Neural Tube Formation Process Quiz
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Questions and Answers

Which protein provides instructions for making Sonic Hedgehog, functioning as a chemical signal essential for embryonic development?

  • Smoothened
  • Shh (correct)
  • Patched
  • Gli proteins
  • In the absence of Shh, what prevents the activation of Smoothened in the neurulation process?

  • Patched (correct)
  • Hypothalamus
  • Notochord
  • Gli proteins
  • During zebrafish development, where is the mesoderm of the head first specified?

  • On the ventral side of the embryo
  • Near the animal pole
  • On the dorsal side of the embryo (correct)
  • At the equator
  • What is the role of Gli proteins in the hedgehog signaling pathway during embryogenesis?

    <p>Repress gene transcription</p> Signup and view all the answers

    What is the main role of Shh secreted from the notochord in neural tube development?

    <p>Dorsoventral patterning</p> Signup and view all the answers

    Which structure plays a key role in initiating neurulation by influencing the formation of the neural plate under the influence of Shh?

    <p>Notochord</p> Signup and view all the answers

    Which phase of AP patterning in vertebrate embryos involves the formation of muscle tissue blocks called somites?

    <p>Elaboration phase</p> Signup and view all the answers

    What happens when Shh binds to Patched-1 during the hedgehog signaling pathway?

    <p>Inhibits Smoothened activation</p> Signup and view all the answers

    At what stage in zebrafish development does the initiation phase occur?

    <p>Before gastrulation</p> Signup and view all the answers

    Which gene is an obligate negative regulator in shh signaling and plays an essential role in embryogenesis?

    <p>Patched</p> Signup and view all the answers

    Which stage involves the migration of cells towards the animal pole to form the brain during zebrafish development?

    <p>Gastrulation</p> Signup and view all the answers

    What is the central role played by the mesoderm of the head during zebrafish development?

    <p>Specification of the organizer</p> Signup and view all the answers

    During neural tube formation, what is the process where the neural plate creases inward until the edges come in contact and fuse?

    <p>Primary neurulation</p> Signup and view all the answers

    Which part of the neural tube gives rise to the brain and spinal cord in the central nervous system?

    <p>Internally located neural tube</p> Signup and view all the answers

    What is the result of the neural fold pinching inside towards the middle line of the embryo and fusing together during primary neurulation?

    <p>Formation of the neural tube</p> Signup and view all the answers

    Which part of the neural tube forms a cord-like structure that migrates inside the embryo during secondary neurulation?

    <p>Neural plate</p> Signup and view all the answers

    Which signaling molecule controls the development of the spinal cord within the CNS?

    <p>Sonic hedgehog (Shh)</p> Signup and view all the answers

    What does the anterior part of the neural tube develop into during early brain development?

    <p>Forebrain</p> Signup and view all the answers

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