Neurologic Disorders of the Larynx
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Questions and Answers

What type of dystonia is spasmodic dysphonia classified as?

  • Inherited dystonia
  • Degenerative dystonia
  • Structural dystonia
  • Idiopathic focal dystonia (correct)
  • Which of the following describes dopa-responsive Parkinsonism in relation to dystonia?

  • It cannot exist alongside any other symptoms.
  • It is exclusively a degenerative condition.
  • It is always associated with genetic mutations.
  • It can manifest with additional signs including dystonia. (correct)
  • What is a potential consequence of long-term injections used in treating dystonia?

  • Complete recovery of muscle strength
  • Increased muscle activity
  • Permanent nerve damage
  • Unknown long-term effects (correct)
  • Which feature is associated with short-term variations of motor symptoms?

    <p>Combined symptoms with other features</p> Signup and view all the answers

    How is heritability classified concerning dystonia conditions?

    <p>Mixed heritability including both inherited and acquired</p> Signup and view all the answers

    In relation to diagnostic imaging, which statement is true for dystonia-related pathology?

    <p>Some cases may not exhibit degenerative or structural pathology.</p> Signup and view all the answers

    Which type of symptoms can be involved with paroxysmal forms of dystonia?

    <p>Intermittent and sudden movements</p> Signup and view all the answers

    Which condition is NOT typically associated with idiopathic dystonia?

    <p>Cognition-related challenges</p> Signup and view all the answers

    What percentage of patients showed some persistent improvement three years after surgical treatment according to the review by Aronson and DeSanto?

    <p>36%</p> Signup and view all the answers

    Which procedure has outcomes similar to chemodenervation with botulinum toxin for ADSD?

    <p>Selective laryngeal adductor denervation-reinnervation (SLAD-R)</p> Signup and view all the answers

    What muscle is specifically targeted for injections in cases of adductor spasmodic dysphonia (ABSD)?

    <p>Posterior cricoarytenoid (PCA) muscle</p> Signup and view all the answers

    What is the most consistent management approach for symptoms of laryngeal disorders as per the content?

    <p>Use of an individualized regimen of chemodenervation with botulinum toxin</p> Signup and view all the answers

    During the diagnostic process for laryngeal disorders, what activity does a physician instruct the patient to maximize the function of the PCA muscle?

    <p>Sniff</p> Signup and view all the answers

    What are the primary clinical manifestations of primary torsion dystonia?

    <p>Dystonia and tremor</p> Signup and view all the answers

    What complication may some patients with adductor spasmodic dysphonia experience during treatment?

    <p>Supraglottic squeeze</p> Signup and view all the answers

    How is the botulinum toxin administered to the PCA muscle?

    <p>Percutaneously through the cricothyroid membrane</p> Signup and view all the answers

    Which form of dystonia affects a single isolated body region?

    <p>Focal dystonia</p> Signup and view all the answers

    What percentage of patients reportedly achieved a persistent normal voice following surgery for laryngeal conditions?

    <p>3%</p> Signup and view all the answers

    Which of the following is NOT a common clinical sign associated with lesions in the cortex?

    <p>Tremor</p> Signup and view all the answers

    In which age group does dystonia commonly present according to the classification criteria?

    <p>3–12 years</p> Signup and view all the answers

    Which subtype of dystonia involves two or more contiguous regions of the body?

    <p>Segmental dystonia</p> Signup and view all the answers

    What is the defining characteristic of generalized dystonia?

    <p>Involves trunk and two other sites</p> Signup and view all the answers

    Which condition is characterized by involuntary eye closure?

    <p>Blepharospasm</p> Signup and view all the answers

    What type of vocal disorder is linked with spasmodic movements affecting laryngeal function?

    <p>Spasmodic dysphonia</p> Signup and view all the answers

    Which dimension for classifying dystonia refers to the course of the disease?

    <p>Temporal pattern</p> Signup and view all the answers

    Which neurological sign is most commonly associated with lesions in the brainstem?

