Neoplasia: Definition, Classification, and Causes
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Questions and Answers

Which type of lymphoma is most strongly associated with Helicobacter pylori infections?

  • B-cell lymphoma of the stomach (correct)
  • Follicular lymphoma
  • T-cell lymphoma
  • Mantle zone lymphoma

    • What is the mechanism by which chemical carcinogens can lead to cancer development?

  • They cause direct DNA damage leading to mutations. (correct)
  • They require metabolic conversion to an active form to become carcinogenic.
  • Both direct-acting and indirect-acting carcinogens work through the same mechanism.
  • They stimulate cell proliferation without causing DNA damage.

    • Which of the following is NOT a mechanism by which tumor promoters can enhance tumorigenesis?

  • Causing DNA damage and mutations in cells. (correct)
  • Increasing the conversion of indirect-acting carcinogens to active forms.
  • Directly stimulating the proliferation of mutated cells.
  • Inducing tissue injury and regenerative repair.

    • What is the primary mechanism by which ionizing radiation can lead to carcinogenesis?

    <p>Both a and b</p> Signup and view all the answers

    Which of the following is NOT a common paraneoplastic syndrome associated with tumors?

    <p>Tissue injury and regenerative repair</p> Signup and view all the answers

    Which of the following inherited genetic syndromes is associated with an increased risk of colorectal cancer?

    <p>Lynch syndrome</p> Signup and view all the answers

    What is the primary difference between tumor grading and tumor staging?

    <p>Grading is of greater clinical value than staging in predicting tumor behavior and prognosis.</p> Signup and view all the answers

    Which of the following is NOT a characteristic of direct-acting chemical carcinogens?

    <p>They require metabolic conversion to become carcinogenic.</p> Signup and view all the answers

    What is the primary mechanism by which UV radiation from sunlight can lead to the development of skin cancers?

    <p>Causing the formation of pyrimidine dimers in DNA, leading to mutations.</p> Signup and view all the answers

    Which of the following inherited genetic syndromes is associated with an increased risk of breast and ovarian cancer?

    <p>Hereditary breast and ovarian cancer syndrome</p> Signup and view all the answers

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