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Questions and Answers
What stimulates the release of TSH?
What stimulates the release of TSH?
Where is the thyroid gland located?
Where is the thyroid gland located?
What is the function of glucagon?
What is the function of glucagon?
Which hormone stimulates the secretion of pancreatic juices rich in HCO3-?
Which hormone stimulates the secretion of pancreatic juices rich in HCO3-?
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Which hormone inhibits the release of GH and TSH?
Which hormone inhibits the release of GH and TSH?
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What does the thymus secrete?
What does the thymus secrete?
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What triggers the secretion of glucagon?
What triggers the secretion of glucagon?
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What is the role of parathyroid hormone (PTH)?
What is the role of parathyroid hormone (PTH)?
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Where do endocrine glands secrete their contents?
Where do endocrine glands secrete their contents?
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Which of the following hormones is both a hormone and a neurotransmitter?
Which of the following hormones is both a hormone and a neurotransmitter?
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What is one of the functions of transport proteins for lipid-soluble hormones?
What is one of the functions of transport proteins for lipid-soluble hormones?
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Which gland is NOT part of the endocrine system?
Which gland is NOT part of the endocrine system?
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Which type of hormone binds to receptors within the cytoplasm or nucleus of a cell?
Which type of hormone binds to receptors within the cytoplasm or nucleus of a cell?
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Which is a function of hormones?
Which is a function of hormones?
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How do paracrine hormones function?
How do paracrine hormones function?
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Which hormone is categorized as a steroid hormone?
Which hormone is categorized as a steroid hormone?
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Which hormone is classified as an amine hormone derived from histidine?
Which hormone is classified as an amine hormone derived from histidine?
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Which hormone increases the levels of cAMP in cells?
Which hormone increases the levels of cAMP in cells?
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Which of the following is a second messenger used by water-soluble hormones?
Which of the following is a second messenger used by water-soluble hormones?
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What effect does serotonin have on hormone activity?
What effect does serotonin have on hormone activity?
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Which hormone interaction requires simultaneous exposure to a second hormone?
Which hormone interaction requires simultaneous exposure to a second hormone?
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During childbirth, which hormone increases uterine contractions?
During childbirth, which hormone increases uterine contractions?
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How is hormone secretion generally controlled?
How is hormone secretion generally controlled?
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What stimulates the release of parathyroid hormone (PTH)?
What stimulates the release of parathyroid hormone (PTH)?
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Which hormone increases flexibility of the pubic symphysis during pregnancy?
Which hormone increases flexibility of the pubic symphysis during pregnancy?
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What is the main hormone produced and secreted by the testes?
What is the main hormone produced and secreted by the testes?
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Which hormone is involved in regulating blood calcium levels?
Which hormone is involved in regulating blood calcium levels?
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What is the function of inhibin in both males and females?
What is the function of inhibin in both males and females?
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What hormone does the pineal gland secrete?
What hormone does the pineal gland secrete?
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Which hormone secreted by the kidneys increases red blood cell production?
Which hormone secreted by the kidneys increases red blood cell production?
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Which of the following is NOT a function of estrogens and progesterone?
Which of the following is NOT a function of estrogens and progesterone?
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Which gland secretes atrial natriuretic peptide (ANP)?
Which gland secretes atrial natriuretic peptide (ANP)?
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Which gland is the major link between the nervous and endocrine systems?
Which gland is the major link between the nervous and endocrine systems?
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What hormone is released by the posterior pituitary in response to elevated blood osmotic pressure?
What hormone is released by the posterior pituitary in response to elevated blood osmotic pressure?
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Which hormone stimulates the liver to secrete insulinlike growth factors (IGFs)?
Which hormone stimulates the liver to secrete insulinlike growth factors (IGFs)?
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What hormone is secreted in darkness by the pineal gland?
What hormone is secreted in darkness by the pineal gland?
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What principal actions does oxytocin (OT) perform?
What principal actions does oxytocin (OT) perform?
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What hormone inhibits the release of corticotropin by anterior pituitary corticotrophs?
What hormone inhibits the release of corticotropin by anterior pituitary corticotrophs?
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Which hormone is involved in elevating blood glucose concentration?
Which hormone is involved in elevating blood glucose concentration?
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What is the function of follicle-stimulating hormone (FSH) in males?
