Neuroanesthesia Monitoring
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Questions and Answers

What is the primary goal of neuro anesthesia as it relates to brain function?

  • Induce complete anesthesia without any cerebral activity
  • Provide adequate oxygen and glucose to meet metabolic demands (correct)
  • Minimize muscle relaxation during procedures
  • Reduce blood flow to the brain
  • Which methods are used specifically for monitoring blood flow to the brain (CBF and ICP)?

  • Laser doppler blood flow (correct)
  • Nitrous oxide wash-in (correct)
  • Radioactive xenon clearance (correct)
  • ICP monitors (e.g. intraventricular catheters) (correct)
  • What type of monitoring would directly assess the metabolic state of brain tissue?

  • Electroencephalography
  • Jugular venous oximetry (correct)
  • Intracranial pressure monitoring
  • Evoked potentials
  • Which of the following techniques are primarily used for monitoring brain function during anesthesia? (select all that apply)

    <p>Electroencephalography (EEG)</p> Signup and view all the answers

    What are beta waves characterized by in terms of frequency and amplitude when a person is awake?

    <p>High frequency, low amplitude</p> Signup and view all the answers

    Which statement best describes the relationship between EEG activity and metabolic conditions?

    <p>EEG activity reflects brain's wakefulness and can diminish with decreased blood flow.</p> Signup and view all the answers

    In the International 10-20 system, odd-numbered electrodes are positioned in which hemisphere?

    <p>Left hemisphere</p> Signup and view all the answers

    Which type of brainwave is associated with children during normal sleep and not associated with adults?

    <p>Theta waves - low frequency</p> Signup and view all the answers

    What happens to beta wave activity in response to hypoxia or ischemia?

    <p>Beta activity transiently increases as a compensatory mechanism for blood flow.</p> Signup and view all the answers

    Which of the following are the 3 categories of neurophysiologic monitoring? (Select all that apply)

    <p>Function</p> Signup and view all the answers

    Which of the following devices are used for monitoring cerebral metabolism? (Select all that apply)

    <p>Intercerebral PO2 electrode</p> Signup and view all the answers

    Which of the following are NOT recorded by EEG? (Select all that apply)

    <p>Subcortical structures</p> Signup and view all the answers

    Which cells are primarily responsible for producing the electrical activity that is detected by an EEG?

    <p>Pyramidal cells in the cerebral cortex</p> Signup and view all the answers

    What comprises the electrical activity recorded by EEG?

    <p>Excitatory and inhibitory postsynaptic potentials of pyramidal cells</p> Signup and view all the answers

    What is the nasion?

    <p>The depressed area between the eyes</p> Signup and view all the answers

    What is the inion?

    <p>The lowest point of the skull</p> Signup and view all the answers

    When are the medium frequency, higher amplitude alpha waves typically seen?

    <p>When awake but restful</p> Signup and view all the answers

    Which waves are associated with deep coma, anesthesia, and hypoxia?

    <p>Delta waves</p> Signup and view all the answers

    What type of wave activity is primarily observed in awake EEG recordings?

    <p>Beta waves</p> Signup and view all the answers

    What can cause EEG depression? (Select all that apply)

    <p>Decrease in blood flow</p> Signup and view all the answers

    What are epileptiform patterns and spikes indicative of on an EEG?

    <p>Epilepsy</p> Signup and view all the answers

    What is burst suppression in EEG patterns characterized by?

    <p>Periods of high voltage electrical activity alternating with periods of no brain activity</p> Signup and view all the answers

    What are causes of burst suppression? (Select all that apply)

    <p>Anesthesia</p> Signup and view all the answers

    What does unilateral burst suppression indicate?

    <p>Cerebral ischemia</p> Signup and view all the answers

    What is the gold standard for EEG monitoring that is rarely achieved in the OR?

    <p>16 channels</p> Signup and view all the answers

    What occurs to the EEG as the level of anesthesia deepens?

    <p>The EEG waveforms decrease in frequency and have a higher amplitude (i.e., slower and taller)</p> Signup and view all the answers

    What occurs as a result of most IV anesthetics and inhalation agents?

    <p>Dose-dependent EEG depression and burst suppression</p> Signup and view all the answers

    How does hypothermia alter EEG readings?

    <p>It leads to burst suppression patterns due to decreased CMRO2</p> Signup and view all the answers

    How does ketamine affect EEG readings?

    <p>Increased cortical activity that causes an underestimation of anesthetic depth</p> Signup and view all the answers

    Which agent does not reduce BIS when used as a sole agent?

    <p>Nitrous Oxide (N2O)</p> Signup and view all the answers

    Which agent is known to cause increased beta wave activity?

    <p>Nitrous Oxide (N2O)</p> Signup and view all the answers

    Which of the following brain wave patterns are prevalent during general anesthesia? (Select all that apply)

    <p>Theta waves</p> Signup and view all the answers

    During which stages of anesthesia is increased beta wave activity observed?

    <p>Induction and light anesthesia</p> Signup and view all the answers

    At what minimum alveolar concentration (MAC) is brain isoelectric activity observed?

