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What are the two main divisions of the nervous system?
What are the two main divisions of the nervous system?
Central Nervous System and Peripheral Nervous System
What is the basic functional unit of the brain?
What is the basic functional unit of the brain?
What are the functions of the nervous system?
What are the functions of the nervous system?
Control all motor, sensory, autonomic, cognitive, and behavioral activities
What is the function of dendrites in a neuron?
What is the function of dendrites in a neuron?
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What does the axon in a neuron do?
What does the axon in a neuron do?
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What are ganglia or nuclei?
What are ganglia or nuclei?
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What is a center in the nervous system?
What is a center in the nervous system?
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What is the function of neuroglial cells?
What is the function of neuroglial cells?
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What is the function of neurotransmitters?
What is the function of neurotransmitters?
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What are the two types of neurotransmitter receptors?
What are the two types of neurotransmitter receptors?
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Which neurotransmitter is associated with the “fight-or-flight” response?
Which neurotransmitter is associated with the “fight-or-flight” response?
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What are the three major parts of the brain?
What are the three major parts of the brain?
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What is the largest part of the brain?
What is the largest part of the brain?
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Which part of the brain controls voluntary movement?
Which part of the brain controls voluntary movement?
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What is the function of the cerebellum?
What is the function of the cerebellum?
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Which part of the brain controls heart rate, respiration, and blood pressure?
Which part of the brain controls heart rate, respiration, and blood pressure?
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What is the function of the pons?
What is the function of the pons?
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What are the meninges?
What are the meninges?
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What is the outermost layer of the meninges?
What is the outermost layer of the meninges?
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What is the middle layer of the meninges?
What is the middle layer of the meninges?
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What is cerebrospinal fluid?
What is cerebrospinal fluid?
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Where is cerebrospinal fluid produced?
Where is cerebrospinal fluid produced?
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What is the primary function of the choroid plexus?
What is the primary function of the choroid plexus?
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What is the function of the blood-brain barrier?
What is the function of the blood-brain barrier?
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The blood-brain barrier is a permeable barrier that allows all substances to pass through.
The blood-brain barrier is a permeable barrier that allows all substances to pass through.
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What are the two main functions of the spinal cord?
What are the two main functions of the spinal cord?
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What are ascending tracts in the spinal cord?
What are ascending tracts in the spinal cord?
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What is the function of the vertebral column?
What is the function of the vertebral column?
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What are the two main divisions of the peripheral nervous system?
What are the two main divisions of the peripheral nervous system?
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What is the function of the somatic nervous system?
What is the function of the somatic nervous system?
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What is the function of the autonomic nervous system?
What is the function of the autonomic nervous system?
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Which branch of the autonomic nervous system is responsible for the “fight-or-flight” response?
Which branch of the autonomic nervous system is responsible for the “fight-or-flight” response?
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Which branch of the autonomic nervous system is responsible for the “rest-and-digest” response?
Which branch of the autonomic nervous system is responsible for the “rest-and-digest” response?
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What is the function of the motor cortex?
What is the function of the motor cortex?
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The motor system is composed of only one neuron pathway.
The motor system is composed of only one neuron pathway.
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Which of the following is NOT a characteristic of lower motor neuron lesions?
Which of the following is NOT a characteristic of lower motor neuron lesions?
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What is the primary function of the cerebellum?
What is the primary function of the cerebellum?
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What is the function of the basal ganglia?
What is the function of the basal ganglia?
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What is a common neurological disorder caused by dysfunction of the basal ganglia?
What is a common neurological disorder caused by dysfunction of the basal ganglia?
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What is the function of the thalamus?
What is the function of the thalamus?
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What part of the brain receives sensory signals?
What part of the brain receives sensory signals?
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What are the three main types of diagnostic exams used to assess neurological function?
What are the three main types of diagnostic exams used to assess neurological function?
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What is the function of computed tomography (CT) scanning in neurology?
What is the function of computed tomography (CT) scanning in neurology?
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What is the function of magnetic resonance imaging (MRI) in neurology?
What is the function of magnetic resonance imaging (MRI) in neurology?
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What is the function of electroencephalography (EEG) in neurology?
What is the function of electroencephalography (EEG) in neurology?
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What are the main clinical manifestations of neurological conditions?
What are the main clinical manifestations of neurological conditions?