What is the function of follicle-stimulating hormone (FSH) in males?
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The pineal gland secretes a hormone important for what function?
The pineal gland secretes a hormone important for what function?
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What does the anterior pituitary do in response to hypothalamic inhibiting hormones?
What does the anterior pituitary do in response to hypothalamic inhibiting hormones?
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Study Notes
Endocrine System
- Coordinates all body systems with the nervous system
- Uses hormones produced by endocrine structures to produce effects
Endocrine Glands
- Secrete contents directly into the blood
- Include: pituitary, thyroid, parathyroid, adrenal, and pineal glands
Exocrine Glands
- Secrete contents into a lumen or duct
- Include: sudoriferous, sebaceous, mucous, and digestive glands
Hormone Functions
- Regulate:
- Extracellular fluid homeostasis
- Metabolism
- Muscle contraction
- Glandular secretions
- Some immune functions
- Involved in:
- Growth and development
- Reproduction
- Establishing circadian rhythms
Endocrine Hormones
- Secreted into interstitial fluid and then absorbed into the bloodstream
- Can act on any cell with the appropriate receptor
Local Hormones
- Autocrine hormones: act on the same cell that secretes them
- Paracrine hormones: act on nearby cells
- Examples: IL-2, NO
Lipid-Soluble Hormones
- Bind to receptors in the cytoplasm or nucleus of a cell
- Examples: steroid hormones (aldosterone, cortisol, testosterone, oestrogen), thyroid hormones (T3, T4), and gases (nitric oxide)
Thyroid Gland
- Located inferior to the larynx and anterior to the trachea
- Triggers growth of the nervous and skeletal systems
Thyroid Hormones
- Actions:
- Regulate metabolism
- Involved in growth and development
- Establish circadian rhythms
- Regulated by:
- Thyroid-stimulating hormone (TSH)
- Thyrotropin-releasing hormone (TRH)
Parathyroid Glands
- Located on the posterior surface of the thyroid gland
- Secrete parathyroid hormone (PTH) in response to low blood calcium levels
- Actions:
- Regulate blood calcium levels
Pancreatic Hormones
- Include:
- Glucagon
- Insulin
- Somatostatin
- Gastrin
- Secretin
- Cholecystokinin (CCK)
- Glucose-dependent insulinotropic polypeptide (GIP)
- Actions:
- Regulate blood glucose levels
- Involved in digestion and absorption of nutrients
Thymus
- Located superior to the heart
- Secretes thymosin
- Actions:
- Promotes proliferation and maturation of T cells
Ovaries
- Produce several steroid hormones:
- Estrogens and progesterone
- Relaxin
- Inhibin
- Actions:
- Regulate female reproductive cycle and oogenesis
- Maintain pregnancy
- Prepare mammary glands for lactation
Testes
- Produce testosterone
- Actions:
- Regulate male reproductive cycle and spermatogenesis
- Involved in development and maintenance of male secondary sex characteristics
Other Endocrine Tissues
- Include:
- Pineal gland
- Hypothalamus
- Pituitary gland
- Heart
- Stomach
- Kidney
- Adrenal glands
- Pancreas
- Small intestine
- Skin
- Liver
Water-Soluble Hormones
- Bind to receptors on the plasma membrane of a cell
- Include:
- Amine hormones
- Peptide hormones
- Eicosanoid hormones
Hormone Interactions
- Responsiveness of target cells depends on:
- Hormone concentration in blood
- Number of hormone receptors on target cells
- Influences of other hormones
- Types of interactions:
- Permissive
- Synergistic
- Antagonistic
Control of Hormone Secretion
- Regulated by:
- Signals from the nervous system
- Chemical changes in the blood
- Other hormones
- Types of control:
- Negative feedback
- Positive feedback
Hypothalamus and Pituitary Gland
- Hypothalamus: major link between the nervous and endocrine systems
- Pituitary gland: regulates other endocrine glands
- Anterior pituitary: stimulated by releasing hormones from the hypothalamus
- Posterior pituitary: stores and releases hormones produced by the hypothalamus
Pineal Gland
- Secretes melatonin
- Involved in maintaining the biological clock (seasonal and daily cycles)
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Description
Learn about the nervous and endocrine systems, their functions, and the types of glands involved. Understand how they coordinate body systems and produce effects.