Neocerebellar Syndrome Quiz

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Questions and Answers

What symptom is most commonly associated with neocerebellar syndrome?

  • Dysmetria
  • Increased intracranial pressure
  • Hypotonia (correct)
  • Papilledema

Which of the following best differentiates cerebellar ataxia from somatosensory ataxia?

  • Comparison of coordination with eyes open and eyes closed (correct)
  • The presence of intention tremor
  • Listlessness and vomiting
  • The wavy trajectory of movement

What is the primary role of the cerebellum in motor control?

  • To modulate cortical signals sent to lower motor neurons (correct)
  • To directly initiate muscle contractions
  • To influence the autonomic nervous system
  • To store sensory information for reflexes

Which of the following statements about medulloblastoma is true?

<p>Symptoms can include headaches and vomiting (B)</p> Signup and view all the answers

What is the prognosis for restoration of normal function following cerebellar injury?

<p>Complicated and poor (B)</p> Signup and view all the answers

Which of the following describes a characteristic of hyperkinetic disorders?

<p>Slow, writhing, twisting movements (B), Sustained involuntary contractions of muscles (C)</p> Signup and view all the answers

What type of tremor is associated with Parkinson's Disease?

<p>Resting tremor (B)</p> Signup and view all the answers

How does hemiballismus primarily affect muscle movement?

<p>Large amplitude flailing motions of one side of the body (A)</p> Signup and view all the answers

Which symptom is commonly associated with Huntington’s Disease?

<p>Chorea and dementia (C)</p> Signup and view all the answers

What is the primary role of the basal ganglia in motor function?

<p>Regulating the initiation and coordination of movement (D)</p> Signup and view all the answers

Which condition primarily involves rapid, irregular, jerky movements?

<p>Chorea (B)</p> Signup and view all the answers

What distinguishes intention tremor from resting tremor?

<p>Occurs during action vs. at rest (A)</p> Signup and view all the answers

Which of the following is not a symptom associated with the basal ganglia disorders?

<p>Ataxia (C)</p> Signup and view all the answers

What is the primary reason that the severity of cerebellar deficits may not reflect the magnitude of damage?

<p>The cerebellum's small and compact space makes assessment difficult. (C)</p> Signup and view all the answers

In motor learning and plasticity, which mechanism is primarily affected?

<p>Modification of the strength of inhibition of the cortical inhibitory loop. (A)</p> Signup and view all the answers

Which structure is NOT a component of the cerebellar circuitry?

<p>Hippocampus. (C)</p> Signup and view all the answers

Where does the cortex primarily communicate with the cerebellum?

<p>Indirectly via the pons. (C)</p> Signup and view all the answers

What role does the vestibulocerebellum serve?

<p>Governing vestibular motor output. (B)</p> Signup and view all the answers

What differentiates spinocerebellum function from cerebrocerebellum function?

<p>Connections to the brainstem versus the cortex. (C)</p> Signup and view all the answers

Which type of issue may arise with deep cerebellar nuclei function?

<p>Uncoordinated movements of arms and legs. (A)</p> Signup and view all the answers

The interposed nuclei of the cerebellum primarily influence which aspect of motor control?

<p>Movements of the arms and legs. (B)</p> Signup and view all the answers

What kind of feedback does the cerebellum utilize for error correction?

<p>Proprioceptive and sensory feedback. (D)</p> Signup and view all the answers

Which of the following conditions may indicate issues in the cerebellar circuitry?

<p>Medial instability. (A)</p> Signup and view all the answers

What is one of the primary functions of the flocculonodular lobe of the cerebellum?

<p>Calibration of vestibular motor output. (A)</p> Signup and view all the answers

The term 'cerebellar ataxia' most commonly refers to which type of disorder?

<p>Movement disorder resulting in poor coordination. (B)</p> Signup and view all the answers

Which of the following is a common challenge encountered with Levodopa treatment in Parkinson’s Disease?

<p>Psychosis and hallucinations. (B)</p> Signup and view all the answers

Flashcards

Cerebellar Function

The cerebellum's role in coordinating movement and maintaining balance.

Dysmetria

The inability to control the range and accuracy of movement; characterized by an inaccurate trajectory.

Cerebellar Dysfunction

Impairment of the cerebellum's function resulting in uneven and inaccurate movements.

Medulloblastoma

A highly malignant brain tumor common in children, typically between the ages of 4-8.

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Neocerebellar Syndrome

A common cerebellar disorder caused by a variety of factors including disease, tumors and cardiovascular problems.

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Intention Tremor

Tremor that occurs as a movement is about to be performed or while being performed, but not while the body is at rest.

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Hypotonia

Lowered muscle tone.

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Asthenia

Loss or weakening of strength.

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Ataxia

Loss of motor control, characterized by uncoordinated movements.

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Somatosensory Ataxia

Ataxia originating from sensory issues in the body.

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Differentiating Ataxas

Using observations from seeing (eyes open) and without (eyes shut) motor movements to differentiate sensory and cerebellar problems respectively.

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Parkinson's Disease

A hypokinetic disorder characterized by tremor, rigidity, akinesia, and postural instability.

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Basal Ganglia

A group of subcortical structures that play a critical role in motor control, and other cognitive functions.

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Striatum

Part of the basal ganglia, composed of the caudate nucleus and putamen, receiving input from the cerebral cortex.

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Tremor (PD tremor)

A common symptom of Parkinson's Disease, involving rhythmic shaking.