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What is the medical term for a stroke?
What is the medical term for a stroke?
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What are two major types of strokes?
What are two major types of strokes?
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Ischemic strokes are more common than hemorrhagic strokes.
Ischemic strokes are more common than hemorrhagic strokes.
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Flashcards
Central Nervous System
Central Nervous System
One of the two main divisions of the nervous system. It includes the brain and spinal cord.
Peripheral Nervous System
Peripheral Nervous System
The other main division of the nervous system, comprising all nerves branching out from the CNS.
Neuron
Neuron
The basic functional unit of the nervous system. It has dendrites and an axon.
Dendrite
Dendrite
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Axon
Axon
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Ganglia/Nuclei
Ganglia/Nuclei
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Neuroglial Cells
Neuroglial Cells
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Neurotransmitters
Neurotransmitters
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Direct Receptors
Direct Receptors
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Indirect Receptors
Indirect Receptors
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Cerebrum
Cerebrum
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Cerebellum
Cerebellum
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Brain Stem
Brain Stem
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Cerebrovascular Accident (CVA)
Cerebrovascular Accident (CVA)
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Ischemic Stroke
Ischemic Stroke
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Hemorrhagic Stroke
Hemorrhagic Stroke
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Spinal Cord
Spinal Cord
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Meninges
Meninges
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Cerebrospinal Fluid (CSF)
Cerebrospinal Fluid (CSF)
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Blood-Brain Barrier
Blood-Brain Barrier
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Cranial Nerves
Cranial Nerves
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Spinal Nerves
Spinal Nerves
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Somatic Nervous System
Somatic Nervous System
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Autonomic Nervous System
Autonomic Nervous System
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What is the purpose of the Nervous System?
What is the purpose of the Nervous System?
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What are neurons?
What are neurons?
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What do dendrites do?
What do dendrites do?
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What does an axon do?
What does an axon do?
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What are ganglia or nuclei?
What are ganglia or nuclei?
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What are neuroglial cells?
What are neuroglial cells?
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What are neurotransmitters?
What are neurotransmitters?
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What are direct receptors?
What are direct receptors?
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What are indirect receptors?
What are indirect receptors?
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What are the three main parts of the brain?
What are the three main parts of the brain?
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What is the cerebrum responsible for?
What is the cerebrum responsible for?
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What is the cerebellum responsible for?
What is the cerebellum responsible for?
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What is the brainstem responsible for?
What is the brainstem responsible for?
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What are the meninges?
What are the meninges?
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What is cerebrospinal fluid (CSF)?
What is cerebrospinal fluid (CSF)?
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What is the blood-brain barrier?
What is the blood-brain barrier?
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What are cranial nerves?
What are cranial nerves?
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What are spinal nerves?
What are spinal nerves?
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What is the somatic nervous system?
What is the somatic nervous system?
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What is the autonomic nervous system?
What is the autonomic nervous system?
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What is the sympathetic nervous system?
What is the sympathetic nervous system?
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What is the parasympathetic nervous system?
What is the parasympathetic nervous system?
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How does the motor cortex control movement?
How does the motor cortex control movement?
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What is the difference between upper and lower motor neurons?
What is the difference between upper and lower motor neurons?
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What is the cerebellum's role in coordination of movement?
What is the cerebellum's role in coordination of movement?
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What is the basal ganglia's role in coordination of movement?
What is the basal ganglia's role in coordination of movement?
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What is the function of the sensory system?
What is the function of the sensory system?
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What are some examples of sensory losses?
What are some examples of sensory losses?
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What is a computed tomography (CT) scan?
What is a computed tomography (CT) scan?
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What is a positron emission tomography (PET) scan?
What is a positron emission tomography (PET) scan?
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What is a magnetic resonance imaging (MRI) scan?
What is a magnetic resonance imaging (MRI) scan?
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Study Notes
Nervous System Overview
- The nervous system has two main divisions: Central Nervous System (CNS) and Peripheral Nervous System (PNS).
- The CNS and PNS work together to control all motor, sensory, autonomic, cognitive, and behavioral activities.
Cells of the Nervous System
- Neuron: The basic functional unit of the brain, composed of dendrites and an axon.
- Dendrite: A branch-like structure that receives signals (receiving).
- Axon: A long projection that sends signals (sending).
