Neuromuscular Blocking Drugs Overview
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Questions and Answers

Which drug is a competitive nicotinic ganglion blocker with a duration of up to 10 hours?

  • Succinylcholine
  • Curare
  • Dantrolene
  • Mecamylamine (correct)
  • What is the primary mechanism of action of non-depolarizing neuromuscular blockers?

  • Blocking sodium ion channels
  • Promoting muscle contraction
  • Inhibiting acetylcholine binding (correct)
  • Enhancing acetylcholine release
  • Which type of neuromuscular blocking drug competes with acetylcholine for receptors?

  • Non-depolarizing blockers (correct)
  • Succinylcholine
  • Depolarizing blockers
  • Dantrolene
  • What is the main therapeutic use of Curare (d-Tubocurarine)?

    <p>Producing muscle relaxation during surgery</p> Signup and view all the answers

    Which neuromuscular blocker blocks sodium ion channels of the end-plate at high doses?

    <p>Curare</p> Signup and view all the answers

    What is the pharmacokinetic route of administration for Succinylcholine?

    <p>Intravenous (IV)</p> Signup and view all the answers

    Which drug directly inhibits the release of calcium ions from the sarcoplasmic reticulum?

    <p>Dantrolene</p> Signup and view all the answers

    Which of the following statements about ganglionic blockers is FALSE?

    <p>Can be effectively used as a neuromuscular antagonist</p> Signup and view all the answers

    What is the primary neurochemical effect of nicotine on ganglia and striated muscle?

    <p>Depolarizes ganglia inducing muscular paralysis</p> Signup and view all the answers

    Which of the following drugs is a short-acting competitive nicotinic ganglion blocker used for emergency lowering of blood pressure?

    <p>Trimethaphan</p> Signup and view all the answers

    In comparison to ganglionic blockers, how do cholinergic antagonists primarily act on the nervous system?

    <p>By blocking acetylcholine receptors in autonomic ganglia</p> Signup and view all the answers

    Which of the following is a FALSE statement about muscle paralysis induced by non-depolarizing blockers?

    <p>They lead to depolarization of the muscle membrane</p> Signup and view all the answers

    Which drug is a non-selective nicotinic antagonist that acts on autonomic ganglia and was historically used as an antihypertensive agent?

    <p>Mecamylamine</p> Signup and view all the answers

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