Podcast
Questions and Answers
What defines a malignant neoplasm?
What defines a malignant neoplasm?
- It can be benign if it remains localized and does not spread.
- It is a cancerous growth that can invade surrounding tissues and spread throughout the body. (correct)
- It is always larger than a benign neoplasm.
- It is a non-cancerous growth that does not invade surrounding tissues.
Which suffix is used to classify benign tumors?
Which suffix is used to classify benign tumors?
- -carcinoma
- -oma (correct)
- -itis
- -sarcoma
What is a shared characteristic of cancer cells?
What is a shared characteristic of cancer cells?
- They do not undergo Darwinian selection.
- They only experience genetic mutations when symptomatic.
- Genetic alterations can be inherited and influence daughter cells. (correct)
- They are always more effective at healing than normal cells.
Which of the following is NOT a characteristic of malignant tumors?
Which of the following is NOT a characteristic of malignant tumors?
How are tumors classified based on their tissue origin?
How are tumors classified based on their tissue origin?
What does the term 'oncology' refer to?
What does the term 'oncology' refer to?
What is a common misconception about tumors?
What is a common misconception about tumors?
What distinguishes cancer from general tumors?
What distinguishes cancer from general tumors?
What does 'carcinoma in situ' refer to?
What does 'carcinoma in situ' refer to?
What is the role of stroma in relation to cancer cells?
What is the role of stroma in relation to cancer cells?
What is indicated by the term 'more parenchymal' in tumor consistency?
What is indicated by the term 'more parenchymal' in tumor consistency?
How does the stroma influence the firmness of a tumor?
How does the stroma influence the firmness of a tumor?
Which characteristic distinguishes a malignant tumor from a benign tumor?
Which characteristic distinguishes a malignant tumor from a benign tumor?
What is the primary indicator of malignancy among tumors?
What is the primary indicator of malignancy among tumors?
Which option correctly describes benign tumors?
Which option correctly describes benign tumors?
What term describes cells that divide uncontrollably and form a tumor?
What term describes cells that divide uncontrollably and form a tumor?
What term describes the lack of differentiation in tumor cells, often a hallmark of malignancy?
What term describes the lack of differentiation in tumor cells, often a hallmark of malignancy?
Which feature distinguishes benign tumors from malignant tumors?
Which feature distinguishes benign tumors from malignant tumors?
What is the first regional lymph node that receives lymph flow from a primary tumor called?
What is the first regional lymph node that receives lymph flow from a primary tumor called?
What is typically true about well-differentiated malignant tumors?
What is typically true about well-differentiated malignant tumors?
Which term describes the spread of cancer cells through the bloodstream?
Which term describes the spread of cancer cells through the bloodstream?
Dysplasia primarily indicates a condition where cells are:
Dysplasia primarily indicates a condition where cells are:
Malignant tumors frequently exhibit which of the following characteristics?
Malignant tumors frequently exhibit which of the following characteristics?
What does carcinoma in situ signify?
What does carcinoma in situ signify?
Which type of tumor is most likely to spread through the lymphatic system?
Which type of tumor is most likely to spread through the lymphatic system?
Which of the following traits can signify severe dysplasia?
Which of the following traits can signify severe dysplasia?
Which of these cancers primarily spreads through the bloodstream?
Which of these cancers primarily spreads through the bloodstream?
What is the defining characteristic of benign tumors?
What is the defining characteristic of benign tumors?
What is the main role of stroma in a tumor?
What is the main role of stroma in a tumor?
Which of the following tumors is classified as a benign tumor?
Which of the following tumors is classified as a benign tumor?
Which suffix is typically used to denote a benign tumor?
Which suffix is typically used to denote a benign tumor?
What type of tumor is classified as a malignant tumor arising from mesenchymal tissue?
What type of tumor is classified as a malignant tumor arising from mesenchymal tissue?
What distinguishes mixed tumors from other tumor types?
What distinguishes mixed tumors from other tumor types?
Which of the following is an example of a malignant tumor that does not follow the typical naming convention?
Which of the following is an example of a malignant tumor that does not follow the typical naming convention?
What type of carcinoma forms gland-like structures?
What type of carcinoma forms gland-like structures?
Which of the following describes a teratoma?
Which of the following describes a teratoma?
What is a key characteristic of a pleomorphic adenoma?
What is a key characteristic of a pleomorphic adenoma?
Which term refers to a mass of disorganized, normal tissue found in the location where the tumor arises?
Which term refers to a mass of disorganized, normal tissue found in the location where the tumor arises?
Which of the following defines a carcinoma?
Which of the following defines a carcinoma?
What type of blood-forming cell tumor is characterized as malignant?
What type of blood-forming cell tumor is characterized as malignant?
What is the main difference between a hamartoma and a choristoma?
What is the main difference between a hamartoma and a choristoma?
Which type of tumor can contain tissues from multiple germ layers?
Which type of tumor can contain tissues from multiple germ layers?
Flashcards
Neoplasm
Neoplasm
An abnormal growth of tissue that can be either benign (non-cancerous) or malignant (cancerous).
Benign Neoplasm
Benign Neoplasm
A non-cancerous neoplasm that does not spread to other parts of the body. It may cause problems if it grows large or presses on nearby structures.