- Ganglia or Nuclei: Clusters of nerve cell bodies that share a common function.
- Neuroglial Cells: Support, protect, and nourish neurons.
Neurotransmitters
- Neurotransmitters carry messages from one neuron to another or to a specific tissue.
- They can excite or inhibit the target cell's activity.
- They play crucial roles in neurologic functions and disorders.
- Types of Neurotransmitter Receptors:
- Direct (inotropic): Linked to ion channels, allowing rapid action.
- Indirect (metabotropic): Affect metabolic processes; slower acting.
- Examples of Neurotransmitters:
- Acetylcholine (parasympathetic)>
- Serotonin
- Dopamine
- Norepinephrine (sympathetic)
- GABA
- Enkephalin, endorphin
Central Nervous System (CNS)
-
Brain:
- Cerebrum: Divided into hemispheres (Left and Right); includes the cerebral cortex, with areas for specific functions like language, sensory perception, and movement; subcortical structures (corpus callosum, basal ganglia, thalamus, hypothalamus).
- Cerebellum: Crucial for coordination of movement, balance, and fine motor skills.
- Brain Stem: Connects the brain and spinal cord; includes the midbrain, pons, and medulla oblongata.
-
Spinal Cord:
- Connects the brain and the periphery (responsible for voluntary skeletal muscle movements).
- Contains gray matter (center) and white matter (surrounding).
Parts of the Brain (Detailed)
- Cerebrum: Two hemispheres (L&R), composed of:
- Gyri: Folds
- Sulci: Grooves
- Fissures: Deep grooves
- These structures divide the cerebrum into lobes (frontal, parietal, temporal, occipital) containing further-defined areas for specific functions like motor control, sensory processing, and memory.
- Corpus Callosum: Connects the two hemispheres, allowing information transfer.
- Basal Ganglia: Clusters of nuclei involved in motor control and posture.
- Thalamus: Relay center for sensory information (except smell); involved in memory and pain impulses.
- Hypothalamus: Crucial for regulating endocrine system, fluid balance, temperature, hunger, sleep-wake cycle, and emotional responses.
- Pituitary Gland: Common site for brain tumors; plays a significant role in hormonal balance.
- Midbrain: Connects pons and cerebellum to cerebral hemispheres, handles sensory and motor pathways, and controls auditory/visual reflexes. Also, the origin point of Cranial Nerves III and IV.
- Pons: Cranial nerves V-VIII connect to the brain, handles motor and sensory pathways, and controls heart, respiration, and blood pressure.
Cerebrospinal Fluid (CSF)
- Clear fluid with a very specific gravity; circulates around the brain and spinal cord.
- Produced in the ventricles and circulates throughout the subarachnoid space.
- Absorbed by arachnoid villi.
- Similar in composition to blood plasma; minimal WBC with no RBC present.
Arteries (Cerebral Circulation)
- Two internal carotid arteries and two vertebral arteries supply blood to the brain.
- Internal carotid arteries supply the anterior brain.
- Basilar artery supplies posterior brain.
- Circle of Willis connects these arteries to provide a collateral circulation, ensuring flow if one of the main vessels is blocked.
Veins
- Carry venous blood out of the brain and into the internal jugular vein.
- Do not have valves; rely on gravity and blood pressure.
Blood-Brain Barrier
- Barrier to certain substances entering the brain.
- Substances like macromolecules and many compounds must pass through endothelial cells and astrocytes.
Spinal Cord
- Connects the brain and periphery, contains gray mater and white mater; surrounded by meninges.
Sensory and Motor Pathways
- White matter in the spinal cord is composed of myelinated and unmyelinated nerve fibers.
- Fiber bundles having a similar function form tracts.
- Six ascending tracts and eight descending tracts exist within the spinal cord that carry signals in opposite directions.
Vertebral Column
- The vertebral column encases and protects the spinal cord.
- It's composed of vertebrae (cervical, thoracic, lumbar, sacrum, coccyx), separated by intervertebral disks.
- Nerve roots exit the spinal cord through foramina.
Peripheral Nervous System (PNS)
- All nerves outside the brain and spinal cord.
- Includes cranial nerves (I-XII), spinal nerves, autonomic (involuntary) nervous system, and somatic (voluntary) nervous system.