    <p>1.5-2</p> Signup and view all the answers

    Which of the following drugs is characterized by epileptiform activity?

    <p>Sevoflurane</p> Signup and view all the answers

    Which drug is characterized by myoclonus with no epileptiform activity?

    <p>Etomidate</p> Signup and view all the answers

    The development of new ___ waves during anesthesia maintenance indicates a risk for ischemia.

    <p>delta</p> Signup and view all the answers

    Which of the following are considered mimics for cerebral ischemia? (Select all that apply)

    <p>Deep anesthesia</p> Signup and view all the answers

    20-30 sec lag time between EEG measurement and BIS value

    <p>True</p> Signup and view all the answers

    Which of the following factors impair the accuracy of bispectral index (BIS) monitoring? (Select all that apply)

    <p>Hypothermia</p> Signup and view all the answers

    Which agents decrease bispectral index (BIS) without a sedative effect?

    <p>Neuromuscular blocking agents</p> Signup and view all the answers

    What are somatosensory evoked potentials? (select 2)

    <p>Electrical signals measured from the periphery to the brain brain in response to tactile stimuli</p> Signup and view all the answers

    What is the best anesthetic technique for SSEP monitoring?

    <p>Total Intravenous Anesthesia (TIVA)</p> Signup and view all the answers

    Which agents should be avoided in SSEP monitoring? (select 3)

    <p>Ketamine - increase</p> Signup and view all the answers

    What are the three types of sensory evoked potentials?

    <p>Somatosensory Evoked Potentials (SSEP)</p> Signup and view all the answers

    What is the preferred anesthetic when monitoring Visual Evoked Potentials (VEPs)?

    <p>TIVA</p> Signup and view all the answers

    Which sensory evoked potential is unique in its resistance to the influence of anesthetic agents?

    <p>Brainstem auditory evoked potentials</p> Signup and view all the answers

    You note a 50% decrease in amplitude during evoked potential monitoring during surgery. What is this indicative of?

    <p>Impending nerve damage</p> Signup and view all the answers

    What are the peaks and troughs of waveforms called in evoked potentials?

    <p>Polarity and latency</p> Signup and view all the answers

    A BAEP with increased latency of __ mS is a significant finding

    <p>greater than 2</p> Signup and view all the answers

    Where are MEPs recorded in response to depolarization of the motor cortex?

    <p>Over muscles in the hand</p> Signup and view all the answers

    What is the preferred anesthetic management for monitoring motor evoked potentials (MEPs)?

    <p>TIVA with no NMBDs</p> Signup and view all the answers

    What is the difference between the SEP and EEG response to inhaled anesthetics? (select 2)

    <p>SEPs are recordable with inhaled anesthetics</p> Signup and view all the answers

    What is the difference between the amplitude of waves in Somatosensory Evoked Potentials (SEPs) and Electroencephalography (EEG)?

    <p>EEG waves typically have a larger amplitude than SEP waves.</p> Signup and view all the answers

    Which cranial nerves can be monitored via EMG? (Select all that apply)

    <p>All except I, II, VIII</p> Signup and view all the answers

    What is the normal range of cerebral blood flow (CBF) in mL/100g?

    <p>50-65 mL/100g</p> Signup and view all the answers

    Match the following CBF limits (ml/100g/min) with their corresponding conditions:

    <p>50 = Acidosis 40 = Impaired protein synthesis &lt;30 = Edema &lt;20 = Critically low CBF</p> Signup and view all the answers

    Match the Cerebral Perfusion Pressure (CPP) values with their corresponding events:

    <p>30-40 = Ischemia &lt; 30 = Critical CPP &lt; 25 = Irreversible brain damage 80-100 = Normal</p> Signup and view all the answers

    What is the critical PaO2 level considered to be?

    <p>&lt;50 mmHg</p> Signup and view all the answers

    What is the critical level of paCO2 considered to be hazardous?

    <p>Less than 20 mmHg</p> Signup and view all the answers

    What factors determine cerebral blood flow (CBF)?

    <p>All of the above</p> Signup and view all the answers

    What are NIM (Nerve Integrity Monitors) ETTs used for?

    <p>Assessing nerve function during surgical procedures involving the airway</p> Signup and view all the answers

    What can EEG be used to monitor in neuroanesthesia?

    <p>Ischemia/perfusion</p> Signup and view all the answers

    What are the limitations of laser Doppler flowmetry in measuring cerebral blood flow (CBF)? select 2

    <p>It only measures local CBF.</p> Signup and view all the answers

    What are the limitations of transcranial Doppler ultrasonography? (Select all that apply)

    <p>Requires a fixation device</p> Signup and view all the answers

    What is transcranial Doppler ultrasonography used to measure?

    <p>Intracranial pressure (ICP)</p> Signup and view all the answers

    What is the primary purpose of microdialysis catheters in neuroanesthesia?

    <p>To semi-quantitatively assess vessel patency and flow in the aneurysmal sac</p> Signup and view all the answers

    What is Indocyanine green video angiography used to measure during aneurysm surgery?

    <p>Cerebral blood flow</p> Signup and view all the answers

    Where are supratentorial pressures measured?

