6 Questions
What is the primary mechanism of action of small doses of non-depolarizing neuromuscular blocking agents (NMBs)?
Competitive antagonism of Ach at Nm receptors at the neuromuscular junction (NMJ)
Which adverse effect is associated with tubocurarine, a prototype non-depolarizing NMB?
Histamine release leading to bronchoconstriction
What effect does a large dose of non-depolarizing NMB have on the neuromuscular junction?
It blocks presynaptic Nn receptors, leading to decreased Ach release
Which bacteria is most commonly associated with causing necrotizing fasciitis?
Streptococcus pyogenes
What is the primary reason for calling the bacteria causing necrotizing fasciitis 'flesh-eating bacteria'?
Production of streptococcal pyrogenic exotoxins A, B & C
Which type of bacteria causing necrotizing fasciitis is commonly found in the oral or enteric environment?
Anaerobes
This quiz covers the mechanism of action of non-depolarizing neuromuscular blocking agents (NMBs) and their adverse effects. It includes information on the competitive antagonism of acetylcholine at the Nm receptors and the blockade of presynaptic Nn receptors.
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