Neuroendocrine System Functions Quiz
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Questions and Answers

Which neurotransmitter is the primary one for postganglionic sympathetic adrenergic nerves?

  • Epinephrine
  • Norepinephrine (correct)
  • Dopamine
  • Acetylcholine

What is the term used for a neuron when its transmission is mediated by acetylcholine?

  • Adrenergic
  • Dopaminergic
  • Norepinephrinergic
  • Cholinergic (correct)

Which receptor type is part of the parasympathetic system and is innervated by acetylcholine?

  • Nicotinic receptor
  • Dopaminergic receptor
  • Muscarinic receptor (correct)
  • Adrenergic receptor

What is the neurotransmitter for nicotinic receptors?

<p>Acetylcholine (C)</p> Signup and view all the answers

What is the primary therapeutic use of epinephrine?

<p>Bronchial Asthma &amp; Heart block or cardiac arrest (A)</p> Signup and view all the answers

Which receptor type predominates in the therapeutic use of epinephrine for anaphylactic shock?

<p>Beta receptor (C)</p> Signup and view all the answers

What is the primary therapeutic use of norepinephrine?

<p>Acute hypotension in a hemodynamically unstable patient (B)</p> Signup and view all the answers

Which receptor type predominantly affects vasoconstriction in the cardiovascular system?

<p>Alpha-1 receptor (D)</p> Signup and view all the answers

What is the action of dopamine on D1 receptors?

<p>Vasodilation of renal and splanchnic beds (C)</p> Signup and view all the answers

Which category of adrenergic drugs acts on receptors stimulated by epinephrine and norepinephrine?

<p>Direct Acting Adrenergic Agonists (B)</p> Signup and view all the answers

What is the action of isoproterenol on the pulmonary system?

<p>Bronchodilation (D)</p> Signup and view all the answers

Which agent causes release of norepinephrine from presynaptic terminals and increases NE release?

<p>Amphetamines (A)</p> Signup and view all the answers

Which system controls the brain's internal regulation and is essential for survival?

<p>Endocrine system (C)</p> Signup and view all the answers

Where do specialized endocrine cells secrete hormones?

<p>Into the bloodstream (A)</p> Signup and view all the answers

Which molecules rapidly diffuse across the synaptic cleft between neurons?

<p>Neurotransmitters (C)</p> Signup and view all the answers

What do histamines and prostaglandins serve as examples of?

<p>Local mediators (C)</p> Signup and view all the answers

Which division of the nervous system carries signals away from the brain and spinal cord to peripheral tissue?

<p>Efferent division (D)</p> Signup and view all the answers

What do somatic efferent neurons control voluntarily?

<p>Contraction of skeletal muscles (D)</p> Signup and view all the answers

Where does the spinal cord finish, according to the text?

<p>At L1 (D)</p> Signup and view all the answers

What is the function of a preganglionic neuron in the autonomic nervous system?

<p>To carry signals away from the brain and spinal cord (B)</p> Signup and view all the answers

What is the mechanism of action of adrenergic agonists?

<p>Enhancement of sympathetic activity by blocking the Na/K pump required for reuptake of norepinephrine (C)</p> Signup and view all the answers

Which of the following best describes the effect of alpha 2 receptor activation?

<p>Mediated by inhibition of adenylyl cyclase and a fall in the levels of intracellular cAMP (C)</p> Signup and view all the answers

What are the characteristics of catecholamines as adrenergic agonists?

<p>High potency and rapid inactivation by catechol-Omethyltransferase (COMT) and monoamine oxidase (MAO) (C)</p> Signup and view all the answers

How do noncatecholamines differ from catecholamines as adrenergic agonists?

<p>They lack the catechol hydroxyl groups and have longer half-lives (D)</p> Signup and view all the answers

Which structural feature contributes to the high potency of catechol derivatives in directly activating alpha or beta receptors?

<p>The number and location of OH substitutions on the benzene ring (A)</p> Signup and view all the answers

Which adrenergic drug has an alternative use for shock treatment and may be used to treat acute hypotension?

<p>Metaraminol (A)</p> Signup and view all the answers

What is the role of monoamine oxidase (MAO) in the inactivation of noncatecholamines?

<p>It is an important route of detoxification, leading to prolonged duration of action (C)</p> Signup and view all the answers

What is a common side effect associated with adrenergic agonists?

<p>Arrhythmias (A)</p> Signup and view all the answers

Which step results from the activation of alpha 1 receptor through G protein activation of phospholipase C?

<p>Generation of inositol-1,4,5-trisphosphate (IP₃) from phosphatidylinositol (B)</p> Signup and view all the answers

What is the effect of ephedrine as an adrenergic agonist?

<p>Induction of norepinephrine release from presynaptic terminals and activation of adrenergic receptors in post synaptic membranes (A)</p> Signup and view all the answers

What is the role of desensitization in adrenergic receptors?

<p>Fall in levels of intracellular cAMP due to inhibition by alpha 2 receptor activation (D)</p> Signup and view all the answers

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