Malignant Neoplasm
Malignant Neoplasm
A cancerous neoplasm that can invade surrounding tissues and spread to other parts of the body (metastasis). These are dangerous because they disrupt normal organ function and can be life-threatening.
Tumor
Tumor
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Cancer
Cancer
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Nomenclature of Neoplastic Diseases
Nomenclature of Neoplastic Diseases
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Benign Tumor Naming
Benign Tumor Naming
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Malignant Tumor Naming
Malignant Tumor Naming
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Parenchyma
Parenchyma
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Stroma
Stroma
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Polyps
Polyps
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Papillomas
Papillomas
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Sarcomas
Sarcomas
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Carcinomas
Carcinomas
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Adenocarcinoma
Adenocarcinoma
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Squamous Cell Carcinoma
Squamous Cell Carcinoma
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Mixed Tumors
Mixed Tumors
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Pleomorphic Adenoma
Pleomorphic Adenoma
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Teratoma
Teratoma
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Hamartoma
Hamartoma
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Choristomas
Choristomas
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Lymphoma
Lymphoma
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Carcinoma in situ
Carcinoma in situ
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Desmoplastic Tumor
Desmoplastic Tumor
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Softer Tumor
Softer Tumor
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Metastasis
Metastasis
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Differentiation
Differentiation
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Benign Tumor
Benign Tumor
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Malignant Tumor
Malignant Tumor
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Differentiation in Tumors
Differentiation in Tumors
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Anaplasia
Anaplasia
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Pleomorphism
Pleomorphism
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Local Invasion
Local Invasion
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Encapsulated Tumor
Encapsulated Tumor
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Seeding Metastasis
Seeding Metastasis
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Lymphatic Spread
Lymphatic Spread
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Hematogenous Spread
Hematogenous Spread
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Sentinel Lymph Node
Sentinel Lymph Node
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Dysplasia
Dysplasia
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Lipoma
Lipoma
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Study Notes
Neoplasms and Nomenclature
- Neoplasms are abnormal tissue growths, either benign (non-cancerous) or malignant (cancerous).
- Benign neoplasms do not spread and are usually not life-threatening, though they can cause problems if growing large.
- Malignant neoplasms spread and invade, posing a serious threat to life; an example is melanoma.
- Tumor and neoplasm are often used interchangeably; a tumor is any abnormal tissue growth, while a neoplasm is abnormally growing cells.
Shared Characteristics of Cancer
- Cancer is a genetic disorder.
- DNA mutations are inheritable, allowing cancer cells to proliferate and survive.
- Genetic and epigenetic changes give cancer cells "cancer hallmarks" enabling uncontrolled growth, evasion of defenses, and metastasis.
Nomenclature of Neoplastic Diseases
- Tumors are classified based on tissue origin:
- Benign tumors typically end in "-oma" (e.g., fibroma).
- Malignant tumors are named by tissue origin, with "-sarcoma" for mesenchymal (e.g., osteosarcoma) and "-carcinoma" for epithelial tumors (e.g., adenocarcinoma).
Basic Components of Tumors
- Tumors have two main parts:
- Parenchyma: The transformed tumor cells (that determine tumor behavior).
- Stroma: The support tissue (connective tissue, blood vessels) for tumor growth.
Benign Tumors
- Named with "-oma" suffix, based on cell or tissue type.
- Examples: Fibroma (fibrous tissue), Chondroma (cartilage), Adenoma (glandular epithelium).
- Other types include papillomas, polyps, and cystadenomas.
Malignant Tumors (Cancers)
- Named differently from benign tumors.
- Sarcomas arise from mesenchymal tissues (e.g., liposarcoma, chondrosarcoma).
- Leukemias and lymphomas are blood cell cancers from hematopoietic or lymphatic systems.
- Carcinomas originate from epithelial cells (e.g., adenocarcinomas, squamous cell carcinomas).
Mixed Tumors
- Contain cells from different tissue types (epithelial and mesenchymal).
- Examples: Pleomorphic adenoma (salivary gland), Fibroadenoma (breast).
- Teratomas arise from germ cells, containing multiple tissues.
Exceptions and Confusing Terminology
- Some malignant tumors use the "-oma" suffix (e.g., lymphoma, melanoma, seminoma).
- Hamartomas are masses of disorganized, normal tissue.
- Choristomas are congenital tissue masses in abnormal locations.
Characteristics Differentiating Benign and Malignant Neoplasms
-
Differentiation (and Anaplasia)
- Benign: Well-differentiated cells.
- Malignant: Poorly differentiated (anaplastic) cells, with changes like pleomorphism and abnormal mitosis.
-
Local Invasion:
- Benign: Grow as cohesive units, often with a capsule.
- Malignant: Invade surrounding tissues, without clear boundaries.
-
Metastasis
- Benign: Do not spread to other organs.
- Malignant: Spread to distant organs (lymphatic or hematogenous spread)
-
Dysplasia and Carcinoma In Situ:
- Dysplasia: Disordered cell growth, but still confined.
- Carcinoma In Situ: Abnormal cells but haven't invaded surrounding tissues.
-
Tumor Consistency and Stroma:
- Tumor consistency (firmness) relates to the amount and density of stroma.
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Description
Explore the crucial concepts of neoplasms and their classification. This quiz delves into the differences between benign and malignant tumors, their shared characteristics with cancer, and the nomenclature used in defining neoplastic diseases. Test your knowledge on this important medical topic.