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Globus Pallidus

Part of the basal ganglia, with internal and external segments that participate in motor control.

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Rigidity

Muscle stiffness in Parkinson's, often described as cogwheel or lead pipe.

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Substantia Nigra

Midbrain structure in basal ganglia pathway that produces dopamine.

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Cogwheel Rigidity

A type of rigidity with a jerky, stop-and-go quality.

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Subthalamic Nucleus

Part of the basal ganglia, part of indirect pathway and involved in motor circuits.

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Lead Pipe Rigidity

A type of rigidity with consistent and smooth stiffness.

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Hyperkinetic Disorders

Group of movement disorders characterized by excessive, involuntary movements.

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Akinesia

Difficulty initiating movement.

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Parkinson's Disease

A neurodegenerative disease characterized by tremor, rigidity, and bradykinesia.

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Bradykinesia

Slowness of movement.

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Huntington's Disease

A hereditary and progressive neurological disorder, characterized by chorea and dementia.

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Freezing

Sudden inability to move in Parkinson's.

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Chorea

Involves involuntary, rapid, irregular, jerky movements, primarily in the upper extremities.

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Postural Instability

Loss of balance and impaired postural reflexes.

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Levodopa

Medication used to replace dopamine, helping balance dopamine and acetylcholine in the brain.

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Tremor

Involuntary rhythmic movements of a joint.

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On/Off phenomenon

Fluctuations in Parkinson's symptoms, with periods of mobility and immobility.

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Dystonia

Sustained involuntary contractions of muscles causing abnormal posturing or twisting movements.

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Deep Brain Stimulation (DBS)

Surgical procedure using electrodes to stimulate areas of the brain to improve Parkinson's symptoms.

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Athetosis

Slow, involuntary, writhing, or twisting movements, often in the distal extremities.

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Hemiballismus

Large-amplitude, sudden, and violent movements of an arm and leg on one side of the body.

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Parkinson's Disease Questionnaire (PDQ-39)

A subjective measure used to assess the impact of Parkinson's on daily life.

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Tics

Abrupt, repetitive movements or vocalizations.

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Cerebellum

Part of the brain involved in motor coordination and error correction.

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Cerebellar Cortex

Outer layer of the cerebellum.

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Deep Nuclei

Inner structures of the cerebellum.

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Motor Learning

Process of improving movement skills by modifying neuronal pathways.

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Cerebellar Plasticity

The ability of the cerebellum to change and adapt.

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Study Notes

Cerebellar Syndrome & Ataxia

  • Neocerebellar syndrome: Most commonly associated with intention tremor.
  • Cerebellar ataxia vs. Somatosensory ataxia: Cerebellar ataxia manifests with errors in movement coordination, while somatosensory ataxia involves issues with proprioception and balance.
  • Cerebellum's role in motor control: Primarily functions in coordinating and smoothing movements, learning motor skills, and maintaining balance.

Cerebellar Disorders

  • Medulloblastoma: A malignant tumor arising in the cerebellum, primarily affecting children.
  • Prognosis of cerebellar injury: Recovery from cerebellar injury is dependent on the extent of damage, with partial recovery of function being possible.

Motor Control Disorders

  • Hyperkinetic disorders: Characterized by excessive involuntary movements.
  • Parkinson's Disease: Associated with resting tremor which worsens during inactivity.
  • Hemiballismus: Affects muscle movement by causing violent, unilateral flinging movements.
  • Huntington's Disease: Characterized by chorea, uncontrollable jerking movements.

Basal Ganglia & Motor Function

  • Basal ganglia's role: Plays a crucial role in planning, initiating, and regulating movements, as well as controlling muscle tone.
  • Condition with rapid, irregular, jerky movements: Chorea, a symptom associated with Huntington's disease, dystonia, and Tourette syndrome.
  • Intention tremor vs. Resting tremor: Intention tremor occurs during voluntary movement, whereas resting tremor manifests during inactivity.
  • Symptoms NOT associated with basal ganglia disorders: Intention tremor, typically associated with cerebellar dysfunction.
  • Severity of cerebellar deficits: May not directly reflect the magnitude of damage due to the brain's plasticity and compensatory mechanisms.
  • Motor learning and plasticity: Synaptic plasticity is primarily affected in motor learning and plasticity.
  • Structure NOT part of cerebellar circuitry: Basal ganglia.
  • Communication between cortex and cerebellum: The cortex mainly interacts with the cerebellum through the pontocerebellar pathway.

Cerebellum Anatomy & Functions

  • Vestibulocerebellum's role: Crucial for regulating balance and eye movements.
  • Spinocerebellum vs. Cerebrocerebellum: Spinocerebellum regulates muscle tone and coordination of limb movements, while cerebrocerebellum is involved in planning and executing movements.
  • Issues with deep cerebellar nuclei: Can lead to ataxia, dysmetria, and hypotonia.
  • Interposed nuclei's influence: Primarily affect muscle coordination and fine motor control.
  • Feedback utilized by cerebellum: Somatosensory feedback for error correction.

Clinical Considerations

  • Conditions indicating cerebellar circuitry issues: Ataxia, dysmetria, intention tremor, and nystagmus.
  • Flocculonodular lobe's function: Primarily involved in balance and coordination.
  • 'Cerebellar ataxia' refers to: Ataxia caused by cerebellar dysfunction.
  • Challenge with Levodopa treatment in Parkinson's disease: Long-term use can lead to motor fluctuations and dyskinesias.

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