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Questions and Answers

What is the primary function of alveoli?

  • To produce surfactant
  • To deliver nutrients to lung tissue
  • To facilitate gas exchange (correct)
  • To remove clots and debris from the circulation

Which type of alveolar cells produce surfactant in the lungs?

  • Alveolar Ducts
  • Type 2 alveolar cells (correct)
  • Alveolar macrophages
  • Type 1 alveolar cells

What is the role of alveolar macrophages in the respiratory system?

  • Producing oxygen
  • Delivering nutrients to lung tissue
  • Preventing lung collapse
  • Ingesting foreign material and removing it through the lymphatic system (correct)

What is the function of surfactant in the alveoli?

<p>Keeping alveoli open and free of fluid (C)</p>
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How does the pulmonary circulation differ from systemic circulation?

<p>Pulmonary circulation uses high pressure while systemic circulation uses low pressure (C)</p>
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Where does the pulmonary circulation begin?

<p>In the pulmonary artery (C)</p>
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What stimulates osmoreceptors in the hypothalamus?

<p>Depleted plasma volume (B)</p>
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Which hormone is released to retain volume in response to depleted plasma volume?

<p>ADH (D)</p>
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What is the function of angiotensin II in the Renin-Angiotensin-Aldosterone System?

<p>Stimulates aldosterone secretion and vasoconstriction (A)</p>
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What is the main function of aldosterone in the body?

<p>Stimulates reabsorption of sodium and water (C)</p>
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What causes symptoms like convulsions and hypotension in hypernatremia?

<p>Water loss or sodium gain (A)</p>
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What is the normal range for calcium levels in the blood?

<p>$8.6-10.5$ (A)</p>
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What is the main function of potassium in the body?

<p>Regulates nerve impulses and muscle contraction (A)</p>
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What causes hypokalemia?

<p>Increased excretion and hyperaldosteronism (A)</p>
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What does hypocalcemia lead to in terms of neuromuscular excitability?

<p>$Decrease$ (B)</p>
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Metabolic acidosis is characterized by:

<p>$Low pH and low bicarbonate levels$ (A)</p>
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Which protective mechanism against UTIs includes acidic and high osmolality of urea?

<p>Acidic and high osmolality of urea (D)</p>
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What is a common pathogen responsible for Uncomplicated Cystitis?

<p>E.coli (D)</p>
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What is the main symptom of interstitial cystitis?

<p>Chronic pelvic pain (C)</p>
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Which condition affects one or both upper urinary tracts, including the renal pelvis and interstitium?

<p>Pyelonephritis (C)</p>
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What is the characteristic symptom of acute pyelonephritis in older adults?

<p>Low grade fever and malaise (D)</p>
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In glomerulonephritis, what leads to hematuria with RBC casts and proteinuria?

<p>Thickening of the glomerular basement membrane (D)</p>
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Which receptor is stimulated by hyperosmolality and dry mouth to cause thirst sensation?

<p>Osmolality receptors (A)</p>
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What is the major function of angiotensin II in the Renin-Angiotensin-Aldosterone System?

<p>Stimulating the secretion of aldosterone (C)</p>
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What is the manifestation of severe hypokalemia?

<p>Muscle weakness and loss of muscle tone (B)</p>
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What is the primary function of aldosterone in potassium regulation?

<p>Pulling potassium into cells (B)</p>
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What is the primary role of calcitonin in calcium homeostasis?

<p>Decreases plasma calcium levels by inhibiting absorption in gut and kidney (A)</p>
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What is the mechanism behind the manifestation of hypophosphatemia?

<p>Diminished release of oxygen due to low phosphate levels (D)</p>
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What is the primary function of surfactant in the alveoli?

<p>Keeps alveoli open and free of fluid (D)</p>
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In which condition does chloride play an important role as an extracellular ion?

<p>Following sodium and showing inverse relationship to bicarbonate (A)</p>
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Which cells in the alveoli provide the alveolar structure?

<p>Type 1 alveolar cells (A)</p>
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What is the main role of pulmonary circulation in the body?

<p>To deliver nutrients to lung tissue (B)</p>
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Which circulation system serves the bronchi and other lung structures?

<p>Systemic circulation (D)</p>
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What is the pressure difference between pulmonary and systemic circulations?

<p>$18$ mmHg vs. $90$ mmHg (D)</p>
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What is the function of alveolar macrophages in the respiratory system?

<p>Ingest foreign material (B)</p>
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What is the primary difference between cystitis and pyelonephritis?