- Cranial and Spinal nerves.
Autonomic Nervous System (ANS)
- Controls involuntary functions; maintain homeostasis.
- Has two divisions: sympathetic ("fight-or-flight") and parasympathetic ("rest-or-digest").
Motor System Function
Motor cortex controls voluntary body movements via a two-neuron pathway.
Upper and Lower Motor Neurons
- Upper Neuron: Originates in cerebral cortex, cerebellum, or brainstem.
- Lower Neuron: Located in spinal cord (anterior horn), or cranial nerve nuclei in brainstem, controls final signals to muscles.
- Comparison of Upper vs Lower Neuron Lesions: provides a table describing changes in muscle tone, presence or absence of atrophy and reflexes
Coordination of Movement
- Cerebellum coordinates voluntary movements, balance, and timing.
- Basal ganglia aid in planning and coordinating motor movements and posture.
- Impaired function can result in abnormal posturing (decorticate, decerebrate, flaccid).
- Diseases that affect basal ganglia include Parkinson's disease, Huntington's disease, and spasmodic torticollis.
Sensory System Function
- Conscious awareness of pain, temperature, touch; sense of movement and position; ability to recognize size, shape, and quality of object.
- Sensory input is received, integrated, and processed to generate a sensory experience.
- Sensory losses could occur due to damage to posterior columns, spinal cord, or nerve roots.
Assessment: Neurological Examination
- History: Onset, symptoms, location, duration, medical, and family history including genetic factors.
- Clinical Manifestations: Symptoms such as pain, seizures, dizziness, visual disturbances, weakness, and abnormal sensation.
- Physical Examination: assess mental status, intellectual function, thought content, emotional status, and perception (including muscle size, strength, tone, coordination, reflexes; and sensory function including pain, touch, temperature).
- Cranial Nerves: Assessment of each nerve function using specific testing methods.
- Motor System: Evaluation for muscle size, strength, tone, coordination, and balance. Use specific tests to grade ability to move against resistance; test muscle strength.
- Reflexes: Testing of specific involuntary reflexes (e.g., biceps, triceps, brachioradialis, Babinski, patellar, ankle reflexes, superficial reflexes).
Diagnostic Evaluations
- Computed Tomography Scan (CT Scan): Uses x-rays to create cross-sectional images of the brain and surrounding structures to detect abnormalities like tumors.
- Positron Emission Tomography (PET Scan): Measures organ function by tracking radioactive substances in the body; helpful in assessing metabolic activity in brain regions
- Single Photon Emission Computed Tomography (SPECT): Measures blood flow or perfusion in the brain and detects abnormalities or areas with decreased blood flow
- Magnetic Resonance Imaging (MRI): Creates detailed images of the brain's structures and detects chemical changes within cells.
- Cerebral Angiography: X-ray of cerebral circulation, allowing visualization of blood vessels and detects abnormalities.
- Noninvasive Carotid Flow Studies: Uses ultrasound and Doppler to measure blood flow velocity in the carotid arteries.
- Myelography: X-ray of the spinal canal after contrast agent injection, assesses the spinal cord and its surroundings for lesions.
- Transcranial Doppler: Measures blood flow velocities (similar methods to carotid doppler).
- Electroencephalography (EEG): Measures electrical activity in the brain, used to diagnose seizures, coma, and brain syndromes.
- Electromyography (EMG): Measures electrical activity in skeletal muscles; assesses muscles/nerves.
- Nerve Conduction Studies: Evaluates nerve function by stimulating nerves and measuring electrical signals; assesses peripheral nerve function.
- Lumbar Puncture: Sampling of CSF; helps in assessing certain conditions. Use Queckenstedt's test to assess CSF pressure and flow.
Gerontological Considerations
- Age-related structural changes affecting the brain and nervous system.
- Possible sensory and motor alterations.
- Changes in pain and temperature perception, taste, and smell.
- Changes in cognitive function and mental status.
Acute Neurological Conditions
- Cerebrovascular Accident (CVA): Also known as a stroke, caused by blockage or rupture of blood vessels in the brain. Ischemic and hemorrhagic types exist.
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Description
Test your knowledge on the structure and function of the nervous system, including its main divisions, cells, and neurotransmitters. This quiz covers essential concepts that are critical for understanding how the nervous system operates and its role in human physiology.