    <p>Flaccid paralysis</p> Signup and view all the answers

    What is a primary safety consideration for surgeons when using lasers during procedures?

    <p>Understanding the interaction of lasers with different tissues</p> Signup and view all the answers

    Which type of emission occurs when a photon stimulates an excited atom to release an additional photon?

    <p>Stimulated emission</p> Signup and view all the answers

    Which statement correctly describes the state of atoms before photon absorption?

    <p>Atoms are in a low energy state</p> Signup and view all the answers

    What should surgeons become familiar with to choose the correct type of laser?

    <p>Basic fundamentals of laser physics</p> Signup and view all the answers

    Which process describes the release of a photon from an atom in an excited state without external stimulation?

    <p>Spontaneous emission</p> Signup and view all the answers

    What is a key reason for establishing separate credentialing for each laser used by surgeons?

    <p>To ensure proper safety protocols are followed</p> Signup and view all the answers

    Which laser was developed first for use in otolaryngology?

    <p>Carbon dioxide (CO2) laser</p> Signup and view all the answers

    What is the primary function of the articulated arm developed by Polanyi in 1968?

    <p>To deliver laser radiation to remote targets</p> Signup and view all the answers

    Which type of laser was notably emphasized for its therapeutic applications in dermatology?

    <p>Nd:YAG laser</p> Signup and view all the answers

    What was one of the first investigations into laser interaction with biological tissues focused on?

    <p>Damage caused by lasers on rabbit retina and iris</p> Signup and view all the answers

    What application of laser technology contributes to enhancing communication in everyday life?

    <p>Laser printers and optical discs</p> Signup and view all the answers

    Why is laser light considered the brightest monochromatic light?

    <p>It is highly focused and can emit a single color</p> Signup and view all the answers

    Which is a safety consideration highlighted in the use of lasers in surgery?

    <p>Possible hazards from laser exposure</p> Signup and view all the answers

    What is the primary advantage of using the Tm:YAG laser compared to the CO2 laser?

    <p>Better hemostasis during surgical procedures</p> Signup and view all the answers

    Which characteristic best describes continuous wave lasers?

    <p>They are always on, providing stable operation.</p> Signup and view all the answers

    What is a significant disadvantage of using the Tm:YAG laser compared to the CO2 laser?

    <p>Less precision in tissue cutting</p> Signup and view all the answers

    What is the main characteristic of flashlamp-pumped pulsed dye lasers?

    <p>They can operate at varying pulse durations between 0.5 to several hundred milliseconds.</p> Signup and view all the answers

    In which aspect does the Tm:YAG laser demonstrate greater effectiveness compared to electrocautery?

    <p>Improved hemostatic capabilities</p> Signup and view all the answers

    What effect does the larger dispersion of thermal effects from the Tm:YAG laser have?

    <p>Creates a broader thermal injury zone</p> Signup and view all the answers

    Which of the following best describes the relationship between pulsed dye lasers and conventional continuous lasers?

    <p>Pulsed dye lasers result in less peripheral damage than continuous lasers.</p> Signup and view all the answers

    What is the primary application of the Tm:YAG laser in a surgical setting?

    <p>Office endolaryngeal surgery</p> Signup and view all the answers

    Study Notes

    Neurologic Disorders of the Larynx

    • Neurologic larynx disorders can be focal or systemic
    • Clinical examination helps pinpoint the lesion's location
    • Hyperfunctional disorders include dystonia, myoclonus, essential tremor, stuttering, and muscle tension dysphonia
    • Hypofunctional disorders encompass vocal fold paresis/paralysis and central causes like Parkinson's disease, multiple sclerosis, and neuromuscular junction disorders
    • Spasmodic dysphonia is an idiopathic laryngeal dystonia, causing halting or breathy speech
    • Botulinum toxin is a key treatment for spasmodic dysphonia and other dystonias
    • Vocal fold paresis can arise from trauma, tumors, neurological or medical issues
    • Vocal fold positioning varies in presentation

