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Questions and Answers
Which connective tissue layer directly encloses individual nerve axons?
Which connective tissue layer directly encloses individual nerve axons?
What is the primary function of motor nerves?
What is the primary function of motor nerves?
A nerve containing both sensory and motor fibers is classified as a:
A nerve containing both sensory and motor fibers is classified as a:
The ability of neurons to respond to stimuli is best described as:
The ability of neurons to respond to stimuli is best described as:
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What is the role of the perineurium in nerve structure?
What is the role of the perineurium in nerve structure?
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Which term describes the propagation of electrical impulses along a neuron's membrane?
Which term describes the propagation of electrical impulses along a neuron's membrane?
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Which layer of connective tissue provides the outermost encasement for an entire nerve?
Which layer of connective tissue provides the outermost encasement for an entire nerve?
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What is the defining characteristic of sensory nerves?
What is the defining characteristic of sensory nerves?
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Neurons are specialized for transmitting information rapidly and accurately. This is an example of:
Neurons are specialized for transmitting information rapidly and accurately. This is an example of:
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Which of these are key components of nerve structure?
Which of these are key components of nerve structure?
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Which layer of the cerebral cortex is characterized by the presence of lipofuscin inclusions, indicating cellular aging?
Which layer of the cerebral cortex is characterized by the presence of lipofuscin inclusions, indicating cellular aging?
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Direct current flow through gap junctions is a characteristic of which type of synapse?
Direct current flow through gap junctions is a characteristic of which type of synapse?
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In the context of synaptic transmission, which type relies on the release of neurotransmitters?
In the context of synaptic transmission, which type relies on the release of neurotransmitters?
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Which layer of the cerebral cortex directly precedes the multiform layer?
Which layer of the cerebral cortex directly precedes the multiform layer?
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What distinguishes the function of an electrical synapse in reflex pathways?
What distinguishes the function of an electrical synapse in reflex pathways?
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Which of the following is a characteristic inclusion associated with cellular aging?
Which of the following is a characteristic inclusion associated with cellular aging?
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Amyloid plaques and neurofibrillary tangles are most closely associated with which condition?
Amyloid plaques and neurofibrillary tangles are most closely associated with which condition?
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Which layer is most likely to show signs of lipofuscin accumulation?
Which layer is most likely to show signs of lipofuscin accumulation?
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What is the primary function of the Nodes of Ranvier in neuron physiology?
What is the primary function of the Nodes of Ranvier in neuron physiology?
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Which glial cells are responsible for the production of myelin in the peripheral nervous system (PNS)?
Which glial cells are responsible for the production of myelin in the peripheral nervous system (PNS)?
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Which of the following is a key function of ependymal cells?
Which of the following is a key function of ependymal cells?
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What is the role of satellite cells within the peripheral nervous system (PNS)?
What is the role of satellite cells within the peripheral nervous system (PNS)?
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What is a unique characteristic of Schwann cells regarding myelination?
What is a unique characteristic of Schwann cells regarding myelination?
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What is the primary role of oligodendrocytes within the central nervous system?
What is the primary role of oligodendrocytes within the central nervous system?
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Which glial cells primarily contribute to the inhibitory environment that hinders nerve regeneration after CNS damage?
Which glial cells primarily contribute to the inhibitory environment that hinders nerve regeneration after CNS damage?
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Which of the following best describes the function of a myelin sheath?
Which of the following best describes the function of a myelin sheath?
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What is the primary functional difference between oligodendrocytes and Schwann cells?
What is the primary functional difference between oligodendrocytes and Schwann cells?
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What role do astrocytes play within the central nervous system?
What role do astrocytes play within the central nervous system?
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What is the consequence of glial scar formation in the context of CNS damage?
What is the consequence of glial scar formation in the context of CNS damage?
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Which glial cells are responsible for the phagocytic removal of cellular debris in the CNS?
Which glial cells are responsible for the phagocytic removal of cellular debris in the CNS?
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Which of the following is an example of an inhibitory neurotransmitter within the CNS?
Which of the following is an example of an inhibitory neurotransmitter within the CNS?
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In Parkinson's disease, which specific neuronal population experiences significant loss?
In Parkinson's disease, which specific neuronal population experiences significant loss?
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What is the primary pathological process observed in Multiple Sclerosis (MS)?
