Neurologic Symptoms and COVID-19 PCR Testing
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Questions and Answers

What is the potential drawback mentioned regarding the diagnosis of prion disease (PrD) in COVID-19 patients?

  • False-positive results due to sampling errors
  • False-negative results due to sampling errors (correct)
  • Lack of correlation between PrD and COVID-19
  • Difficulty in establishing a timeline of event development

    • According to the case report discussed in the text, what was the time between the onset of COVID-19 symptoms and the manifestation of Creutzfeldt-Jakob Disease (CJD) symptoms?

  • The onset of CJD symptoms coincided with COVID-19 symptoms
  • The onset of CJD symptoms preceded COVID-19 symptoms
  • The timeline is unclear as the patient was admitted after a fall (correct)
  • The onset of CJD symptoms followed COVID-19 symptoms

    • Which of the following is hypothesized in the text as a potential mechanism for the development of prion disease in COVID-19 patients?

  • COVID-19-related neurodegeneration leading to Parkinson's disease
  • Excessive protein secretions contributing to protein misfolding
  • Gut microbiota provoking protein misfolding (Braak hypothesis)
  • SARS-CoV-2 S1 spike proteins possessing prion-like properties (correct)

    • What is the average diagnostic success rate of brain biopsies for prion disease mentioned in the meta-analysis?

    <p>54%</p> Signup and view all the answers

    Which of the following statements is NOT supported by the information provided in the text?

    <p>The exact correlation between COVID-19 and prion disease has been established</p> Signup and view all the answers

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