proteins chem section

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26 Questions

Which protein is a negative acute phase reactant?

Haptoglobin

Which protein is involved in defense or protective function?

CRP

Which protein is a positive acute phase reactant?

Transthyretin

What is the main cause of hyperproteinemia?

Increased γ-globulin

Which immunoglobulin is associated with long-term immunity?

IgG

Which immunoglobulin is the first to be produced in an immune response?

IgM

Which immunoglobulin is associated with Type I hypersensitivities?

IgE

Which immunoglobulin is found on the surface of mature B lymphocytes?

IgD

What is the rate-limiting step of bilirubin metabolism?

Excretion of bile

Which of the following is true about enzymes?

Enzymes speed up reactions by increasing substrate specificity.

What is the optimal temperature for enzyme activity?

37°C

Which protein is synthesized by the fetal yolk sac and parenchymal cells of the fetal liver?

α1-FETOPROTEIN (AFP)

What is the function of Haptoglobin?

Bind free Hb to prevent loss of Hb via urine

Which protein is a precursor to angiotensin I?

Angiotensinogen

Which protein is an acute phase reactant and increases in inflammatory conditions?

Ceruloplasmin

Which enzyme catalyzes the transamination reactions of amino acids?

Alanine aminotransferase (ALT)

Which enzyme is associated with damaged hepatobiliary cells?

Aspartate aminotransferase (AST)

Which enzyme is associated with hepatocellular and obstructive disorders?

γ-glutamyl transferase (GGT)**GSH/GSSG, Glutathione

Which enzyme is responsible for the reversible phosphorylation of Creatine?

Creatine Kinase (CK/CPK)

Which enzyme is unstable in serum due to oxidation of its active site?

Creatine Kinase (CK/CPK)

Which enzyme has the highest activity in muscle tissue?

Creatine Kinase (CK/CPK)

Which enzyme is responsible for the reversible reaction of pyruvate to lactate?

Lactate Dehydrogenase (LD/LDH)

Which enzyme is recommended to be measured by monitoring NADH at 340 nm?

Lactate Dehydrogenase (LD/LDH)

Where does the absorption of amino acids (aa) primarily occur in the digestive system?

Jejunum

What is the normal range of total protein in the serum?

Approximately 6.5-8.3 g/dl

What is the main protein responsible for filtering and reabsorption in the kidneys?

Uromodulin

Test your knowledge on the causes and risks associated with neonatal jaundice. Learn about the different types, including Type II inherited jaundice, and the potential complications such as encephalopathy.

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