<p>The location of inflammation in the urinary tract (A)</p>
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Which factor distinguishes interstitial cystitis from other forms of cystitis?

<p>Presence of autoimmune reaction (B)</p>
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What is a common protective mechanism against urinary tract infections according to the text?

<p>Tamm-Horsfall protein (C)</p>
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In acute pyelonephritis, what is the two-step process that leads to inflammatory response?

<p>Release of mediators and increased permeability (C)</p>
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What is the main characteristic symptom of chronic pyelonephritis?

<p>Progressive renal failure (C)</p>
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What is the primary pathophysiological process in glomerulonephritis?

<p>Deposition of immune complexes in the glomerulus (D)</p>
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What is the primary function of alveoli in the respiratory system?

<p>Facilitate gas exchange by adding O2 and removing CO2 (B)</p>
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Which cells in the alveoli prevent lung collapse by producing surfactant?

<p>Type 2 alveolar cells (D)</p>
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What is the primary role of the pulmonary circulation system?

<p>Facilitate gas exchange in the alveolar capillaries (A)</p>
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How does the pressure in the pulmonary circulation compare to the systemic circulation?

<p>Systemic circulation is higher pressure (A)</p>
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What is the function of surfactant in the alveoli?

<p>Prevent lung collapse by decreasing surface tension (D)</p>
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Which circulation system serves the bronchi and other lung structures?

<p>Systemic circulation (A)</p>
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What is the primary role of angiotensin II in the Renin-Angiotensin-Aldosterone System?

<p>Stimulates the secretion of aldosterone for sodium and water reabsorption (D)</p>
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What is the primary function of aldosterone in potassium regulation?

<p>Increases potassium uptake by cells (C)</p>
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What is the main manifestation of severe hypernatremia?

<p>Convulsions and hypotension (C)</p>
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What role do baroreceptors play in the body?

<p>Influence renal vasculature perfusion (A)</p>
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What does hyperchloremia indicate?

<p>High chloride levels in the blood (C)</p>
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Which condition can cause hypokalemia?

<p>Increased intake of potassium-rich foods (A)</p>
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What is a common manifestation of severe hypomagnesemia?

<p>'Flaccid' muscle tone and cardiac arrest (C)</p>
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'Isotonic alterations' refer to changes in total body water along with proportional electrolyte change without a change in concentration. Which of the following is an example of isotonic volume excess?

<p>Hypervolemia caused by excess diaphoresis (A)</p>
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What is a characteristic manifestation of respiratory acidosis?

<p>Restlessness and convulsions (B)</p>
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What role does renin play in the Renin-Angiotensin-Aldosterone System?

<p>Increases perfusion in renal vasculature (C)</p>
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Which protective mechanism against urinary tract infections is described as having the ability to evade the host's defense mechanism?

<p>Tamm-Horsfall protein (C)</p>
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In cystitis, the ureterovesical junction closes to prevent what?

<p>Reflux (B)</p>
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Phagocytosis of bacteria in urine is maximized at what pH range?

<p>6.5-7.5 (D)</p>
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What is a common pathogen responsible for pyelonephritis, especially in older adults?

<p>Proteus mirabilis (D)</p>
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Chronic pyelonephritis can lead to scarring in the kidneys due to recurrent episodes of what?

<p>Acute inflammation (D)</p>
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In glomerulonephritis, what is the primary cause of hematuria with RBC casts and proteinuria?

<p>Formation of immune complexes in circulation (C)</p>
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What is the most characteristic symptom of interstitial cystitis?

<p>Chronic pelvic pain (C)</p>
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What is the primary function of the alveoli in the respiratory system?

<p>Facilitating gas exchange with the blood (D)</p>
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Which cells in the alveoli provide the alveolar structure?

<p>Type 1 alveolar cells (D)</p>
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What is the main role of pulmonary circulation in the body?

<p>Facilitating gas exchange in the alveolar capillaries (D)</p>
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What distinguishes interstitial cystitis from other forms of cystitis?

<p>Inflammatory response in renal pelvis and interstitium (C)</p>
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What is the characteristic symptom of acute pyelonephritis in older adults?

<p>Malaise (B)</p>
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What is the pressure difference between pulmonary and systemic circulations?

<p>-18mmHg (A)</p>
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What is the primary cause of hematuria with RBC casts and proteinuria in glomerulonephritis?

<p>Thickening of the glomerular basement membrane (D)</p>
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Which protective mechanism against urinary tract infections involves Tamm-Horsfall protein?