What is the primary pathological process observed in Multiple Sclerosis (MS)?
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What structure is primarily affected in Guillain-Barré Syndrome?
What structure is primarily affected in Guillain-Barré Syndrome?
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Which factor primarily contributes to the more effective axonal regeneration observed in the peripheral nervous system (PNS) compared to the central nervous system (CNS)?
Which factor primarily contributes to the more effective axonal regeneration observed in the peripheral nervous system (PNS) compared to the central nervous system (CNS)?
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Which of the following is a key component of the synapse where neurotransmitters are released?
Which of the following is a key component of the synapse where neurotransmitters are released?
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What is the space between the presynaptic and postsynaptic membranes called?
What is the space between the presynaptic and postsynaptic membranes called?
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Which structure is primarily responsible for coordinating movement and maintaining balance?
Which structure is primarily responsible for coordinating movement and maintaining balance?
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Which of the following neurotransmitters is considered excitatory?
Which of the following neurotransmitters is considered excitatory?
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What is the main function of the tissue categorized as periosteum?
What is the main function of the tissue categorized as periosteum?
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Where are neurotransmitter receptors primarily located?
Where are neurotransmitter receptors primarily located?
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Which part of the central nervous system is mainly involved in higher cognitive functions and sensory interpretation?
Which part of the central nervous system is mainly involved in higher cognitive functions and sensory interpretation?
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The brainstem plays a crucial role in which of the following involuntary functions?
The brainstem plays a crucial role in which of the following involuntary functions?
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What is the anatomical relationship between the scalp and the skull?
What is the anatomical relationship between the scalp and the skull?
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What is the primary function of satellite cell nuclei?
What is the primary function of satellite cell nuclei?
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Which of the following sequences accurately represents the flow of structural layers from exterior to interior?
Which of the following sequences accurately represents the flow of structural layers from exterior to interior?
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What is the correct arrangement of white and grey matter in the cerebrum?
What is the correct arrangement of white and grey matter in the cerebrum?
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What is the correct arrangement of white and grey matter in the brainstem?
What is the correct arrangement of white and grey matter in the brainstem?
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Flashcards
Endoneurium
Endoneurium
Connective tissue layer surrounding each individual axon within a nerve.
Fascicles
Fascicles
Bundles of nerve fibers (axons) within a nerve.
Perineurium
Perineurium
Connective tissue layer that encloses fascicles (bundles of nerve fibers) within a nerve.
Epineurium
Epineurium
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Sensory Nerves
Sensory Nerves
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Motor Nerves
Motor Nerves
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Mixed Nerves
Mixed Nerves
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Excitability
Excitability
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Conductivity
Conductivity
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Neurons
Neurons
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Scalp
Scalp
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Brain
Brain
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Cerebrum
Cerebrum
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Cerebellum
Cerebellum
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Brainstem
Brainstem
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White matter
White matter
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Gray matter
Gray matter
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Satellite cells
Satellite cells
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Periosteum
Periosteum
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Central Nervous System (CNS)
Central Nervous System (CNS)
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Inner Granular Layer (IV)
Inner Granular Layer (IV)
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Lipofuscin
Lipofuscin
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Ganglion Layer (V)
Ganglion Layer (V)
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Multiform Layer (VI)
Multiform Layer (VI)
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Electrical Synapse
Electrical Synapse
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Chemical Synapse
Chemical Synapse
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Alzheimer's Disease
Alzheimer's Disease
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Multiform Layer ( VI )
Multiform Layer ( VI )
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Parkinson's Disease
Parkinson's Disease
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Multiple Sclerosis (MS)
Multiple Sclerosis (MS)
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Guillain-Barré Syndrome (GBS)
Guillain-Barré Syndrome (GBS)
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Synapse
Synapse
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Presynaptic Terminal
Presynaptic Terminal
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Synaptic Cleft
Synaptic Cleft
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Postsynaptic Membrane
Postsynaptic Membrane
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Excitatory Neurotransmitters
Excitatory Neurotransmitters
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Neuroglia (Glial Cells)
Neuroglia (Glial Cells)
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Nodes of Ranvier
Nodes of Ranvier
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Schwann Cells
Schwann Cells
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Ependymal Cells
Ependymal Cells
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Myelin Sheath
Myelin Sheath
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Oligodendrocytes
Oligodendrocytes
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Astrocytes
Astrocytes
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Microglia
Microglia
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GABA
GABA
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CNS Damage and Recovery
CNS Damage and Recovery
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Myelination
Myelination
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Study Notes
Nerve Tissue Histology Mind Map
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Nerve Tissue Overview: The nervous system is composed of nerve tissue, which includes neurons and neuroglia. Neurons are the functional units, transmitting signals. Neuroglia support and protect neurons.
