Neuro Oncology: CNS Tumors and Lesions
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Neuro Oncology: CNS Tumors and Lesions

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Questions and Answers

What is the characteristic feature of Medulloblastoma?

  • Pseudopallisading cells
  • Rosenthal fibers
  • Homer-Wright rosettes (correct)
  • Psamoma bodies
  • Which tumor is associated with estrogen receptor and psamoma bodies?

  • Meningioma (correct)
  • Pilocytic Astrocytoma
  • Ependymoma
  • Oligodendroglioma
  • What is the typical location of Pilocytic Astrocytoma?

  • Frontal lobe
  • Cerebellum (correct)
  • Cerebral hemisphere
  • 4th ventricle
  • What is the characteristic feature of Glioblastoma Multiforme?

    <p>Pseudopallisading cells</p> Signup and view all the answers

    What is the typical location of Ependymoma?

    <p>4th ventricle</p> Signup and view all the answers

    Study Notes

    CNS Tumors Below the Tentorium

    • Tumors originate from different types of glial and neuronal cells, commonly affecting children and adults.

    Key Tumors in Children

    • Pilocytic Astrocytoma:

      • Benign tumor arising in the cerebellum.
      • Characterized by Rosenthal fibers and GFAP positivity.
    • Ependymoma:

      • Malignant tumor typically located in the fourth ventricle.
      • Associated with complications like hydrocephalus and pseudorosettes.
    • Medulloblastoma:

      • Highly malignant tumor arising from neuroectodermal tissues in the cerebellum.
      • Identified by small round blue cells and Homer-Wright rosettes.

    Key Tumors in Adults

    • Glioblastoma Multiforme:

      • Malignant, located in the cerebral hemispheres; crosses midline creating a "butterfly" appearance.
      • Features pseudopallisading necrosis and is GFAP positive.
    • Oligodendroglioma:

      • Malignant, often found in calcified frontal lobe white matter.
      • Characterized by seizures and "fried egg" appearance of cells.
    • Meningioma:

      • Generally benign, arises from arachnoid cells.
      • Appears as a round mass attached to the dura mater, can be associated with seizures and contain psammoma bodies.
    • Schwannoma:

      • Benign tumor of the 8th cranial nerve, located at the cerebellopontine angle.
      • Characterized by S100 positivity, often associated with neurofibromatosis type 2 (NF2).

    Additional Tumors

    • Ependymoma:

      • Can occur in children or adults, typically in the fourth ventricle, leading to hydrocephalus.
    • Craniopharyngioma:

      • Arises from Rathke's pouch near the optic chiasm, can cause bitemporal hemianopsia.

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    Test your knowledge of Central Nervous System tumors and lesions, including astrocytomas, oligodendrogliomas, meningiomas, and more. Learn to identify and differentiate between various types of CNS tumors and lesions.

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