Neural Tube Formation Process Quiz

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Which protein provides instructions for making Sonic Hedgehog, functioning as a chemical signal essential for embryonic development?

Smoothened

Shh (correct)

Patched

Gli proteins

In the absence of Shh, what prevents the activation of Smoothened in the neurulation process?

Patched (correct)

Hypothalamus

Notochord

Gli proteins

During zebrafish development, where is the mesoderm of the head first specified?

On the ventral side of the embryo

Near the animal pole

On the dorsal side of the embryo (correct)

At the equator

What is the role of Gli proteins in the hedgehog signaling pathway during embryogenesis?

Repress gene transcription Signup and view all the answers

What is the main role of Shh secreted from the notochord in neural tube development?

Dorsoventral patterning Signup and view all the answers

Which structure plays a key role in initiating neurulation by influencing the formation of the neural plate under the influence of Shh?

Notochord Signup and view all the answers

Which phase of AP patterning in vertebrate embryos involves the formation of muscle tissue blocks called somites?

Elaboration phase Signup and view all the answers

What happens when Shh binds to Patched-1 during the hedgehog signaling pathway?

Inhibits Smoothened activation Signup and view all the answers

At what stage in zebrafish development does the initiation phase occur?

Before gastrulation Signup and view all the answers

Which gene is an obligate negative regulator in shh signaling and plays an essential role in embryogenesis?

Patched Signup and view all the answers

Which stage involves the migration of cells towards the animal pole to form the brain during zebrafish development?

Gastrulation Signup and view all the answers

What is the central role played by the mesoderm of the head during zebrafish development?

Specification of the organizer Signup and view all the answers

During neural tube formation, what is the process where the neural plate creases inward until the edges come in contact and fuse?

Primary neurulation Signup and view all the answers

Which part of the neural tube gives rise to the brain and spinal cord in the central nervous system?

Internally located neural tube Signup and view all the answers

What is the result of the neural fold pinching inside towards the middle line of the embryo and fusing together during primary neurulation?

Formation of the neural tube Signup and view all the answers

Which part of the neural tube forms a cord-like structure that migrates inside the embryo during secondary neurulation?

Neural plate Signup and view all the answers

Which signaling molecule controls the development of the spinal cord within the CNS?

Sonic hedgehog (Shh) Signup and view all the answers

What does the anterior part of the neural tube develop into during early brain development?

Forebrain Signup and view all the answers