypertensive agent?
Mecamylamine
Learn about neuromuscular blocking drugs, their classification, mechanism of action, and clinical uses. Explore the differences between non-depolarizing and depolarizing agents, and their role during surgical procedures.
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