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Questions and Answers
Which of the following is NOT a function of the myelin sheath?
Which of the following is NOT a function of the myelin sheath?
Myelinated fibers conduct nerve impulses more slowly than non-myelinated fibers.
Myelinated fibers conduct nerve impulses more slowly than non-myelinated fibers.
False (B)
What type of glial cell is responsible for forming the myelin sheath in the peripheral nervous system (PNS)?
What type of glial cell is responsible for forming the myelin sheath in the peripheral nervous system (PNS)?
Schwann cells
In the CNS, the myelin sheath is formed by ______, while in the PNS, it is formed by ______.
In the CNS, the myelin sheath is formed by ______, while in the PNS, it is formed by ______.
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Match the following terms related to the myelin sheath with their corresponding descriptions:
Match the following terms related to the myelin sheath with their corresponding descriptions:
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Which of the following is NOT a function of astrocytes?
Which of the following is NOT a function of astrocytes?
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Neuroglia are the main cells responsible for transmitting electrical signals in the nervous system.
Neuroglia are the main cells responsible for transmitting electrical signals in the nervous system.
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What are the three functional zones of a neuron and their roles?
What are the three functional zones of a neuron and their roles?
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The ____ are the most abundant type of neuroglia in the CNS.
The ____ are the most abundant type of neuroglia in the CNS.
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Match the following neuroglia with their primary function:
Match the following neuroglia with their primary function:
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Which of the following statements accurately describes the differences between a nerve and a tract?
Which of the following statements accurately describes the differences between a nerve and a tract?
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Ependymal cells are responsible for forming the blood-brain barrier.
Ependymal cells are responsible for forming the blood-brain barrier.
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What is the difference between a nucleus and a ganglion?
What is the difference between a nucleus and a ganglion?
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What is the primary function of excitatory neurotransmitters at the synapse?
What is the primary function of excitatory neurotransmitters at the synapse?
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The same neurotransmitter is always released at a specific synapse.
The same neurotransmitter is always released at a specific synapse.
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What are the two main inhibitory neurotransmitters, and what effect do they have on the postsynaptic membrane?
What are the two main inhibitory neurotransmitters, and what effect do they have on the postsynaptic membrane?
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The most common neurotransmitter in the peripheral nervous system (PNS) is ______.
The most common neurotransmitter in the peripheral nervous system (PNS) is ______.
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Match the neurotransmitter with its primary effect at the synapse:
Match the neurotransmitter with its primary effect at the synapse:
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The resting membrane potential (RMP) is always positive on the inside of the cell.
The resting membrane potential (RMP) is always positive on the inside of the cell.
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The sodium-potassium pump actively transports ______ sodium ions out of the cell for every ______ potassium ions pumped into the cell.
The sodium-potassium pump actively transports ______ sodium ions out of the cell for every ______ potassium ions pumped into the cell.
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Which of the following is NOT a characteristic of graded potentials?
Which of the following is NOT a characteristic of graded potentials?
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Match each type of potential with its correct description:
Match each type of potential with its correct description:
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What are the four steps involved in the generation of an action potential? Briefly describe each step.
What are the four steps involved in the generation of an action potential? Briefly describe each step.
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What is the threshold of an action potential?
What is the threshold of an action potential?
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Explain how action potentials are propagated along neurons.
Explain how action potentials are propagated along neurons.
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EPSPs are depolarizing events that make it more likely for a neuron to fire an action potential.
EPSPs are depolarizing events that make it more likely for a neuron to fire an action potential.
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What is the function of an excitatory postsynaptic potential (EPSP)?
What is the function of an excitatory postsynaptic potential (EPSP)?
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The combined effect of multiple simultaneous inputs from different synapses is called ______.
The combined effect of multiple simultaneous inputs from different synapses is called ______.
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A single EPSP is always sufficient to trigger an action potential in the postsynaptic neuron.
A single EPSP is always sufficient to trigger an action potential in the postsynaptic neuron.
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Explain the difference between excitatory and inhibitory postsynaptic potentials.
Explain the difference between excitatory and inhibitory postsynaptic potentials.
