40 Questions
What is the most common inherited progressive peripheral neuropathy?
Charcot-Marie-Tooth Disease
What is the primary characteristic of Type I CMT?
Demyelinating condition that slows nerve conduction velocity
What is the primary cause of muscle weakness in CMT?
Abnormal peripheral myelin protein
What is the typical age of onset for Type I CMT?
First or second decade of life
What is the primary treatment approach for CMT?
Non-operative physical therapy and occupational therapy
What is the primary goal of medical management for type 1 DM in the context of diabetic polyneuropathy?
Optimized glycemic control
Which of the following is NOT a potential cause of lumbosacral plexopathy?
Charcot-Marie-Tooth disease
What is a common symptom of lumbosacral plexopathy?
Low back and/or leg pain
What type of medications are commonly prescribed for neuropathic pain in diabetic polyneuropathy?
Tricyclic antidepressants and anticonvulsants
What is the primary goal of multidisciplinary team management in diabetic polyneuropathy?
Prevention and management of diabetic foot complications
What is the primary symptom of patients with pregnancy-related postoperative plexopathy?
Unilateral pain in the proximal thigh
What is the best diagnostic test for evaluating the lumbar-sacral plexus?
MRI with/out gadolinium contrast
Which type of plexopathy often presents without pain, only with weakness and sensory changes?
Radiation plexopathy
What is the characteristic of Hyperkinetic Movement Disorders (HMDs)?
Abnormal, involuntary movements overlapped to normal motor activity
What is a potential complication of lumbar plexopathy?
All of the above
What is the estimated percentage of patients with diabetes that are affected by diabetic neuropathy?
51%
What is a major risk factor for diabetic neuropathy?
Poor glycemic control
What is the most common type of diabetic neuropathy?
Distal symmetric polyneuropathy
What is a possible complication of diabetic neuropathy?
Lower limb amputation
What is the underlying cause of diabetic neuropathy?
Nerve inflammation caused by hyperglycemia
What is the characteristic of Myoclonus movements?
Sudden and brief
What is the term for Hyperkinetic movement disorders classified according to body distribution?
Body Distribution
How is Dystonia classified based on the body parts affected?
Focal, Segmental, Multifocal, and Generalized
What are the five major types of Hyperkinetic Movement Disorders?
Tremors, Chorea, Dystonia, Myoclonus, and Tics
What is Chorea characterized by?
Excessive, spontaneous, irregularly timed, non-repetitive, and abrupt movements
What percentage of diabetic neuropathy cases are asymmetrical or focal syndromes?
14-30%
What is a common symptom of diabetic neuropathy in the hands or feet?
Numbness
What is the purpose of testing gross light touch and pinprick sensation in diabetic neuropathy diagnosis?
To assess sensory function
What is the classification of diabetic neuropathy that affects the autonomic nervous system?
Autonomic neuropathy
What is the staging of diabetic neuropathy characterized by severe symptomatic polyneuropathy and inability to heel walk?
N2b
What is the primary characteristic of tics?
Involuntary, rapid, abrupt, repetitive, recurrent, and nonrhythmic movements or vocalizations
What is dystonia characterized by?
Sustained muscle contractions and abnormal trunk, neck, face, arms, and legs postures
What is an important aspect of diagnosing movement disorders?
History and neurologic examination
What is a goal of management for movement disorders?
Gait re-education and balance retraining
What is a characteristic of tremors?
Rhythmic and oscillatory movements
What is important to consider when diagnosing movement disorders?
Both neurological and non-neurological conditions
What is another term for hyperkinetic movement disorder?
Chorea
What is a goal of management for movement disorders related to gait?
All of the above
What is a feature of tics?
Involuntary, rapid, abrupt, repetitive, recurrent, and nonrhythmic movements or vocalizations
What is a goal of management for movement disorders related to respiratory function?
Respiratory function training
This quiz covers Charcot-Marie-Tooth disease, an inherited peripheral neuropathy, its causes, symptoms, and effects on the muscles and bones. Learn about the patho-anatomy of the disease and its impact on daily life.
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