Neuroglial Cells of the CNS

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Questions and Answers

If a patient's neural tissue is showing signs of increased foreign material, which of the following cells would be expected to be most active?

  • Ependymal cells
  • Astrocytes
  • Oligodendrocytes
  • Microglial cells (correct)

A researcher is studying the structural organization of the central nervous system (CNS). Which type of neuroglial cell should they focus on due to its role in binding axon clusters?

  • Ependymal cells
  • Microglial cells
  • Astrocytes
  • Oligodendrocytes (correct)

Damage to which type of neuroglial cell would most likely affect the composition and circulation of cerebrospinal fluid (CSF)?

  • Oligodendrocytes
  • Ependymal cells (correct)
  • Astrocytes
  • Microglial cells

Which neuroglial cell type contributes to the blood-brain barrier and regulates the external environment of neurons in the CNS?

<p>Astrocytes (A)</p> Signup and view all the answers

Which of the following is a primary function of oligodendrocytes in the central nervous system (CNS)?

<p>Forming the myelin sheath around axons (B)</p> Signup and view all the answers

A lesion in the spinal cord disrupts the circulation of cerebrospinal fluid. Which of the following cell types is most likely affected by this lesion?

<p>Ependymal cells (C)</p> Signup and view all the answers

Following a stroke, which neuroglial cells would be expected to proliferate to remove dead or damaged tissue in the CNS?

<p>Microglial cells (A)</p> Signup and view all the answers

If a disease damages the myelin sheaths in the CNS, which cell type is most likely being targeted by the disease process?

<p>Oligodendrocytes (D)</p> Signup and view all the answers

In a scenario where the blood-brain barrier is compromised, leading to increased permeability and inflammation, which cells are most likely to be involved in responding to and attempting to repair the damage?

<p>Astrocytes and Microglial cells (C)</p> Signup and view all the answers

Why might damage to oligodendrocytes, which form myelin, lead to slower nerve impulse transmission?

<p>Myelin sheaths insulate axons, speeding up signal conduction. (A)</p> Signup and view all the answers

Flashcards

Oligodendrocytes

Forms myelin around axons in the CNS, can myelinate segments of several axons, and ties clusters of axons together for structural organization.

Microglial cells

Least numerous and smallest neuroglial cells; phagocytose foreign/degenerate material and circulate through neural tissue.

Astrocytes

Largest, most numerous neuroglial cells; regulate external environment, maintain the blood-brain barrier, provide structural support and nutrients.

Ependymal cells

Line the CSF-filled ventricles in the brain and central canal of spinal cord; assist in producing and circulating cerebrospinal fluid.

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Study Notes

  • Four main types of neuroglial cells exist in the central nervous system (CNS).

Oligodendrocytes

  • Forms myelin around axons, with each cell capable of myelinating segments of several axons
  • Can tie clusters of axons together, thus plays a role in structural organization

Microglial Cells

  • Least numerous and smallest of the neuroglial cells
  • Capable of phagocytosing any foreign or degenerate material
  • Circulate through the neural tissue

Astrocytes

  • Largest and most numerous of the neuroglial cells
  • Regulate external environment
  • Play a role in maintaining the blood-brain barrier
  • Give both structural support and nutrients

Ependymal Cells

  • Lines the CSF-filled ventricles in the brain and the central canal of the spinal cord, which is a simple cuboidal epithelium that lacks a basement membrane
  • Assists in producing and circulating cerebrospinal fluid

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