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Match the following terms with their corresponding descriptions:
Match the following terms with their corresponding descriptions:
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What does it mean for behavior to occur when neurons are released from inhibition?
What does it mean for behavior to occur when neurons are released from inhibition?
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IPSPs make the postsynaptic membrane more permeable to potassium (K+) and chloride (Cl-) ions.
IPSPs make the postsynaptic membrane more permeable to potassium (K+) and chloride (Cl-) ions.
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The combined effect of repeated inputs from the same synapse is called ______.
The combined effect of repeated inputs from the same synapse is called ______.
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What triggers the release of acetylcholine (ACh) in the excitatory cholinergic effect?
What triggers the release of acetylcholine (ACh) in the excitatory cholinergic effect?
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The excitatory adrenergic effect involves direct action through voltage-gated channels.
The excitatory adrenergic effect involves direct action through voltage-gated channels.
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What is the result of GABA binding to its receptors in the postsynaptic neuron?
What is the result of GABA binding to its receptors in the postsynaptic neuron?
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In the excitatory adrenergic effect, cAMP is produced by the conversion of ATP to _____ by adenylate cyclase.
In the excitatory adrenergic effect, cAMP is produced by the conversion of ATP to _____ by adenylate cyclase.
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Match the neurotransmitter with its effect:
Match the neurotransmitter with its effect:
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Flashcards
Neuroglia
Neuroglia
Support cells in the nervous system that surround neurons.
Astrocytes
Astrocytes
Most abundant neuroglia that supports and braces neurons.
Microglial cells
Microglial cells
Small cells that monitor neurons and clean up debris.
Ependymal Cells
Ependymal Cells
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Oligodendrocytes
Oligodendrocytes
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Schwann cells
Schwann cells
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Neuron
Neuron
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Nerve vs Tract
Nerve vs Tract
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Neurotransmitter
Neurotransmitter
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Excitatory neurotransmitters
Excitatory neurotransmitters
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Inhibitory neurotransmitters
Inhibitory neurotransmitters
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Direct action of neurotransmitter
Direct action of neurotransmitter
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Indirect action of neurotransmitter
Indirect action of neurotransmitter
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Excitatory Cholinergic Effect
Excitatory Cholinergic Effect
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Calcium Channels Role
Calcium Channels Role
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Excitatory Adrenergic Effect
Excitatory Adrenergic Effect
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GABA-ergic Effect
GABA-ergic Effect
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Neuronal Integration Basics
Neuronal Integration Basics
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Synapse
Synapse
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Chemical Synapse
Chemical Synapse
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Excitatory Postsynaptic Potential (EPSP)
Excitatory Postsynaptic Potential (EPSP)
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Inhibitory Postsynaptic Potential (IPSP)
Inhibitory Postsynaptic Potential (IPSP)
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Summation
Summation
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Spatial Summation
Spatial Summation
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Temporal Summation
Temporal Summation
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Behavior and Neuron Interaction
Behavior and Neuron Interaction
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Resting Membrane Potential (RMP)
Resting Membrane Potential (RMP)
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Ion flow
Ion flow
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K+/Na+ permeability
K+/Na+ permeability
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Na/K pump
Na/K pump
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Graded Potential
Graded Potential
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EPSP
EPSP
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IPSP
IPSP
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Action Potential (AP)
Action Potential (AP)
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Myelin Sheath
Myelin Sheath
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CNS Myelin Formation
CNS Myelin Formation
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PNS Myelin Formation
PNS Myelin Formation
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Resting Membrane Potential
Resting Membrane Potential
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Myelinated vs Nonmyelinated Fibers
Myelinated vs Nonmyelinated Fibers
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Study Notes
Nervous System Overview
- The nervous system is the master controlling and communicating system of the body
- Its cells communicate via electrical and chemical signals, enabling rapid and specific responses
- Sensory receptors detect stimuli, transmitting sensory input along afferent pathways
- Integration—processing and interpreting sensory input and deciding on an appropriate response—happens in a control center.