    Laryngeal Manifestations of Neurologic Diseases

    • Cortical lesions (strokes, tumors, trauma) can impair speech and vocalization due to bilateral laryngeal cortex representation
    • Extrapyramidal system defects lead to inappropriate muscle tension, tremors, and spasms, affecting voice quality
    • Cerebellar lesions cause generalized motor coordination deficits, resulting in "scanning speech"
    • Brainstem lesions induce flaccid paralysis influencing multiple cranial motor outputs
    • Diffuse central nervous system lesions (multiple sclerosis, ALS) produce myriad signs and symptoms in patients with movement disorders (akinesia, bradykinesia, hyperkinesia)

    Hyperfunctional Disorders: Dystonia

    • Dystonia is a syndrome characterized by sustained skeletal muscle contractions, causing repetitive twisting movements or abnormal postures
    • Dystonia types are classified, impacting prognosis and management
    • Focal dystonia affects one body region; segmental involves adjacent regions, multifocal disparate regions, hemidystonia half the body, and generalized the entire body (including the larynx).
    • Dystonia can start at any age
    • The initial onset has a bimodal distribution with peaks at 8 years and 42 years, roughly

    Botulinum Toxin Therapy

    • Botulinum toxin type A (Botox) or type B (Myobloc) is commonly used
    • Injections improve speech in adductor spasmodic dysphonia (ADSD) cases (thyroarytenoid-vocalis muscle complex) and abductor (posterior cricoarytenoid) cases
    • Injections are guided by EMG for precise placement and targeted muscle improvement.
    • Adverse effects are mostly mild, including temporary breathy voice, hoarseness, or swallowing issues.

    Pseudobulbar Palsy

    • Results from bilateral corticobulbar damage.
    • Characterized by muscle spasticity and hyperreflexia of various parts of the head and neck
    • Voice is harsh, strained, and strangled, often with associated hypernasality and slow speech.

    Myoclonus

    • Rhythmic contractions (1-2 Hz) of the soft palate, pharynx, and larynx.
    • Can affect eyes as well.
    • Treatment with Botulinum Toxin in certain cases

    Essential Tremor

    • Involuntary, rhythmic movements (6–8 Hz) of parts of the body, often including the hands, head, and voice.
    • Classified based on clinical characteristics and etiology (genetic, acquired, idiopathic)
    • Essential Tremor can manifest in a tremulous or "wavy" voice

    Stuttering

    • Stuttering involves abnormal, involuntary, and excessive use of speech muscles, causing dysfluency
    • Stuttering impacts speech subsystems (respiratory, phonatory, articulatory), creating muscle tension issues
    • Speech therapy and altered feedback systems (like electronic in-ear devices) are often used to manage stuttering

    Hypo-functional Disorders

    • Central causes: Vocal fold paresis (including syringobulbia, Arnold-Chiari malformations); stroke; and lower motor neuron diseases
    • Peripheral nerve injury/compression
    • Neuromuscular junction disorders: Myasthenia gravis, Eaton-Lambert disease affecting muscle fatigue
    • Poliomyelitis (though rare today due to vaccines); postpolio syndrome leading to potential vocal cord issues.
    • Myopathies (e.g., dermatomyositis) affecting muscles
    • Medullary disorders (ALS, primary lateral sclerosis): impacting motor neurons in the brainstem, leading to potential flaccid paralysis and vocal problems.
    • Multiple Sclerosis (MS) causing varied problems that include potential vocal dysfunctions, impacting ability to speak or swallow,

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    Description

    Explore the various neurologic disorders affecting the larynx, including both hyperfunctional and hypofunctional conditions. This quiz covers diagnoses, clinical examinations, and treatment options such as botulinum toxin. Test your knowledge on the impact of neurologic diseases on vocalization and associated laryngeal manifestations.

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