    <p>Lateral ventricle and subarachnoid space over the convexity of the cerebral cortex</p> Signup and view all the answers

    What is the jugular bulb?

    <p>A dilated region of the internal jugular vein that collects blood from the brain with negligible contamination</p> Signup and view all the answers

    What is the purpose of jugular venous oxygen saturation?

    <p>Estimation of global balance between cerebral O2 demand and supply via the jugular bulb</p> Signup and view all the answers

    What are the limitations of jugular venous oxygen saturation measurement? select 2

    <p>It cannot detect focal cerebral ischemia.</p> Signup and view all the answers

    What is near infrared spectroscopy in the context of cerebral oximetry?

    <p>A technique to measure tissue oxygen saturation</p> Signup and view all the answers

    What are the limitations of cerebral oximetry? (Select all that apply)

    <p>Intersubject variability</p> Signup and view all the answers

    What are precordial Dopplers used to detect?

    <p>Venous air embolism</p> Signup and view all the answers

    Which of the following monitors are used to monitor intracranial pressure (ICP)? (Select all that apply)

    <p>Intraventricular catheter</p> Signup and view all the answers

    Which anesthetic is known to cause non-rapid eye movement sleep patterns on the EEG?

    <p>Dexmedetomidine</p> Signup and view all the answers

    What is characteristic of the EEG pattern of propofol?

    <p>Early beta waves progressing to synchronous alpha waves</p> Signup and view all the answers

    What is a limitation of the Bispectral Index (BIS)?

    <p>All of the above</p> Signup and view all the answers

    Which types of operations have a high potential for damaging cranial nerves? (Select all that apply)

    <p>Posterior fossa</p> Signup and view all the answers

    Study Notes

    Neuroanesthesia Goals

    • Overall Goal: Ensure brain receives sufficient oxygen and glucose
    • Perioperative Goals:
      • Maintain favorable blood and oxygen supply
      • Prevent brain herniation
      • Facilitate muscle relaxation

    Risks

    • Patients with neurological disease undergoing surgery are at higher risk of brain hypoxia and ischemia

    Intraoperative Monitoring

    • Goal: Improve patient outcomes via early detection of issues and adjusting anesthetic/surgical procedures
    • Standard Monitors: EKG, BP, SPO2, ETCO2, temperature, precordial or esophageal stethoscope
    • Expanded Monitors: Art line, CVP, PA, precordial doppler

    Categories of Neurophysiologic Monitoring

    • Function: EEG, evoked potentials, electromyography
    • Blood Flow: CBF, ICP
      • CBF Measurement Methods:
        • Nitrous oxide wash-in
        • Radioactive xenon clearance
        • Laser Doppler blood flow
      • ICP Measurement Methods:
        • Intraventricular catheter
        • Sub-arachnoid bolt
        • Epidural catheter
        • Fiberoptic parenchymal catheter
    • Metabolism:
      • Invasive: Intercerebral PO2 electrode
      • Non-invasive: Transcranial cerebral oximetry and jugular venous oximetry

    EEG

    • Definition: Recording of brain's electrical activity from the cerebral cortex
    • Source: Pyramidal cells in the cerebral cortex
      • Result of summation of excitatory and inhibitory postsynaptic potentials
    • Primarily records cortical activity: Limited recording of subcortical structures, spinal cord, cranial nerves, and peripheral nerves
    • Oxygen and Glucose Dependency: EEG is significantly impacted by oxygen and glucose supply
    • Monitoring Locations:
      • Scalp: Electrically neutral area
        • Electrodes can be taped or use small needles
      • International 10-20 System: Standardized electrode placement
        • 10 or 20% of skull circumference between electrodes
        • Even numbers: Right Hemisphere
        • Odd numbers: Left Hemisphere
        • Landmarks:
          • Nasion: Depressed area between eyes
          • Inion: Lowest point of the skull
    • EEG Wave Patterns:
      • Beta waves: High frequency, low amplitude (awake)
      • Alpha waves: Medium frequency, higher amplitude (awake and relaxed)
      • Theta waves: Low frequency (children during sleep)
      • Delta waves: Low frequency, high amplitude (deep coma, anesthesia, hypoxia)
    • EEG Reflects: Brain wakefulness and metabolic activity
    • EEG Depression Causes
      • Decreased blood flow
      • Reduced oxygen supply
      • Insufficient glucose
    • Awake EEG: Dominated by high frequency, low amplitude beta waves
    • Hypoxia/Ischemia EEG Changes:
      • Initial increase in beta activity (compensation mechanism)
      • Slow theta waves
      • Disappearance of beta waves
      • Low amplitude delta waves

    Abnormal EEG Patterns

    • Generalized slowing: Slowed activity
    • Focal or localized slow activity: Slow activity in a specific area
    • Periodic patterns: Recurring patterns

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    Description

    This quiz covers the key goals and monitoring strategies in neuroanesthesia, focusing on maintaining brain function during surgery. It addresses risks associated with neurological diseases, intraoperative monitoring techniques, and methods for measuring cerebral blood flow and intracranial pressure.

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