- Motor output, via efferent pathways, triggers a reaction in effectors (muscles or glands)
Nervous System Divisions
- Central Nervous System (CNS): consisting of the brain and spinal cord
- Peripheral Nervous System (PNS): consisting of cranial nerves and spinal nerves
Nervous Tissue
- Highly cellular, with little extracellular space
- Two major cell types:
- Neuroglia: Supporting cells that surround and wrap delicate neurons
- Neurons: Excitable nerve cells that transmit electrical signals (structural and functional units of the nervous system)
Neuron Anatomy
- Has a cell body (soma) and processes (dendrites and axons)
- Three Functional Zones
- Receptive (dendritic zone): Receives input
- Conduct excitation (axon): Conducts the excitation. Initiates in initial segment
- Secretory/Transmission zone (telodendritic zone): Transmits output
Myelin Sheath
- Composed of Schwann cells in the PNS and oligodendrocytes in the CNS
- Insulates axons, increasing speed of nerve impulse transmission
Nerve and Tract Difference
- Nerve: A bundle of axons in the PNS
- Tract: Bundle of axons in the CNS
Membrane Potentials
- Resting Membrane Potential (RMP): The voltage across the plasma membrane of a resting neuron, typically ranging from -50 to -90 mV
- RMP is generated by differences in ion concentrations (inside vs. outside) and membrane permeability.
Graded Potentials
- Short-lived, local changes in membrane potential
- Strength decreases with distance
- Can be depolarizing (EPSP) or hyperpolarizing (IPSP)
- They can summate (add together) to reach a threshold
Action Potentials (AP)
- Brief, large depolarization events
- "All-or-none" phenomenon
- Generated by voltage-gated ion channels, resulting in rapid and specific movement of ions
- They propagate along axons and are essential for long-distance communication.
- Contain 4 phases, and steps to an Action Potential (depolarization, repolarization, hyperpolarization)
- Threshold: membrane depolarization must reach a certain voltage to initiate an AP
- Activation Gate: voltage-gated Na+ channels open (depolarization)
- Inactivation Gate: voltage-gated Na+ channels close, K+ channels open. (Repolarization)
Refractory Periods
- Absolute Refractory Period: A period after an AP where no new AP can be elicited, no matter the size of the stimulus
- Relative Refractory Period: A period after the absolute refractory period where a new AP can be elicited, but it will require a larger stimulus than normal
Conduction Velocity Factors
- Larger diameter axons
- Presence of myelin
Saltatory Conduction
- APs jump between myelinated sections (nodes of Ranvier) along the axon, increasing the speed of conduction
Synapses
- Junctions between neurons or between a neuron and another cell type (e.g., muscle)
- Chemical Synapse: Neurotransmitters transmit the signal across the synaptic cleft; most common
Synaptic Transmission Steps
- Action potential arrives at the axon terminal
- Voltage-gated Ca2+ channels open, Ca2+ enters
- Neurotransmitter is released via exocytosis
- Neurotransmitter binds to receptors on the postsynaptic membrane
- Response in the postsynaptic cell (either excitation or Inhibition)
- Neurotransmitter removal
Synaptic Potentials
- EPSPs (Excitatory): Graded depolarizations that increase the likelihood of an AP
- IPSPs (Inhibitory): Graded hyperpolarizations that decrease the likelihood of an AP
Synaptic Summation
- Spatial Summation: Combined effect of multiple simultaneous inputs from different synapses
- Temporal Summation: Combined effect of repeated inputs from the same synapse
Neuron Classification
- Grouped by number of processes (multipolar, bipolar, unipolar).
- Classified by functions (sensory, motor, interneurons)
Neurotransmitters and Receptors
- Chemical messengers that transmit signals across synapses
- Classes include excitatory (e.g., acetylcholine, glutamate) and inhibitory (e.g., GABA, glycine)
- Action at Specific receptors
Neural Integration
- Common patterns of neuronal organization, including diverging, converging, reverberating, and parallel after-discharge circuits.
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Description
Explore the intricate functioning of the nervous system in this quiz. Learn about its divisions, including the Central and Peripheral Nervous Systems, and the essential role of nervous tissue. Test your knowledge on how neurons and neuroglia contribute to the communication within the body.