Nephrology: Loop of Henle Review

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12 Questions

What percentage of water is reabsorbed in the proximal tubule, which is non-regulated?

70%

What is the minimum volume of water that must be excreted in urine per day?

440 mL

What is the maximum osmolarity of urine?

1400 mOsm

In which part of the nephron is water reabsorption regulated by ADH?

Collecting duct

What percentage of water is reabsorbed in the distal tubules, which is regulated by ADH?

20%

What is the role of the medullary osmotic gradient in water reabsorption?

It facilitates water reabsorption

What is the main function of aquaporins in the descending loop of Henle?

To make the descending loop permeable to water

What is the primary role of urea in the nephron?

To generate the necessary osmotic gradient in the loop of Henle

What is the name of the capillaries surrounding the loop of Henle and nephrons?

Vasa recta

What is the direction of water movement in the descending limb of the vasa recta?

From the capillaries into the interstitial fluid

What is the primary function of the urea transporter A (UTA) in the nephron?

To transport urea from the filtrate to the peritubular fluid

What is the direction of fluid movement in the ascending limb of the vasa recta?

From the interstitial fluid into the capillaries

Review the functions of the descending and ascending loops of Henle in the nephron, including water and solute movement in response to osmotic gradients. Understand how the loops regulate osmolarity and solute concentrations.

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