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Neuron Structure: Neurons consist of a cell body (soma), dendrites (receiving signals), and an axon (sending signals). The axon may be myelinated (for faster signal transmission) or unmyelinated. Myelin is produced by Schwann cells in the peripheral nervous system (PNS) and oligodendrocytes in the central nervous system (CNS). Nodes of Ranvier are gaps in the myelin sheath where action potentials regenerate.
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Neuroglia: Neuroglia (glial cells) support neurons and maintain homeostasis. Types include astrocytes (regulate blood-brain barrier), oligodendrocytes (produce myelin in CNS), microglia (immune cells), and ependymal cells (produce cerebrospinal fluid). Schwann cells in the PNS myelinate single axons, while satellite cells support neurons in ganglia.
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Nerve Types: Nerves can be sensory (transmit sensory data), motor (carry motor commands), or mixed (contain both). Nerves are bundles of axons and connective tissues. Layers include epineurium (outermost), perineurium (surrounds fascicles), and endoneurium (surrounds individual axons).
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Synapses: Neurons communicate via synapses, where a neurotransmitter is released from one neuron to stimulate an adjacent neuron. Synapses can be chemical (mediated by neurotransmitters) or electrical (direct current, gap junctions).
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CNS (Central Nervous System): Includes the brain and spinal cord. Grey matter contains neuronal cell bodies and numerous synapses. White matter is primarily composed of myelinated axons. Distinct layers of the cerebral cortex like molecular (1), outer granular (II), outer pyramidal (III), inner granular (IV), ganglion (V), and multiform (VI).
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PNS (Peripheral Nervous System): Includes nerves and ganglia. Nerves connect the CNS to the body. Ganglia are clusters of neuronal cell bodies outside the CNS. Somatic nervous system (voluntary control of skeletal muscles) and autonomic nervous system (involuntary control of smooth muscles, glands, internal organs) is a part of the PNS. The sympathetic and parasympathetic divisions compose the autonomic nervous system.
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Meninges: Dura mater, arachnoid mater, and pia mater are protective membranes covering the brain and spinal cord. Dura mater is the outermost tough membrane. Arachnoid mater is a web-like middle layer that contains arachnoid villi for CSF reabsorption. Pia mater is a thin inner layer that closely adheres to the brain's surface.
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Neurodegenerative and Demyelinating Diseases: Diseases like Alzheimer's (amyloid plaques and neurofibrillary tangles), Parkinson's (loss of dopaminergic neurons), Multiple Sclerosis (CNS myelin damage), and Guillain-Barré syndrome (PNS myelin damage).
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Axonal Regeneration: Regeneration is more effective in the PNS than in the CNS. Schwann cells in the PNS help for regeneration while CNS has an inhibitory environment created by glial scar formation inhibiting regeneration.
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Functional Divisions of the Nervous System: Sensory Input - Detects environmental changes. Integration - Processes and interprets sensory information. Motor Output - Transmits signals to effectors. Higher Functions - Cognition, emotion, memory, learning.
Cell Body (Soma)
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Contains the nucleus and organelles, synthesizes neurotransmitters.
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Dendrites: Branching processes that receive input signals from other neurons or sensory stimuli.
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Axon: Long projection that transmits electrical impulses away from the soma.
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Axon Hillock: Region where action potentials are initiated in the axon.
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Axon Terminals: Release neurotransmitters to target cells.
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Cytoskeleton: Neurofilaments, microtubules (transport), microfilaments support the structure and function.
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Organelles: Nissl bodies (rough ER for protein synthesis), mitochondria (high energy demands). Inclusions include melanin or lipofuscin (cellular aging).
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Description
Explore the fundamental aspects of nerve tissue histology, including the structure and function of neurons and neuroglia. Understand how neurons transmit signals and the role of various glial cells in supporting brain function. This quiz covers key terms and concepts essential for studying the nervous system.