Neoplasia, benign and malignant neoplasms Quiz

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Questions and Answers

Which term describes the abnormal proliferation of cells?

  • Neoplasm
  • Tumour
  • Neoplasia (correct)
  • Cancer

What is the clinical appearance of an abnormal growth called?

  • Neoplasia
  • Tumour
  • Cancer (correct)
  • Neoplasm

Which type of growth does not invade surrounding tissue or spread to new locations in the body?

  • Pre-malignant
  • Carcinoma
  • Benign (correct)
  • Malignant

Which type of growth lacks invasion of the basement membrane but becomes malignant once invasion occurs?

<p>Pre-malignant (C)</p> Signup and view all the answers

Which type of growth interferes with and ultimately kills the organism?

<p>Malignant (C)</p> Signup and view all the answers

What is the process of gradual stepwise tumor development called?

<p>Oncogenesis (D)</p> Signup and view all the answers

Which type of neoplasm is a malignant neoplasm that originates from epithelium?

<p>Carcinoma (C)</p> Signup and view all the answers

Which step of oncogenesis involves the introduction of an irreversible genetic change?

<p>Initiation (D)</p> Signup and view all the answers

Which cells can be resistant to apoptosis?

<p>Initiated cells (D)</p> Signup and view all the answers

In terms of oncogenesis, what is the second step in the sequence of steps for carcinoma development?

<p>Epidermal hypoplasia (A)</p> Signup and view all the answers

Which of the following is a characteristic of a malignant neoplasm?

<p>Frequent metastasis (A)</p> Signup and view all the answers

Which of the following is a characteristic of a benign neoplasm?

<p>Cohesive growth (B)</p> Signup and view all the answers

Which of the following is a characteristic of a malignant neoplasm based on cytological features?

<p>Marked anisokaryosis (D)</p> Signup and view all the answers

Which of the following is a characteristic of a benign neoplasm based on cytological features?

<p>Minimal to mild anisocytosis (C)</p> Signup and view all the answers

Which type of neoplasm affects the lining epithelium?

<p>Squamous cell carcinoma (C)</p> Signup and view all the answers

Which type of neoplasm affects connective tissue?

<p>Lipoma (C)</p> Signup and view all the answers

Which phase of tumor development is characterized by genetic instability and increasing tumor cell heterogeneity?

<p>Progression (A)</p> Signup and view all the answers

Which phase of tumor development is characterized by the development of a preneoplastic lesion or a benign tumor?

<p>Promotion (D)</p> Signup and view all the answers

Which factor is responsible for driving proliferation of neoplastic cells during promotion?

<p>Selective stimulation (D)</p> Signup and view all the answers

Which characteristic is important for characterizing neoplasms and involves the absence of invasiveness to surrounding tissue?

<p>Differentiation (A)</p> Signup and view all the answers

Which type of neoplasm affects the muscle?

<p>Fibrosarcoma (C)</p> Signup and view all the answers

Which type of neoplasm affects the lining epithelium?

<p>Adenocarcinoma (C)</p> Signup and view all the answers

Which type of neoplasm affects the nervous system?

<p>Oligodendroglioma (D)</p> Signup and view all the answers

Which type of agent can cause mutagenesis during the initiation phase of oncogenesis?

<p>All of the above (D)</p> Signup and view all the answers

What is the main characteristic of promotors during the promotion phase of oncogenesis?

<p>They are non-mutagenic (C)</p> Signup and view all the answers

What is a hallmark of the progression phase of tumor development?

<p>Both genetic instability and increasing tumor cell heterogeneity (C)</p> Signup and view all the answers

Which type of neoplasm can become metastatic and is characterized by irreversible change?

<p>Malignant neoplasm (B)</p> Signup and view all the answers

What are the main factors responsible for selecting increasingly malignant clones of tumor cells during progression?

<p>Both genetic and epigenetic changes (C)</p> Signup and view all the answers

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