<p>Mucus-secreting glands in women (A)</p>
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What is the role of Lewis blood group in susceptibility to bladder inflammation?

<p>Higher risk due to genetic factors (D)</p>
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In interstitial cystitis, what autoimmune reaction leads to an inflammatory response?

<p>Mast cell activation (D)</p>
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What is the primary function of the ureterovesical junction in preventing urinary tract infections?

<p>Closing to prevent reflux (D)</p>
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What is the main function of the Renin-Angiotensin-Aldosterone System in response to decreased plasma volume?

<p>Activates the release of aldosterone to retain fluid (D)</p>
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In hypomagnesemia, what is a common manifestation of neuromuscular irritability?

<p>Convulsions (D)</p>
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What is the primary function of angiotensin II in the Renin-Angiotensin-Aldosterone System?

<p>Stimulates the secretion of aldosterone (D)</p>
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What is a common manifestation of severe hypernatremia?

<p>Convulsions (C)</p>
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In hypocalcemia, what can manifest as a symptom due to decreased neuromuscular excitability?

<p>Heart block (A)</p>
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What is the primary role of aldosterone in the body's potassium regulation?

<p>Promotes sodium reabsorption (B)</p>
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What is a characteristic manifestation of metabolic acidosis?

<p>Muscle twitching (D)</p>
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What is a common cause of hyperphosphatemia associated with low calcium levels?

<p>Bicarbonate deficit (B)</p>
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What is the primary function of phosphate in the human body?

<p>Regulates ICF osmolality (C)</p>
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How does isotonic volume excess manifest in the body?

<p>No change in concentration but increase in total body water (D)</p>
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What is the primary role of surfactant in the alveoli?

<p>Prevents lung collapse by decreasing surface tension (D)</p>
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Which cells in the alveoli ingest foreign material and remove it through the lymphatic system?

<p>Alveolar macrophages (A)</p>
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Why does the pulmonary circulation have a lower pressure compared to the systemic circulation?

<p>To facilitate gas exchange efficiently (C)</p>
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What is the function of bronchial circulation in the lungs?

<p>Supplies blood to trachea and bronchial tree (B)</p>
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What is the primary purpose of alveolar epithelial cells in the respiratory system?

<p>Facilitate gas exchange by providing alveolar structure (D)</p>
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How does surfactant in the alveoli contribute to airflow during respiration?

<p>Decreases surface tension to prevent lung collapse (D)</p>
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What is the primary function of angiotensin II in the Renin-Angiotensin-Aldosterone System?

<p>Causes release of aldosterone (A)</p>
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What is the main role of pulmonary circulation in the body?

<p>Assisting in oxygenation of blood (D)</p>
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Which electrolyte imbalance is associated with manifestations such as neuromuscular irritability, tetany, and convulsions?

<p>Hypomagnesemia (A)</p>
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What does hypernatremia lead to as a manifestation?

<p>Convulsions and hypotension (C)</p>
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What is the primary function of potassium in the body?

<p>Promotes muscle contraction (C)</p>
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What is the primary function of aldosterone in the body?

<p>Promotes water reabsorption in the kidneys (A)</p>
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Which substance converts angiotensin I to its active form, angiotensin II?

<p>ACE in pulmonary vessels (B)</p>
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What is the major intracellular cation responsible for the transmission of nerve impulses and muscle contractions?

<p>Potassium (C)</p>
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What is the primary function of renin in the Renin-Angiotensin-Aldosterone System?

<p>Stimulates aldosterone release (B)</p>
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In hypernatremia, what manifestations are commonly associated with this condition?

<p>Convulsions, pulmonary edema, hypotension (B)</p>
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Which of the following is a protective mechanism against urinary tract infections described in the text?

<p>Bactericidal secretions (B)</p>
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What is the most common pathogen responsible for uncomplicated cystitis?

<p>E. coli (B)</p>
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Which symptom is characteristic of interstitial cystitis?

<p>Bladder fullness (D)</p>
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What is the primary cause of hematuria with RBC casts in glomerulonephritis?

<p>Proteinuria (C)</p>
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Which condition results from persistent or recurring episodes of acute pyelonephritis?

<p>Renal failure (C)</p>
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What is the two-step process that leads to inflammatory response in acute pyelonephritis?

<p>Mediators increase permeability and cause WBC infiltration (D)</p>
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Which symptom is common in older adults with pyelonephritis?

<p>Low grade fever and malaise (A)</p>
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What is the function of immune complexes formed in glomerulonephritis?

<p>Activate complement system (A)</p>
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